Strit1 (small transmembrane regulator of ion transport 1) - Rat Genome Database

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Gene: Strit1 (small transmembrane regulator of ion transport 1) Rattus norvegicus
Analyze
Symbol: Strit1
Name: small transmembrane regulator of ion transport 1
RGD ID: 7663730
Description: Predicted to enable enzyme activator activity. Predicted to be involved in positive regulation of calcium ion import into sarcoplasmic reticulum; positive regulation of cardiac muscle cell contraction; and regulation of slow-twitch skeletal muscle fiber contraction. Predicted to act upstream of or within positive regulation of calcium ion import. Predicted to be located in sarcoplasmic reticulum membrane; INTERACTS WITH benzo[a]pyrene (ortholog); sunitinib (ortholog).
Type: ncrna (Ensembl: protein-coding)
RefSeq Status: VALIDATED
Previously known as: ENSRNOG00000066453; LOC102546391; uncharacterized LOC102546391
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82150,084,857 - 150,087,721 (-)NCBIGRCr8
mRatBN7.22147,935,219 - 147,938,083 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2147,935,222 - 147,938,083 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2154,629,554 - 154,632,416 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02152,679,003 - 152,681,865 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02147,311,691 - 147,314,553 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02154,030,401 - 154,033,265 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,030,237 - 154,033,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,418,567 - 173,421,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2142,221,795 - 142,224,659 (-)NCBICelera
Cytogenetic Map2q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Strit1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82150,084,857 - 150,087,721 (-)NCBIGRCr8
mRatBN7.22147,935,219 - 147,938,083 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2147,935,222 - 147,938,083 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2154,629,554 - 154,632,416 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02152,679,003 - 152,681,865 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02147,311,691 - 147,314,553 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02154,030,401 - 154,033,265 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,030,237 - 154,033,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,418,567 - 173,421,475 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2142,221,795 - 142,224,659 (-)NCBICelera
Cytogenetic Map2q31NCBI
STRIT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383155,290,227 - 155,293,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3155,290,227 - 155,293,683 (-)EnsemblGRCh38hg38GRCh38
GRCh373155,008,016 - 155,011,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map3q25.2NCBI
HuRef3152,402,230 - 152,405,698 (-)NCBIHuRef
CHM1_13154,971,058 - 154,974,543 (-)NCBICHM1_1
T2T-CHM13v2.03158,064,207 - 158,067,663 (-)NCBIT2T-CHM13v2.0
Strit1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,388,516 - 63,391,327 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl363,388,533 - 63,391,300 (-)EnsemblGRCm39 Ensembl
GRCm38363,481,095 - 63,483,906 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,481,112 - 63,483,879 (-)EnsemblGRCm38mm10GRCm38
Celera363,154,551 - 63,157,363 (-)NCBICelera
Cytogenetic Map3E1NCBI
STRIT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22153,203,629 - 153,209,586 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13153,208,359 - 153,214,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03152,346,768 - 152,351,244 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13160,398,665 - 160,402,152 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,399,367 - 160,402,051 (-)Ensemblpanpan1.1panPan2
STRIT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,131,218 - 49,134,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,131,221 - 49,134,942 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,006,134 - 49,027,054 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02349,764,376 - 49,785,339 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2349,764,379 - 49,768,122 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12349,350,344 - 49,371,236 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02349,400,356 - 49,421,263 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02349,683,533 - 49,704,426 (-)NCBIUU_Cfam_GSD_1.0
Strit1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560287,066,687 - 87,069,867 (+)NCBIHiC_Itri_2
STRIT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660418,116,308 - 8,120,073 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Strit1
14 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1549828Bp258Blood pressure QTL 2580.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2142323368150650069Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2112103657148076632Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2118111229149559726Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2104559726149559726Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 16 8 8 8
Low 17 1 1 1 2 3 7
Below cutoff 10 12 8 4 8 5 9 10 1

Sequence


RefSeq Acc Id: ENSRNOT00000078455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2154,030,237 - 154,033,351 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109971   ⟹   ENSRNOP00000088721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2147,935,222 - 147,938,083 (-)Ensembl
RefSeq Acc Id: NR_131133
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82150,084,857 - 150,087,721 (-)NCBI
mRatBN7.22147,935,219 - 147,938,083 (-)NCBI
Rnor_6.02154,030,401 - 154,033,265 (-)NCBI
Celera2142,221,795 - 142,224,659 (-)NCBI
Sequence:
Protein Sequences
Ensembl Protein ENSRNOP00000088721.1
RefSeq Acc Id: ENSRNOP00000088721   ⟸   ENSRNOT00000109971

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-52930 BioCyc
Ensembl Genes ENSRNOG00000052016 Ensembl
  ENSRNOG00000066453 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000109971 ENTREZGENE
  ENSRNOT00000109971.1 UniProtKB/TrEMBL
InterPro DWORF UniProtKB/TrEMBL
NCBI Gene LOC102546391 ENTREZGENE
PhenoGen Strit1 PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052016 RatGTEx
  ENSRNOG00000066453 RatGTEx
RNAcentral URS0000812187 RNACentral
  URS0000812194 RNACentral
UniProt A0A8I6A740_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-18 Strit1  small transmembrane regulator of ion transport 1  LOC102546391  uncharacterized LOC102546391  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-02 LOC102546391  uncharacterized LOC102546391  ENSRNOG00000066453    Data merged from RGD:150344253 737654 PROVISIONAL
2021-08-31 ENSRNOG00000066453        Symbol and Name status set to provisional 45752 PROVISIONAL
2013-12-18 LOC102546391  uncharacterized LOC102546391      Symbol and Name status set to provisional 70820 PROVISIONAL