Dhrsx (dehydrogenase/reductase X-linked)

Gene: Dhrsx (dehydrogenase/reductase X-linked) Chinchilla lanigera

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Symbol:

Dhrsx

Name:

dehydrogenase/reductase X-linked

RGD ID:

8701050

Description:

INVOLVED IN positive regulation of autophagy (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN extracellular region (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dehydrogenase/reductase (SDR family) X-linked; dehydrogenase/reductase SDR family member on chromosome X

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955499	1,360,636 - 1,471,141 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of autophagy (ISO)

Cellular Component

extracellular region (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Dhrsx
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955499	1,360,636 - 1,471,141 (-)	NCBI	ChiLan1.0	ChiLan1.0

DHRSX
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	Y	2,219,506 - 2,500,976 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38	X	2,219,506 - 2,500,976 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	Y	2,219,506 - 2,502,805 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	X	2,219,506 - 2,502,805 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	Y	2,087,547 - 2,369,017 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	X	2,137,547 - 2,419,017 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	Y	2,147,547 - 2,428,975 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 36	X	2,147,547 - 2,428,975 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	6,417,033 - 6,699,196 (-)	NCBI		Celera
Cytogenetic Map	X	p22.33 and Yp11.2	NCBI
HuRef	X	82,593 - 285,774 (-)	NCBI		HuRef
CHM1_1	X	2,167,970 - 2,448,744 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	1,829,953 - 2,113,734 (-)	NCBI		T2T-CHM13v2.0
T2T-CHM13v2.0	Y	1,894,160 - 2,177,723 (-)	NCBI		T2T-CHM13v2.0

Dhrsx
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	156,390,105 - 156,410,432 (+)	NCBI	GRCm39	GRCm39	mm39
Celera	4	159,398,364 - 159,422,004 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI

Dhrsx
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	21,413,563 - 21,418,319 (+)	NCBI		GRCr8
mRatBN7.2	12	16,299,768 - 16,304,553 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	16,299,808 - 16,304,552 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	17,116,744 - 17,121,495 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	17,740,468 - 17,745,219 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	16,803,395 - 16,808,132 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	18,516,858 - 18,521,235 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	18,516,946 - 18,521,892 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	20,501,826 - 20,506,189 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	16,807,161 - 16,810,619 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	16,837,082 - 16,841,642 (+)	NCBI
Celera	12	18,049,537 - 18,053,151 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

DHRSX
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	1,940,532 - 2,242,636 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1-v2	Y	44,682,649 - 44,979,400 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	1,942,674 - 2,246,287 (-)	NCBI		NHGRI_mPanPan1
NHGRI_mPanPan1	Y	1,945,870 - 2,244,298 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	X	2,163,986 - 2,454,096 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	2,165,525 - 2,370,392 (-)	Ensembl	panpan1.1		panPan2

DHRSX
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	1,172,404 - 1,288,088 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	1,170,522 - 1,285,390 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	1,116,182 - 1,253,883 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	1,087,553 - 1,225,513 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	1,087,763 - 1,201,136 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	1,078,602 - 1,216,259 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	1,095,006 - 1,233,151 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	1,131,217 - 1,269,264 (-)	NCBI		UU_Cfam_GSD_1.0

Dhrsx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404953	723,984 - 751,417 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936644	3,625,705 - 3,652,759 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DHRSX
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	Y	5,248,447 - 5,374,873 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOC103231531
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	315,705 - 618,961 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666056	2,279,966 - 2,557,840 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dhrsx
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624834	927,152 - 1,053,855 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624834	929,478 - 1,053,851 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005406518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013505592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01063348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063349	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCB01024741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01253653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005406518 ⟹ XP_005406575

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955499	1,360,636 - 1,471,141 (-)	NCBI

