Scn1b (sodium channel, voltage-gated, type I, beta) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Scn1b (sodium channel, voltage-gated, type I, beta) Mus musculus
Analyze
Symbol: Scn1b
Name: sodium channel, voltage-gated, type I, beta
RGD ID: 737154
MGI Page MGI
Description: Enables sodium channel inhibitor activity. Involved in several processes, including membrane depolarization during cardiac muscle cell action potential; regulation of sodium ion transport; and regulation of ventricular cardiac muscle cell membrane repolarization. Acts upstream of or within several processes, including corticospinal neuron axon guidance; neuronal action potential propagation; and positive regulation of neuron projection development. Located in T-tubule; intercalated disc; and node of Ranvier. Part of voltage-gated sodium channel complex. Is expressed in heart and telencephalon. Used to study generalized epilepsy with febrile seizures plus. Human ortholog(s) of this gene implicated in Brugada syndrome 5; developmental and epileptic encephalopathy 52; familial atrial fibrillation; and generalized epilepsy with febrile seizures plus 1. Orthologous to human SCN1B (sodium voltage-gated channel beta subunit 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: sodium channel regulatory subunit beta-1; sodium channel subunit beta-1; sodium channel, voltage-gated, type I, beta polypeptide
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,815,949 - 30,826,436 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,815,949 - 30,826,428 (-)EnsemblGRCm39 Ensembl
GRCm38731,116,524 - 31,127,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl731,116,524 - 31,127,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,901,543 - 31,911,964 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,825,284 - 30,835,705 (-)NCBIMGSCv36mm8
Celera725,685,753 - 25,696,176 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-trans-(S)-allethrin  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
alpha-Zearalanol  (ISO)
amiodarone  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
carmustine  (ISO)
casticin  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
cobalt dichloride  (ISO)
corn oil  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
cyfluthrin  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
dibenz[a,h]anthracene  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
fenpropathrin  (ISO)
fenvalerate  (ISO)
flutamide  (ISO)
furan  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenytoin  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
prostaglandin F2alpha  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium atom  (ISO)
sodium fluoride  (EXP)
testosterone  (ISO)
tetrodotoxin  (ISO)
tioguanine  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lidocaine pharmacokinetics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genes encoding the beta 1 subunit of voltage-dependent Na+ channel in rat, mouse and human contain conserved introns. Dib-Hajj SD and Waxman SG, FEBS Lett 1995 Dec 27;377(3):485-8.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Shortening and intracellular Ca2+ in ventricular myocytes and expression of genes encoding cardiac muscle proteins in early onset type 2 diabetic Goto-Kakizaki rats. Salem KA, etal., Exp Physiol. 2012 May 11.
Additional References at PubMed
PMID:7690558   PMID:8757791   PMID:8812484   PMID:8889548   PMID:9013777   PMID:9403069   PMID:9721701   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932  
PMID:15007009   PMID:15102918   PMID:15272007   PMID:15452131   PMID:15489334   PMID:15664175   PMID:15721864   PMID:15746173   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16985003  
PMID:17868089   PMID:17884088   PMID:18178574   PMID:18354028   PMID:18988673   PMID:19228957   PMID:19710327   PMID:20133873   PMID:20573896   PMID:20628201   PMID:21511879   PMID:21555511  
PMID:21873635   PMID:22007171   PMID:22348965   PMID:22397033   PMID:22539834   PMID:23090990   PMID:23277545   PMID:23291792   PMID:23542581   PMID:24581800   PMID:24662403   PMID:24729314  
PMID:24747835   PMID:25253298   PMID:25421039   PMID:25426816   PMID:25772295   PMID:25826454   PMID:26060908   PMID:26129877   PMID:26541940   PMID:26877851   PMID:27277800   PMID:30128323  
PMID:30175250   PMID:30996233   PMID:32503841   PMID:32979291   PMID:33411695   PMID:34321999   PMID:35364055   PMID:35394857   PMID:35603785   PMID:36257954   PMID:36808153   PMID:37264112  
PMID:37845033   PMID:38355793   PMID:39120465  


