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Gene: CD3D (CD3d molecule) Homo sapiens
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Symbol: CD3D
Name: CD3d molecule
Description: Exhibits identical protein binding activity; protein heterodimerization activity; and transcription coactivator activity. Involved in T cell differentiation and positive regulation of transcription by RNA polymerase II. Localizes to T cell receptor complex. Implicated in primary immunodeficiency disease and severe combined immunodeficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cd3 antigen delta polypeptide; CD3 antigen, delta subunit; CD3 delta; CD3-DELTA; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule, delta (CD3-TCR complex); IMD19; OKT3, delta chain; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain; T3D
Orthologs:
Mus musculus (house mouse) : Cd3d (CD3 antigen, delta polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd3d (CD3d molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd3d (CD3d molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD3D (CD3d molecule)
Canis lupus familiaris (dog) : CD3D (CD3d molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd3d (CD3d molecule)
Sus scrofa (pig) : CD3D (CD3d molecule)
Chlorocebus sabaeus (African green monkey) : CD3D (CD3d molecule)
Heterocephalus glaber (naked mole-rat) : Cd3d (CD3d molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11118,338,954 - 118,342,744 (-)EnsemblGRCh38hg38GRCh38
GRCh3811118,338,954 - 118,342,705 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,209,789 - 118,213,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,714,999 - 117,718,669 (-)NCBINCBI36hg18NCBI36
Build 3411117,710,474 - 117,718,533NCBI
Celera11115,367,658 - 115,371,328 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,143,683 - 114,147,356 (-)NCBIHuRef
CHM1_111118,096,225 - 118,099,892 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CD3D
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736987
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.