Gene: KCNH6 (potassium voltage-gated channel subfamily H member 6) Homo sapiens
Symbol: KCNH6
Name: potassium voltage-gated channel subfamily H member 6
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: eag related protein 2; eag-related gene member 2; eag-related protein 2; ERG-2; ERG2; ether-a-go-go related gene potassium channel 2; ether-a-go-go-related gene potassium channel 2; ether-a-go-go-related protein 2; hERG-2; HERG2; Kv11.2; potassium channel, voltage gated eag related subfamily H, member 6; potassium voltage-gated channel, subfamily H (eag-related), member 6; voltage-gated potassium channel subunit Kv11.2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381763,523,334 - 63,548,977 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371761,600,695 - 61,626,338 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,954,427 - 58,980,070 (+)NCBINCBI36hg18NCBI36
Build 341758,954,426 - 58,980,070NCBI
Celera1755,988,522 - 56,014,428 (+)NCBI
Cytogenetic Map17q23.3NCBI
HuRef1756,966,852 - 56,992,787 (+)NCBIHuRef
CHM1_11761,664,820 - 61,690,751 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNH6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737542
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE