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Gene: PRPS2 (phosphoribosyl pyrophosphate synthetase 2) Homo sapiens
Symbol: PRPS2
Name: phosphoribosyl pyrophosphate synthetase 2
Description: Exhibits identical protein binding activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to localize to the cytoplasm and ribose phosphate diphosphokinase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: phosphoribosyl pyrophosphate synthase II; PPRibP synthetase; PRS-II; PRSII; ribose-phosphate diphosphokinase 2; ribose-phosphate pyrophosphokinase 2; testicular secretory protein Li 41
Mus musculus (house mouse) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Canis lupus familiaris (dog) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Sus scrofa (pig) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Chlorocebus sabaeus (green monkey) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Heterocephalus glaber (naked mole-rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX12,791,355 - 12,824,222 (+)Ensembl
GRCh38X12,791,355 - 12,824,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X12,809,474 - 12,842,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,719,414 - 12,752,264 (+)NCBINCBI36hg18NCBI36
Build 34X12,569,187 - 12,601,996NCBI
CeleraX16,923,480 - 16,956,355 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX10,576,287 - 10,608,838 (+)NCBIHuRef
CHM1_1X12,839,890 - 12,872,768 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PRPS2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737326
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.