Sez6l (seizure related 6 homolog like) - Rat Genome Database

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Gene: Sez6l (seizure related 6 homolog like) Chinchilla lanigera
Analyze
Symbol: Sez6l
Name: seizure related 6 homolog like
RGD ID: 8710588
Description: INVOLVED IN adult locomotory behavior (ortholog); cerebellar Purkinje cell layer development (ortholog); regulation of protein kinase C signaling (ortholog); ASSOCIATED WITH cataract 23 (ortholog); genetic disease (ortholog); prostate cancer (ortholog); FOUND IN endoplasmic reticulum (ortholog); glutamatergic synapse (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: seizure related 6 homolog (mouse)-like
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955455927,521 - 989,502 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955455816,129 - 992,776 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Sez6l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955455927,521 - 989,502 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955455816,129 - 992,776 (+)NCBIChiLan1.0ChiLan1.0
SEZ6L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382226,169,462 - 26,383,596 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2226,169,462 - 26,383,597 (+)EnsemblGRCh38hg38GRCh38
GRCh372226,565,428 - 26,779,562 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362224,895,480 - 25,106,437 (+)NCBINCBI36Build 36hg18NCBI36
Build 342224,890,033 - 25,100,988NCBI
Celera2210,369,614 - 10,583,724 (+)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef229,512,935 - 9,727,121 (+)NCBIHuRef
CHM1_12226,524,986 - 26,739,070 (+)NCBICHM1_1
T2T-CHM13v2.02226,631,737 - 26,845,974 (+)NCBIT2T-CHM13v2.0
Sez6l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395112,567,020 - 112,726,401 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5112,567,017 - 112,725,051 (-)EnsemblGRCm39 Ensembl
GRCm385112,419,151 - 112,578,535 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5112,419,151 - 112,577,185 (-)EnsemblGRCm38mm10GRCm38
MGSCv375112,848,176 - 113,006,205 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365112,659,454 - 112,817,501 (-)NCBIMGSCv36mm8
Celera5109,539,606 - 109,699,399 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map554.72NCBI
Sez6l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,725,330 - 49,882,222 (+)NCBIGRCr8
mRatBN7.21244,064,901 - 44,221,814 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1244,064,935 - 44,219,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,233,413 - 45,388,634 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01245,844,198 - 45,998,919 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01244,904,725 - 45,059,456 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01250,090,345 - 50,243,020 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1250,090,464 - 50,241,995 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01251,848,678 - 52,001,047 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41214,402,252 - 14,554,786 (-)ENTREZGENERGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.41914,402,252 - 14,554,786 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1245,664,779 - 45,802,672 (+)ENTREZGENECelera
Cytogenetic Map12q16NCBI
SEZ6L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22336,174,549 - 36,389,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12238,873,249 - 39,088,066 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0227,230,597 - 7,445,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12224,955,631 - 25,169,558 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2225,077,259 - 25,163,881 (+)Ensemblpanpan1.1panPan2
SEZ6L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12619,889,913 - 20,079,305 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2619,888,319 - 20,076,021 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2619,754,682 - 19,943,624 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02620,255,605 - 20,443,125 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2620,255,614 - 20,438,447 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12619,960,208 - 20,159,834 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02620,226,265 - 20,415,615 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02620,295,389 - 20,485,072 (+)NCBIUU_Cfam_GSD_1.0
Sez6l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118114,856,491 - 114,914,367 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936657963,402 - 1,014,099 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936657956,340 - 1,014,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEZ6L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1443,802,706 - 44,001,624 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11443,802,482 - 44,001,643 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21446,680,110 - 46,881,868 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEZ6L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1199,069,476 - 9,284,540 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl199,069,746 - 9,284,543 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045116,827,992 - 117,071,914 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sez6l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247472,879,589 - 2,941,759 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247472,754,556 - 2,944,644 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014160   ⟹   ENSCLAP00000014003
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955455927,521 - 989,502 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014161   ⟹   ENSCLAP00000014004
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955455927,521 - 989,502 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014162   ⟹   ENSCLAP00000014005
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955455927,521 - 989,502 (+)Ensembl
RefSeq Acc Id: XM_005396140   ⟹   XP_005396197
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955455816,129 - 992,776 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013520286   ⟹   XP_013375740
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955455879,756 - 992,776 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396197 (Get FASTA)   NCBI Sequence Viewer  
  XP_013375740 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000014003
  ENSCLAP00000014003.1
  ENSCLAP00000014004.1
  ENSCLAP00000014005
  ENSCLAP00000014005.1
Reference Protein Sequences
RefSeq Acc Id: XP_005396197   ⟸   XM_005396140
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VDL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375740   ⟸   XM_013520286
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VDL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000014005   ⟸   ENSCLAT00000014162
RefSeq Acc Id: ENSCLAP00000014003   ⟸   ENSCLAT00000014160
RefSeq Acc Id: ENSCLAP00000014004   ⟸   ENSCLAT00000014161
Protein Domains
CUB   Sushi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009675 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014160 ENTREZGENE
  ENSCLAT00000014160.1 UniProtKB/TrEMBL
  ENSCLAT00000014161.1 UniProtKB/TrEMBL
  ENSCLAT00000014162 ENTREZGENE
  ENSCLAT00000014162.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/TrEMBL
InterPro CUB_dom UniProtKB/TrEMBL
  Sperma_CUB_dom_sf UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/TrEMBL
NCBI Gene Sez6l ENTREZGENE
PANTHER PROTEIN CBR-CLEC-78 UniProtKB/TrEMBL
  SEIZURE 6-LIKE PROTEIN UniProtKB/TrEMBL
Pfam CUB UniProtKB/TrEMBL
  Sushi UniProtKB/TrEMBL
PROSITE CUB UniProtKB/TrEMBL
  SUSHI UniProtKB/TrEMBL
SMART CCP UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
Superfamily-SCOP SSF49854 UniProtKB/TrEMBL
  SSF57535 UniProtKB/TrEMBL
UniProt A0A8C2VDJ1_CHILA UniProtKB/TrEMBL
  A0A8C2VDL2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YPM0_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Sez6l  seizure related 6 homolog like    seizure related 6 homolog (mouse)-like  Symbol and/or name change 5135510 APPROVED