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Gene: PEAK1 (pseudopodium enriched atypical kinase 1) Homo sapiens
Symbol: PEAK1
Name: pseudopodium enriched atypical kinase 1
Description: This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: inactive tyrosine-protein kinase PEAK1; NKF3 kinase family member; pseudopodium enriched atypical kinase; pseudopodium-enriched atypical kinase 1; SGK269; sugen kinase 269; tyrosine-protein kinase SgK269
Mus musculus (house mouse) : Peak1 (pseudopodium-enriched atypical kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Peak1 (pseudopodium-enriched atypical kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Peak1 (pseudopodium enriched atypical kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PEAK1 (pseudopodium enriched atypical kinase 1)
Canis lupus familiaris (dog) : PEAK1 (pseudopodium enriched atypical kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Peak1 (pseudopodium enriched atypical kinase 1)
Sus scrofa (pig) : PEAK1 (pseudopodium enriched atypical kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381577,100,829 - 77,420,699 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371577,400,498 - 77,712,446 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361575,187,526 - 75,364,388 (-)NCBINCBI36hg18NCBI36
Celera1554,338,615 - 54,506,133 (-)NCBI
Cytogenetic Map15q24.3NCBI
HuRef1554,157,666 - 54,469,430 (-)NCBIHuRef
CHM1_11577,518,447 - 77,830,492 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PEAK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 7374592
Created: 2013-10-22
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.