Npc1 (NPC intracellular cholesterol transporter 1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Npc1 (NPC intracellular cholesterol transporter 1) Chinchilla lanigera
Analyze
Symbol: Npc1
Name: NPC intracellular cholesterol transporter 1
RGD ID: 8716046
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN adult walking behavior (ortholog); autophagy (ortholog); cellular response to low-density lipoprotein particle stimulus (ortholog); ASSOCIATED WITH Ataxia (ortholog); atherosclerosis (ortholog); brucellosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: Niemann-Pick disease, type C1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540211,699,434 - 11,742,899 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540211,699,434 - 11,742,899 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References


Genomics

Comparative Map Data
Npc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540211,699,434 - 11,742,899 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540211,699,434 - 11,742,899 (-)NCBIChiLan1.0ChiLan1.0
NPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1823,506,184 - 23,586,506 (-)EnsemblGRCh38hg38GRCh38
GRCh381823,506,184 - 23,586,506 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371821,111,406 - 21,166,470 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371821,086,148 - 21,166,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361819,365,461 - 19,420,468 (-)NCBINCBI36hg18NCBI36
Build 341819,365,461 - 19,420,426NCBI
Celera1817,927,454 - 17,982,730 (-)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1817,966,414 - 18,021,712 (-)NCBIHuRef
CHM1_11821,038,743 - 21,093,877 (-)NCBICHM1_1
Npc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391812,322,751 - 12,369,851 (-)NCBIGRCm39mm39
GRCm381812,189,694 - 12,236,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1812,189,692 - 12,236,400 (-)EnsemblGRCm38mm10GRCm38
MGSCv371812,348,203 - 12,394,895 (-)NCBIGRCm37mm9NCBIm37
MGSCv361812,333,398 - 12,379,894 (-)NCBImm8
Celera1812,423,091 - 12,469,783 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map186.15NCBI
Npc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2183,379,482 - 3,425,100 (-)NCBI
Rnor_6.0 Ensembl183,616,878 - 3,662,683 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0183,616,878 - 3,662,656 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,626,015 - 3,671,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,725,415 - 3,777,707 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,725,710 - 3,726,684 (-)NCBI
Celera183,239,322 - 3,285,547 (-)NCBICelera
Cytogenetic Map18p13NCBI
NPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11820,409,040 - 20,463,623 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1820,409,040 - 20,463,623 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01816,783,096 - 16,838,301 (-)NCBIMhudiblu_PPA_v0panPan3
NPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl764,760,121 - 64,802,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1764,764,941 - 64,802,507 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Npc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365502,983,172 - 3,032,222 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6108,402,877 - 108,450,990 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16108,403,126 - 108,450,486 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26101,001,696 - 101,049,542 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11856,956,557 - 57,007,951 (+)NCBI
ChlSab1.1 Ensembl1856,956,174 - 57,007,474 (+)Ensembl
Npc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247708,592,473 - 8,642,063 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000012500   ⟹   ENSCLAP00000012357
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540211,699,434 - 11,742,899 (-)Ensembl
RefSeq Acc Id: XM_005372706   ⟹   XP_005372763
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540211,699,434 - 11,742,899 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005372763 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005372763   ⟸   XM_005372706
- Sequence:
RefSeq Acc Id: ENSCLAP00000012357   ⟸   ENSCLAT00000012500


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008539 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000012357 ENTREZGENE
Ensembl Transcript ENSCLAT00000012500 ENTREZGENE
NCBI Gene Npc1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Npc1  NPC intracellular cholesterol transporter 1    Niemann-Pick disease, type C1  Symbol and/or name change 5135510 APPROVED