Kat2b (lysine acetyltransferase 2B) - Rat Genome Database

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Gene: Kat2b (lysine acetyltransferase 2B) Chinchilla lanigera
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Symbol: Kat2b
Name: lysine acetyltransferase 2B
RGD ID: 8707694
Description: ENCODES a protein that exhibits acetyltransferase activity (ortholog); chromatin binding (ortholog); cyclin-dependent protein serine/threonine kinase inhibitor activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); cellular response to oxidative stress (ortholog); cellular response to parathyroid hormone stimulus (ortholog); PARTICIPATES IN cortisol signaling pathway; histone modification pathway; p53 signaling pathway; ASSOCIATED WITH 3p deletion syndrome (ortholog); breast cancer (ortholog); Coronary Disease (ortholog); FOUND IN A band (ortholog); actomyosin (ortholog); ATAC complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone acetyltransferase KAT2B; K(lysine) acetyltransferase 2B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543012,128,069 - 12,198,117 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543012,109,493 - 12,196,102 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543012,128,069 - 12,198,117 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543012,109,493 - 12,196,102 (+)NCBIChiLan1.0ChiLan1.0
KAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38320,040,446 - 20,154,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl320,040,446 - 20,154,404 (+)EnsemblGRCh38hg38GRCh38
GRCh37320,081,938 - 20,195,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36320,056,528 - 20,170,900 (+)NCBINCBI36Build 36hg18NCBI36
Build 34320,056,527 - 20,170,898NCBI
Celera320,022,291 - 20,136,515 (+)NCBICelera
Cytogenetic Map3p24.3NCBI
HuRef320,021,882 - 20,135,958 (+)NCBIHuRef
CHM1_1320,033,609 - 20,147,728 (+)NCBICHM1_1
T2T-CHM13v2.0320,044,513 - 20,158,472 (+)NCBIT2T-CHM13v2.0
Kat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391753,873,802 - 53,979,749 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1753,873,889 - 53,979,748 (+)EnsemblGRCm39 Ensembl
GRCm381753,566,774 - 53,672,721 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1753,566,861 - 53,672,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv371753,706,640 - 53,812,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361753,032,244 - 53,137,649 (+)NCBIMGSCv36mm8
Celera1757,012,579 - 57,114,621 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1727.86NCBI
Kat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr896,799,101 - 6,903,616 (+)NCBIGRCr8
mRatBN7.296,562,525 - 6,667,064 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl96,562,288 - 6,667,064 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.094,440,982 - 4,492,949 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl94,440,982 - 4,447,715 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.093,479,552 - 3,531,771 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49882,928 - 889,661NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19882,927 - 889,661NCBI
Cytogenetic Map9q11NCBI
KAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2220,004,090 - 20,118,205 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1320,008,861 - 20,122,967 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0319,956,067 - 20,070,637 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1320,286,080 - 20,399,970 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl320,286,865 - 20,400,770 (+)Ensemblpanpan1.1panPan2
KAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12323,166,722 - 23,242,447 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2323,168,600 - 23,233,478 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2323,190,019 - 23,289,543 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02323,651,391 - 23,751,080 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2323,651,410 - 23,751,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12323,363,816 - 23,463,316 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02323,429,027 - 23,528,696 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02323,675,265 - 23,774,811 (-)NCBIUU_Cfam_GSD_1.0
Kat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118179,183,147 - 179,277,064 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647312,344,343 - 12,417,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647312,341,545 - 12,415,637 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl136,985,235 - 7,100,345 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1136,985,151 - 7,099,771 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2137,975,063 - 8,051,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KAT2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11564,769,590 - 64,885,536 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1564,770,185 - 64,886,219 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604137,788,721 - 37,904,736 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kat2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248215,387,212 - 5,489,013 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000009497   ⟹   ENSCLAP00000009368
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543012,128,069 - 12,198,117 (+)Ensembl
RefSeq Acc Id: XM_005387463   ⟹   XP_005387520
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543012,109,493 - 12,196,102 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005387464   ⟹   XP_005387521
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543012,109,709 - 12,196,102 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515665   ⟹   XP_013371119
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543012,109,709 - 12,196,102 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515666   ⟹   XP_013371120
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543012,109,665 - 12,196,102 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005387520 (Get FASTA)   NCBI Sequence Viewer  
  XP_005387521 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371119 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371120 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009368
  ENSCLAP00000009368.1
RefSeq Acc Id: XP_005387520   ⟸   XM_005387463
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387521   ⟸   XM_005387464
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V7P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371120   ⟸   XM_013515666
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V7P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013371119   ⟸   XM_013515665
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V7P3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000009368   ⟸   ENSCLAT00000009497
Protein Domains
Bromo   N-acetyltransferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006506 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009497 ENTREZGENE
  ENSCLAT00000009497.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.10 UniProtKB/TrEMBL
  3.40.630.30 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  GCN5 UniProtKB/TrEMBL
  GNAT_dom UniProtKB/TrEMBL
  PCAF_N UniProtKB/TrEMBL
NCBI Gene Kat2b ENTREZGENE
PANTHER HISTONE ACETYLTRANSFERASE KAT2B UniProtKB/TrEMBL
  PTHR45750 UniProtKB/TrEMBL
Pfam Acetyltransf_1 UniProtKB/TrEMBL
  Bromodomain UniProtKB/TrEMBL
  PCAF_N UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
  GNAT UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
Superfamily-SCOP SSF47370 UniProtKB/TrEMBL
  SSF55729 UniProtKB/TrEMBL
UniProt A0A8C2V7P3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Kat2b  lysine acetyltransferase 2B    K(lysine) acetyltransferase 2B  Symbol and/or name change 5135510 APPROVED