Mir128-2 (microRNA 128-2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mir128-2 (microRNA 128-2) Rattus norvegicus
Analyze
Symbol: Mir128-2
Name: microRNA 128-2
RGD ID: 7489034
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; negative regulation of transport; and regulation of gene expression. Predicted to act upstream of or within cellular senescence; long-term synaptic potentiation; and negative regulation of gene expression. Orthologous to human MIR128-2 (microRNA 128-2); INTERACTS WITH cisplatin; paracetamol; aflatoxin B1 (ortholog).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-128-2
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28112,085,467 - 112,085,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8112,085,467 - 112,085,550 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8117,699,130 - 117,699,213 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08115,898,428 - 115,898,511 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08113,741,236 - 113,741,319 (-)NCBIRnor_WKY
Rnor_6.08120,378,945 - 120,379,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8120,378,945 - 120,379,028 (-)EnsemblRnor6.0rn6Rnor6.0
Celera8111,361,537 - 111,361,620 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14691248   PMID:15345052   PMID:16381832   PMID:17604727   PMID:17805466   PMID:20403161   PMID:24307102   PMID:25751060   PMID:25858512   PMID:30701536   PMID:31985779   PMID:32278027  
PMID:33373887   PMID:34296305  


Genomics

Comparative Map Data
Mir128-2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28112,085,467 - 112,085,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8112,085,467 - 112,085,550 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8117,699,130 - 117,699,213 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08115,898,428 - 115,898,511 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08113,741,236 - 113,741,319 (-)NCBIRnor_WKY
Rnor_6.08120,378,945 - 120,379,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8120,378,945 - 120,379,028 (-)EnsemblRnor6.0rn6Rnor6.0
Celera8111,361,537 - 111,361,620 (-)NCBICelera
Cytogenetic Map8q32NCBI
MIR128-2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38335,744,476 - 35,744,559 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl335,744,476 - 35,744,559 (+)EnsemblGRCh38hg38GRCh38
GRCh37335,785,968 - 35,786,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36335,760,971 - 35,761,054 (+)NCBINCBI36Build 36hg18NCBI36
Celera335,727,938 - 35,728,021 (+)NCBICelera
Cytogenetic Map3p22.3NCBI
HuRef335,727,088 - 35,727,171 (+)NCBIHuRef
CHM1_1335,736,007 - 35,736,090 (+)NCBICHM1_1
T2T-CHM13v2.0335,745,134 - 35,745,217 (+)NCBIT2T-CHM13v2.0
Mir128-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399111,947,704 - 111,947,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9111,947,704 - 111,947,779 (-)EnsemblGRCm39 Ensembl
GRCm389112,118,636 - 112,118,711 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9112,118,636 - 112,118,711 (-)EnsemblGRCm38mm10GRCm38
MGSCv379112,021,140 - 112,021,215 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera9111,847,023 - 111,847,098 (-)NCBICelera
Cytogenetic Map9F3NCBI
MIR128-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,826,463 - 5,826,520 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,826,449 - 5,826,532 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha235,866,881 - 5,866,938 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,106,256 - 6,106,313 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,106,242 - 6,106,325 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1235,927,155 - 5,927,212 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0236,073,741 - 6,073,798 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0236,061,221 - 6,061,278 (+)NCBIUU_Cfam_GSD_1.0
MIR128-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1321,038,442 - 21,038,525 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11321,038,445 - 21,038,524 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21322,859,191 - 22,859,270 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:12683
Count of gene targets:8554
Count of transcripts:9348
Interacting mature miRNAs:rno-miR-128-2-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system reproductive system appendage
High
Medium 4 4
Low 9 5 1 1 10 1 1
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053730
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8112,085,467 - 112,085,550 (-)Ensembl
Rnor_6.0 Ensembl8120,378,945 - 120,379,028 (-)Ensembl
RefSeq Acc Id: NR_031874
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28112,085,467 - 112,085,550 (-)NCBI
Rnor_6.08120,378,945 - 120,379,028 (-)NCBI
Celera8111,361,537 - 111,361,620 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7489034 AgrOrtholog
BioCyc Gene G2FUF-29007 BioCyc
Ensembl Genes ENSRNOG00000035607 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053730 ENTREZGENE
miRBase MI0000901 ENTREZGENE
NCBI Gene Mir128-2 ENTREZGENE
PhenoGen Mir128-2 PhenoGen
RNAcentral URS000024A59E RNACentral
  URS000062DC4A RNACentral
  URS000075D645 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir128-2  microRNA 128-2  Mir128-2  microRNA mir-128-2  Name updated 61478 APPROVED
2013-12-10 Mir128-2  microRNA mir-128-2      Symbol and Name status set to provisional 70820 PROVISIONAL