MIR7113 (microRNA 7113) - Rat Genome Database

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Gene: MIR7113 (microRNA 7113) Homo sapiens
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Symbol: MIR7113
Name: microRNA 7113
RGD ID: 8550705
HGNC Page HGNC
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-7113
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1168,032,864 - 68,032,922 (+)EnsemblGRCh38hg38GRCh38
GRCh381168,032,864 - 68,032,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371167,800,331 - 67,800,389 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map11q13.2NCBI
HuRef1164,135,678 - 64,135,736 (+)NCBIHuRef
CHM1_11167,684,098 - 67,684,156 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22955976   PMID:33189141  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:72451
Count of gene targets:20490
Count of transcripts:52140
Interacting mature miRNAs:hsa-miR-7113-3p, hsa-miR-7113-5p
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium
Low 96 70 81 18 44 7 127 69 136 4 59 66 11 35 83
Below cutoff 13 25 15 5 7 4 35 31 45 2 7 3 1 11 24

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000621222
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1168,032,864 - 68,032,922 (+)Ensembl
RefSeq Acc Id: NR_106963
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381168,032,864 - 68,032,922 (+)NCBI
HuRef1164,135,678 - 64,135,736 (+)NCBI
CHM1_11167,684,098 - 67,684,156 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q13.2-13.3(chr11:67217264-69448598)x1 copy number loss See cases [RCV000135609] Chr11:67217264..69448598 [GRCh38]
Chr11:66984735..69263366 [GRCh37]
Chr11:66741311..68972547 [NCBI36]
Chr11:11q13.2-13.3
likely pathogenic
GRCh38/hg38 11q13.2-13.4(chr11:68031693-71593495)x1 copy number loss See cases [RCV000142138] Chr11:68031693..71593495 [GRCh38]
Chr11:67799160..71304541 [GRCh37]
Chr11:67555736..70982189 [NCBI36]
Chr11:11q13.2-13.4
likely pathogenic
GRCh38/hg38 11q13.2(chr11:67446153-68679073)x1 copy number loss See cases [RCV000052683] Chr11:67446153..68679073 [GRCh38]
Chr11:67213624..68446541 [GRCh37]
Chr11:66970200..68203117 [NCBI36]
Chr11:11q13.2
pathogenic
NM_002496.4(NDUFS8):c.110-11C>T single nucleotide variant not specified [RCV000419159] Chr11:68032912 [GRCh38]
Chr11:67800379 [GRCh37]
Chr11:11q13.2
likely benign

Additional Information

Database Acc Id Source(s)
COSMIC MIR7113 COSMIC
Ensembl Genes ENSG00000284293 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000621222 ENTREZGENE
GTEx ENSG00000284293 GTEx
HGNC ID HGNC:49947 ENTREZGENE
Human Proteome Map MIR7113 Human Proteome Map
miRBase MI0022964 ENTREZGENE
NCBI Gene MIR7113 ENTREZGENE
RNAcentral URS00007599A0 RNACentral
  URS000075D451 RNACentral
  URS000075DBAA RNACentral