Tap2 (transporter 2, ATP binding cassette subfamily B member) - Rat Genome Database

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Gene: Tap2 (transporter 2, ATP binding cassette subfamily B member) Chinchilla lanigera
Analyze
Symbol: Tap2
Name: transporter 2, ATP binding cassette subfamily B member
RGD ID: 8718847
Description: ENCODES a protein that exhibits ABC-type peptide antigen transporter activity (ortholog); ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN antigen processing and presentation of endogenous peptide antigen via MHC class I (ortholog); antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (ortholog); antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Alzheimer's disease (ortholog); ankylosing spondylitis (ortholog); FOUND IN endoplasmic reticulum (ortholog); integral component of endoplasmic reticulum membrane (ortholog); integral component of membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: antigen peptide transporter 2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,477,341 - 1,498,575 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,480,217 - 1,499,032 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Tap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,477,341 - 1,498,575 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,480,217 - 1,499,032 (-)NCBIChiLan1.0ChiLan1.0
TAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,821,831 - 32,838,739 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl632,821,833 - 32,838,739 (-)EnsemblGRCh38hg38GRCh38
GRCh37632,789,608 - 32,806,516 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,897,588 - 32,914,525 (-)NCBINCBI36hg18NCBI36
Build 34632,897,587 - 32,914,482NCBI
Celera634,338,665 - 34,355,440 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef632,531,964 - 32,548,753 (-)NCBIHuRef
CHM1_1632,790,604 - 32,807,372 (-)NCBICHM1_1
T2T-CHM13v2.0632,643,187 - 32,660,143 (-)NCBI
Tap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,423,453 - 34,435,295 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,422,501 - 34,435,295 (+)Ensembl
GRCm381734,204,479 - 34,216,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,203,527 - 34,216,321 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,341,424 - 34,353,266 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,814,778 - 33,826,596 (+)NCBImm8
Celera1736,957,240 - 36,969,164 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Tap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,636,347 - 4,650,387 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl204,636,357 - 4,650,407 (-)Ensembl
Rnor_6.0203,995,544 - 4,009,587 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,995,544 - 4,009,587 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,198,258 - 5,212,624 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,259,226 - 7,273,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0206,075,031 - 6,089,429 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,770,446 - 4,784,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,770,672 - 4,784,715 (-)NCBI
Celera206,237,501 - 6,251,447 (-)NCBICelera
Cytogenetic Map20p12NCBI
TAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1633,513,321 - 33,523,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,507,332 - 33,523,750 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0632,394,586 - 32,408,297 (-)NCBIMhudiblu_PPA_v0panPan3
TAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,407,512 - 2,417,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,378,126 - 2,432,303 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,489,442 - 2,499,082 (-)NCBI
ROS_Cfam_1.0122,689,106 - 2,699,061 (-)NCBI
ROS_Cfam_1.0 Ensembl122,652,372 - 2,699,034 (-)Ensembl
UMICH_Zoey_3.1122,406,835 - 2,416,483 (-)NCBI
UNSW_CanFamBas_1.0122,488,331 - 2,497,947 (-)NCBI
UU_Cfam_GSD_1.0122,562,598 - 2,572,236 (-)NCBI
Tap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,036,847 - 38,046,599 (-)NCBI
SpeTri2.0NW_00493647625,913,699 - 25,923,419 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,045,685 - 25,056,300 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,045,085 - 25,056,915 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,412,165 - 29,423,473 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,266,870 - 39,277,658 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,614,899 - 32,625,447 (-)NCBIVero_WHO_p1.0
Tap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,827,706 - 23,837,356 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475423,827,782 - 23,845,690 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018629   ⟹   ENSCLAP00000018448
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554371,477,341 - 1,498,575 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000018630   ⟹   ENSCLAP00000018449
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554371,477,341 - 1,498,563 (-)Ensembl
RefSeq Acc Id: XM_013516933   ⟹   XP_013372387
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554371,480,217 - 1,499,032 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013516934   ⟹   XP_013372388
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554371,480,217 - 1,499,030 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013372387 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372388 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013372387   ⟸   XM_013516933
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013372388   ⟸   XM_013516934
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000018448   ⟸   ENSCLAT00000018629
RefSeq Acc Id: ENSCLAP00000018449   ⟸   ENSCLAT00000018630

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012654 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000018448 ENTREZGENE
  ENSCLAP00000018448.1 UniProtKB/TrEMBL
  ENSCLAP00000018449.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018629 ENTREZGENE
  ENSCLAT00000018629.1 UniProtKB/TrEMBL
  ENSCLAT00000018630.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_Tap-like UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABC_transporter-like_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Tap2/ABCB3 UniProtKB/TrEMBL
  Type_1_exporter UniProtKB/TrEMBL
NCBI Gene Tap2 ENTREZGENE
PANTHER PTHR24221 UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PRINTS TAP2PROTEIN UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
TIGRFAMs 3a01208 UniProtKB/TrEMBL
UniProt A0A8C2VP24_CHILA UniProtKB/TrEMBL
  A0A8C2YRR4_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Tap2  transporter 2, ATP binding cassette subfamily B member    transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)  Symbol and/or name change 5135510 APPROVED