Sequence:

show sequence

CGTGGCGCGGCGGCGGTGGGCGGGGCGCGGCGGCGCCATGGCGCGGGTGAGCGCGGCGCTGCGG
GTCTACGCGGTGGGGGCCGCGCTCCTGCTGCTGCAGCTGCTGCGCCGGTGCCGCGGGGGCTTCT
CGCCGCCAGTTTTCTGCCGGCAGCCGGATCGCGTGGCTGTGGTGACCGGCGGGACGGACGGCAT
CGGCTACTCCACGGCCAAGCAGCTGGCCAGGCTCGGCGTGCACGTGATCATAGCCGGAAATAAT
GAGGAGAGAGCCCAGCAAGCCGTTAGCAGAATAAAGGAAGAAACACTGAACACCAAAGGCATGT
TCCTGGGAAAGACGACAGCATGTCAGAGATTCCCCTCCAGATGGTACCCGGCTCCAGAACAGCA
CTTCCACACCCTTGGTGTGGAGTTTTTATACTGCAACCTGGCTTCCATGAAGTCCATCCGGCAG
TTCGTGAAGAATTTCAAGATGAAGAGACTCCCGCTCCATGTGCTCGTCAATAATGCTGGAGTGA
TGATGGTACCTCAGCGAAAGACCGAGGATGGATTTGAAGAACACTTTGGTCTCAACTACTTGGG
GCACTTCCTGCTCACCAGCCTCCTCCTGGACAGCCTGAAGGAGTCCGGATCCCCAGGTCGCAGC
TCCAGAGTGGTCACCGTCTCCTCTGCCACGCATTACGTGGGCGAGCTCAACCTGGAAGACCTGC
AGAGCAGCTCCTGCTACTCACCGCATGGAGCCTACGCCCGGAGCAAGCTGGCCCTGGTCATGTT
CTCCTACCACCTCCAGAGGCTGCTGGAAGCCCAGGGCTGCCACGTGACCGCTAACGTGGTGGAC
CCCGGGGTGGTCAACACGGACCTGTACAAGCACGTATTCTGGGGCACGCGTCTGGTCCAGCGGA
TCCTAGGCTGGTTGCTCTTCAAGACCCCCGATGAAGGCGCCTGGACATCTGTGTATGCGGCGGT
CAGCCCAGAGCTGGAAGGACTTGGTGGCCGCTACCTGTACAACGAGAAAGAGACCAAGTCCCTC
GAGGTCACCTATGACCAGAAGCTTCAGCAGCAGCTGTGGGCCAGAAGCTGTCAGATGACGGGAG
TCACGGACGTGACGCGTGGCACCATCTTGGACTAACTGTGTCACCTGGAGTTTGCCAACGTGGA
CTGGACTGGGACTCTGAGAAGCAGGATGCCTGAAATTCTGACATCCCCCTCCCCCCAGGGCTCG
GTCCTCAAGTCTTGAGTTGAGTGCCTTAATCTTTGCAGGAGTTCACCACCCCAAGAAATGTTGG
CAGGTGGCTCCCCAATGCCAAATTGTCACACAAGTGCCAAGGAAATTAAACCTGTCCAACTCGG

hide sequence

RefSeq Acc Id:

XM_013505592 ⟹ XP_013361046

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955499	1,360,636 - 1,471,141 (-)	NCBI

Sequence:

