Mir1298 (microRNA 1298) - Rat Genome Database

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Gene: Mir1298 (microRNA 1298) Rattus norvegicus
Analyze
Symbol: Mir1298
Name: microRNA 1298
RGD ID: 7489010
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-1298
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X115,556,947 - 115,557,085 (+)NCBIGRCr8
mRatBN7.2X110,744,907 - 110,745,045 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX110,744,907 - 110,745,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX112,837,449 - 112,837,587 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X116,336,306 - 116,336,444 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X113,889,308 - 113,889,446 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X118,190,212 - 118,190,350 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX118,190,212 - 118,190,350 (+)EnsemblRnor6.0rn6Rnor6.0
CeleraX110,055,823 - 110,055,961 (+)NCBICelera
Cytogenetic MapXq34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:16381832   PMID:22605339   PMID:22908386   PMID:28762861   PMID:36781484  


Genomics

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:2768
Count of gene targets:2283
Count of transcripts:2445
Interacting mature miRNAs:rno-miR-1298
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

nervous system respiratory system
High
Medium
Low 10
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_106693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000063291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX110,744,907 - 110,745,045 (+)Ensembl
Rnor_6.0 EnsemblX118,190,212 - 118,190,350 (+)Ensembl
RefSeq Acc Id: NR_106693
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X115,556,947 - 115,557,085 (+)NCBI
mRatBN7.2X110,744,907 - 110,745,045 (+)NCBI
Rnor_6.0X118,190,212 - 118,190,350 (+)NCBI
CeleraX110,055,823 - 110,055,961 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-1447 BioCyc
Ensembl Genes ENSRNOG00000041538 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000063291 ENTREZGENE
miRBase MI0021845 ENTREZGENE
NCBI Gene Mir1298 ENTREZGENE
PhenoGen Mir1298 PhenoGen
RatGTEx ENSRNOG00000041538 RatGTEx
RNAcentral URS00003DF3AE RNACentral
  URS000075EBD2 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir1298  microRNA 1298  Mir1298  microRNA mir-1298  Name updated 61478 APPROVED
2013-12-10 Mir1298  microRNA mir-1298      Symbol and Name status set to provisional 70820 PROVISIONAL