Inpp4b (inositol polyphosphate-4-phosphatase type II B) - Rat Genome Database

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Gene: Inpp4b (inositol polyphosphate-4-phosphatase type II B) Chinchilla lanigera
Analyze
Symbol: Inpp4b
Name: inositol polyphosphate-4-phosphatase type II B
RGD ID: 8719200
Description: ENCODES a protein that exhibits lipid binding (ortholog); phosphatidylinositol bisphosphate phosphatase activity (ortholog); phosphatidylinositol trisphosphate phosphatase activity (ortholog); INVOLVED IN cellular calcium ion homeostasis (ortholog); inositol phosphate dephosphorylation (ortholog); negative regulation of osteoclast differentiation (ortholog); PARTICIPATES IN inositol phosphate metabolic pathway; phosphoinositide metabolic pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); hepatocellular carcinoma (ortholog); pancreatic carcinoma (ortholog); FOUND IN cytoplasm (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inositol polyphosphate-4-phosphatase, type II, 105kDa; type II inositol 3,4-bisphosphate 4-phosphatase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955471938,005 - 1,291,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955471938,005 - 1,291,695 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Inpp4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955471938,005 - 1,291,695 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955471938,005 - 1,291,695 (+)NCBIChiLan1.0ChiLan1.0
INPP4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384142,023,160 - 142,846,535 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4142,023,160 - 142,847,432 (-)EnsemblGRCh38hg38GRCh38
GRCh374142,944,313 - 143,767,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364143,168,631 - 143,987,054 (-)NCBINCBI36hg18NCBI36
Build 344143,307,498 - 143,710,137NCBI
Celera4140,279,978 - 141,098,274 (-)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4138,678,404 - 139,496,966 (-)NCBIHuRef
CHM1_14142,926,560 - 143,744,866 (-)NCBICHM1_1
T2T-CHM13v2.04145,340,544 - 146,163,746 (-)NCBI
Inpp4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39882,068,895 - 82,865,553 (+)NCBIGRCm39mm39
GRCm39 Ensembl882,069,185 - 82,854,543 (+)Ensembl
GRCm38881,342,266 - 82,134,312 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl881,342,556 - 82,127,914 (+)EnsemblGRCm38mm10GRCm38
MGSCv37884,239,099 - 84,646,460 (+)NCBIGRCm37mm9NCBIm37
MGSCv36884,610,947 - 85,018,308 (+)NCBImm8
Celera886,003,317 - 86,422,617 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map839.02NCBI
Inpp4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21925,920,189 - 26,670,085 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1925,925,358 - 26,280,634 (-)Ensembl
Rnor_6.01929,592,889 - 30,341,528 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1929,597,905 - 29,968,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01940,508,684 - 41,132,035 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41927,722,430 - 28,363,639 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11927,727,256 - 28,484,803 (-)NCBI
Celera1925,451,220 - 26,189,580 (-)NCBICelera
Cytogenetic Map19q11NCBI
INPP4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14145,707,005 - 146,513,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4145,706,307 - 146,141,029 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04134,405,934 - 135,213,851 (-)NCBIMhudiblu_PPA_v0panPan3
INPP4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.119826,711 - 1,192,340 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl19850,784 - 1,186,498 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha191,074,484 - 1,439,447 (+)NCBI
ROS_Cfam_1.019847,593 - 1,213,382 (+)NCBI
ROS_Cfam_1.0 Ensembl19872,222 - 1,211,381 (+)Ensembl
UMICH_Zoey_3.119829,445 - 1,194,997 (+)NCBI
UNSW_CanFamBas_1.0191,190,522 - 1,556,374 (+)NCBI
UU_Cfam_GSD_1.0191,544,331 - 1,910,402 (+)NCBI
Inpp4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530147,989,723 - 48,731,310 (+)NCBI
SpeTri2.0NW_0049365355,427,131 - 6,168,622 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INPP4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl885,084,133 - 85,514,516 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1884,812,041 - 85,555,200 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2890,440,950 - 90,810,384 (+)NCBISscrofa10.2Sscrofa10.2susScr3
INPP4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1788,929,249 - 89,732,375 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl788,979,493 - 89,461,475 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603768,478,295 - 69,289,053 (-)NCBIVero_WHO_p1.0
Inpp4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248531,355,384 - 1,868,812 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248531,350,577 - 2,147,616 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000010573   ⟹   ENSCLAP00000010442
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955471938,005 - 1,291,695 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000010574   ⟹   ENSCLAP00000010443
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955471938,005 - 1,291,466 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000010575   ⟹   ENSCLAP00000010444
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955471944,483 - 1,290,257 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000010576   ⟹   ENSCLAP00000010445
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554711,056,494 - 1,291,466 (+)Ensembl
RefSeq Acc Id: XM_005400855   ⟹   XP_005400912
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955471938,005 - 1,291,466 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400857   ⟹   XP_005400914
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955471938,005 - 1,291,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005400858   ⟹   XP_005400915
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554711,056,809 - 1,291,466 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400912 (Get FASTA)   NCBI Sequence Viewer  
  XP_005400914 (Get FASTA)   NCBI Sequence Viewer  
  XP_005400915 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005400914   ⟸   XM_005400857
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005400912   ⟸   XM_005400855
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005400915   ⟸   XM_005400858
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000010444   ⟸   ENSCLAT00000010575
RefSeq Acc Id: ENSCLAP00000010445   ⟸   ENSCLAT00000010576
RefSeq Acc Id: ENSCLAP00000010442   ⟸   ENSCLAT00000010573
RefSeq Acc Id: ENSCLAP00000010443   ⟸   ENSCLAT00000010574
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007216 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000010442 ENTREZGENE
  ENSCLAP00000010442.1 UniProtKB/TrEMBL
  ENSCLAP00000010443 ENTREZGENE
  ENSCLAP00000010443.1 UniProtKB/TrEMBL
  ENSCLAP00000010444.1 UniProtKB/TrEMBL
  ENSCLAP00000010445 ENTREZGENE
  ENSCLAP00000010445.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010573 ENTREZGENE
  ENSCLAT00000010573.1 UniProtKB/TrEMBL
  ENSCLAT00000010574 ENTREZGENE
  ENSCLAT00000010574.1 UniProtKB/TrEMBL
  ENSCLAT00000010575.1 UniProtKB/TrEMBL
  ENSCLAT00000010576 ENTREZGENE
  ENSCLAT00000010576.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  INPP4 UniProtKB/TrEMBL
NCBI Gene Inpp4b ENTREZGENE
PANTHER PTHR12187 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2V5T1_CHILA UniProtKB/TrEMBL
  A0A8C2V6F9_CHILA UniProtKB/TrEMBL
  A0A8C2V8P1_CHILA UniProtKB/TrEMBL
  A0A8C2VBT3_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Inpp4b  inositol polyphosphate-4-phosphatase type II B    inositol polyphosphate-4-phosphatase, type II, 105kDa  Symbol and/or name change 5135510 APPROVED