Genomics

Comparative Map Data
Scn1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,815,949 - 30,826,436 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,815,949 - 30,826,428 (-)EnsemblGRCm39 Ensembl
GRCm38731,116,524 - 31,127,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl731,116,524 - 31,127,003 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,901,543 - 31,911,964 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,825,284 - 30,835,705 (-)NCBIMGSCv36mm8
Celera725,685,753 - 25,696,176 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.3NCBI
SCN1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,030,470 - 35,040,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,030,470 - 35,040,449 (+)EnsemblGRCh38hg38GRCh38
GRCh371935,521,374 - 35,531,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,213,374 - 40,223,193 (+)NCBINCBI36Build 36hg18NCBI36
Build 341940,213,373 - 40,217,014NCBI
Celera1932,237,030 - 32,244,951 (+)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1932,031,550 - 32,039,386 (+)NCBIHuRef
CHM1_11935,523,533 - 35,533,294 (+)NCBICHM1_1
T2T-CHM13v2.01937,575,088 - 37,585,067 (+)NCBIT2T-CHM13v2.0
Scn1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,481,298 - 95,491,211 (-)NCBIGRCr8
mRatBN7.2186,353,917 - 86,363,820 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,353,917 - 86,363,739 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,774,394 - 91,784,282 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,240,553 - 100,250,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,532,687 - 93,542,575 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,550,738 - 89,560,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,550,738 - 89,560,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,705,285 - 90,715,016 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,162,254 - 86,172,128 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,240,364 - 86,250,239 (-)NCBI
Celera180,722,797 - 80,732,619 (-)NCBICelera
Cytogenetic Map1q21NCBI
Scn1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,375,157 - 4,383,502 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554684,375,517 - 4,383,383 (+)NCBIChiLan1.0ChiLan1.0
SCN1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,041,639 - 41,051,647 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,024,053 - 43,034,048 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01931,974,499 - 31,984,488 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,714,949 - 40,724,052 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,711,281 - 40,724,052 (+)Ensemblpanpan1.1panPan2
SCN1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,504,428 - 117,510,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,503,828 - 117,511,727 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,904,982 - 116,912,817 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,101,274 - 118,110,870 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,101,277 - 118,109,849 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,664,454 - 117,672,298 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,289,863 - 117,297,724 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,346,453 - 118,354,295 (-)NCBIUU_Cfam_GSD_1.0
Scn1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,450,449 - 10,457,966 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365701,186,711 - 1,195,388 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365701,187,916 - 1,195,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCN1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,597,482 - 44,607,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,597,461 - 44,607,488 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,022,785 - 40,032,360 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCN1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1629,962,993 - 29,972,845 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl629,962,843 - 29,973,325 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660737,732,359 - 7,742,427 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scn1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,439,600 - 8,450,179 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247948,439,609 - 8,449,731 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scn1b
702 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:341
Count of miRNA genes:213
Interacting mature miRNAs:237
Transcripts:ENSMUST00000098548
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse

Markers in Region
Scn1b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7B1UniSTS
cM Map710.0UniSTS
U85786  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38731,116,590 - 31,116,731UniSTSGRCm38
MGSCv37731,901,609 - 31,901,750UniSTSGRCm37
Celera725,685,819 - 25,685,960UniSTS
Cytogenetic Map7B1UniSTS
cM Map710.0UniSTS
Whitehead/MRC_RH7419.49UniSTS
PMC15797P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38731,116,698 - 31,116,913UniSTSGRCm38
MGSCv37731,901,717 - 31,901,932UniSTSGRCm37
Celera725,685,927 - 25,686,142UniSTS
Cytogenetic Map7B1UniSTS
cM Map710.0UniSTS
Scn1b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7B1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000098548   ⟹   ENSMUSP00000096148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl730,815,949 - 30,826,428 (-)Ensembl
GRCm38.p6 Ensembl731,116,524 - 31,127,003 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl730,817,131 - 30,824,845 (-)Ensembl
GRCm38.p6 Ensembl731,117,706 - 31,125,420 (-)Ensembl
Ensembl Acc Id: ENSMUST00000211945   ⟹   ENSMUSP00000148295
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl730,815,949 - 30,826,269 (-)Ensembl
GRCm38.p6 Ensembl731,116,524 - 31,126,844 (-)Ensembl
RefSeq Acc Id: NM_001402334   ⟹   NP_001389263
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39730,815,949 - 30,826,191 (-)NCBI
RefSeq Acc Id: NM_011322   ⟹   NP_035452
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39730,815,949 - 30,826,436 (-)NCBI
GRCm38731,116,524 - 31,127,023 (-)NCBI
MGSCv37731,901,543 - 31,911,964 (-)RGD
Celera725,685,753 - 25,696,176 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035452   ⟸   NM_011322
- Peptide Label: isoform 1 precursor
- UniProtKB: P97952 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000148295   ⟸   ENSMUST00000211945
Ensembl Acc Id: ENSMUSP00000096148   ⟸   ENSMUST00000098548
RefSeq Acc Id: NP_001389263   ⟸   NM_001402334
- Peptide Label: isoform 2
Protein Domains
Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97952-F1-model_v2 AlphaFold P97952 1-218 view protein structure

Promoters
RGD ID:8663579
Promoter ID:EPDNEW_M9820
Type:initiation region
Name:Scn1b_2
Description:Mus musculus sodium channel, voltage-gated, type I, beta , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9821  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38731,126,766 - 31,126,826EPDNEW
RGD ID:8663581
Promoter ID:EPDNEW_M9821
Type:initiation region
Name:Scn1b_1
Description:Mus musculus sodium channel, voltage-gated, type I, beta , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M9820  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38731,127,009 - 31,127,069EPDNEW
RGD ID:6848205
Promoter ID:MM_ACW:44193
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Brain
Transcripts:SCN1B.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36731,910,216 - 31,910,917 (-)MPROMDB
RGD ID:6841983
Promoter ID:MM_KWN:49890
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000098548,   NM_011322
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36731,912,016 - 31,912,902 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98247 AgrOrtholog
Ensembl Genes ENSMUSG00000019194 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098548 ENTREZGENE
  ENSMUST00000098548.8 UniProtKB/Swiss-Prot
  ENSMUST00000211945.2 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  Na_channel_b1/b3 UniProtKB/Swiss-Prot
KEGG Report mmu:20266 UniProtKB/Swiss-Prot
MGD MGI:98247 ENTREZGENE
NCBI Gene 20266 ENTREZGENE
PANTHER PTHR10546 UniProtKB/Swiss-Prot
  PTHR10546:SF2 UniProtKB/Swiss-Prot
Pfam V-set UniProtKB/Swiss-Prot
PharmGKB SCN1B RGD
PhenoGen Scn1b PhenoGen
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt P97952 ENTREZGENE, UniProtKB/Swiss-Prot