MIR7111 (microRNA 7111) - Rat Genome Database

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Gene: MIR7111 (microRNA 7111) Homo sapiens
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Symbol: MIR7111
Name: microRNA 7111
RGD ID: 8551618
HGNC Page HGNC
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-7111
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl635,470,508 - 35,470,579 (+)EnsemblGRCh38hg38GRCh38
GRCh38635,470,508 - 35,470,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37635,438,285 - 35,438,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map6p21.31NCBI
HuRef635,159,039 - 35,159,110 (+)NCBIHuRef
CHM1_1635,440,296 - 35,440,367 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22955976  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:99045
Count of gene targets:26101
Count of transcripts:70981
Interacting mature miRNAs:hsa-miR-7111-3p, hsa-miR-7111-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 26 19 20 11 212 11 80 22 41 18 49 46 2 1 5 2
Low 234 162 129 48 366 45 457 101 213 50 237 274 13 82 165 2
Below cutoff 61 54 28 13 26 5 75 52 64 6 28 14 8 33 42

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_106961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AL022721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000619751
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl635,470,508 - 35,470,579 (+)Ensembl
RefSeq Acc Id: NR_106961
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38635,470,508 - 35,470,579 (+)NCBI
HuRef635,159,039 - 35,159,110 (+)NCBI
CHM1_1635,440,296 - 35,440,367 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic

Additional Information

Database Acc Id Source(s)
COSMIC MIR7111 COSMIC
Ensembl Genes ENSG00000276712 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000619751 ENTREZGENE
GTEx ENSG00000276712 GTEx
HGNC ID HGNC:50073 ENTREZGENE
Human Proteome Map MIR7111 Human Proteome Map
miRBase MI0022962 ENTREZGENE
NCBI Gene MIR7111 ENTREZGENE
RNAcentral URS000075B456 RNACentral
  URS000075EE2D RNACentral
  URS000075EFAC RNACentral