show sequence

CGTGGCGCGGCGGCGGTGGGCGGGGCGCGGCGGCGCCATGGCGCGGGTGAGCGCGGCGCTGCGG
GTCTACGCGGTGGGGGCCGCGCTCCTGCTGCTGCAGCTGCTGCGCCGGTGCCGCGGGGGCTTCT
CGCCGCCAGTTTTCTGCCGGCAGCCGGATCGCGTGGCTGTGGTGACCGGCGGGACGGACGGCAT
CGGCTACTCCACGGCCAAGCAGCTGGCCAGGCTCGGCGTGCACGTGATCATAGCCGGAAATAAT
GAGGAGAGAGCCCAGCAAGCCGTTAGCAGAATAAAGGAAGAAACACTGAACACCAAAGTGGAGT
TTTTATACTGCAACCTGGCTTCCATGAAGTCCATCCGGCAGTTCGTGAAGAATTTCAAGATGAA
GAGACTCCCGCTCCATGTGCTCGTCAATAATGCTGGAGTGATGATGGTACCTCAGCGAAAGACC
GAGGATGGATTTGAAGAACACTTTGGTCTCAACTACTTGGGGCACTTCCTGCTCACCAGCCTCC
TCCTGGACAGCCTGAAGGAGTCCGGATCCCCAGGTCGCAGCTCCAGAGTGGTCACCGTCTCCTC
TGCCACGCATTACGTGGGCGAGCTCAACCTGGAAGACCTGCAGAGCAGCTCCTGCTACTCACCG
CATGGAGCCTACGCCCGGAGCAAGCTGGCCCTGGTCATGTTCTCCTACCACCTCCAGAGGCTGC
TGGAAGCCCAGGGCTGCCACGTGACCGCTAACGTGGTGGACCCCGGGGTGGTCAACACGGACCT
GTACAAGCACGTATTCTGGGGCACGCGTCTGGTCCAGCGGATCCTAGGCTGGTTGCTCTTCAAG
ACCCCCGATGAAGGCGCCTGGACATCTGTGTATGCGGCGGTCAGCCCAGAGCTGGAAGGACTTG
GTGGCCGCTACCTGTACAACGAGAAAGAGACCAAGTCCCTCGAGGTCACCTATGACCAGAAGCT
TCAGCAGCAGCTGTGGGCCAGAAGCTGTCAGATGACGGGAGTCACGGACGTGACGCGTGGCACC
ATCTTGGACTAACTGTGTCACCTGGAGTTTGCCAACGTGGACTGGACTGGGACTCTGAGAAGCA
GGATGCCTGAAATTCTGACATCCCCCTCCCCCCAGGGCTCGGTCCTCAAGTCTTGAGTTGAGTG
CCTTAATCTTTGCAGGAGTTCACCACCCCAAGAAATGTTGGCAGGTGGCTCCCCAATGCCAAAT
TGTCACACAAGTGCCAAGGAAATTAAACCTGTCCAACTCGG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005406575	(Get FASTA)	NCBI Sequence Viewer
	XP_013361046	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005406575 ⟸ XM_005406518

- Peptide Label:

isoform X1

- Sequence:

show sequence

MARVSAALRVYAVGAALLLLQLLRRCRGGFSPPVFCRQPDRVAVVTGGTDGIGYSTAKQLARLG
VHVIIAGNNEERAQQAVSRIKEETLNTKGMFLGKTTACQRFPSRWYPAPEQHFHTLGVEFLYCN
LASMKSIRQFVKNFKMKRLPLHVLVNNAGVMMVPQRKTEDGFEEHFGLNYLGHFLLTSLLLDSL
KESGSPGRSSRVVTVSSATHYVGELNLEDLQSSSCYSPHGAYARSKLALVMFSYHLQRLLEAQG
CHVTANVVDPGVVNTDLYKHVFWGTRLVQRILGWLLFKTPDEGAWTSVYAAVSPELEGLGGRYL
YNEKETKSLEVTYDQKLQQQLWARSCQMTGVTDVTRGTILD

hide sequence

RefSeq Acc Id:

XP_013361046 ⟸ XM_013505592

- Peptide Label:

isoform X2

- Sequence:

show sequence

MARVSAALRVYAVGAALLLLQLLRRCRGGFSPPVFCRQPDRVAVVTGGTDGIGYSTAKQLARLG
VHVIIAGNNEERAQQAVSRIKEETLNTKVEFLYCNLASMKSIRQFVKNFKMKRLPLHVLVNNAG
VMMVPQRKTEDGFEEHFGLNYLGHFLLTSLLLDSLKESGSPGRSSRVVTVSSATHYVGELNLED
LQSSSCYSPHGAYARSKLALVMFSYHLQRLLEAQGCHVTANVVDPGVVNTDLYKHVFWGTRLVQ
RILGWLLFKTPDEGAWTSVYAAVSPELEGLGGRYLYNEKETKSLEVTYDQKLQQQLWARSCQMT
GVTDVTRGTILD

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Dhrsx	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Dhrsx	dehydrogenase/reductase X-linked		dehydrogenase/reductase (SDR family) X-linked	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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