Trim17 (tripartite motif-containing 17) - Rat Genome Database
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Gene: Trim17 (tripartite motif-containing 17) Mus musculus
Analyze
Symbol: Trim17
Name: tripartite motif-containing 17
RGD ID: 736910
MGI Page MGI
Description: Orthologous to human TRIM17 (tripartite motif containing 17); INTERACTS WITH 1,2-dimethylhydrazine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase TRIM17; ring finger protein 16; RING-type E3 ubiquitin transferase TRIM17; Rnf; Rnf16; ter; terf; tripartite motif protein 17; tripartite motif protein TRIM17; tripartite motif-containing protein 17
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,845,511 - 58,863,923 (+)NCBIGRCm39mm39
GRCm39 Ensembl1158,845,511 - 58,863,924 (+)Ensembl
GRCm381158,954,671 - 58,973,075 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,954,685 - 58,973,098 (+)EnsemblGRCm38mm10GRCm38
MGSCv371158,777,283 - 58,785,231 (+)NCBIGRCm37mm9NCBIm37
MGSCv361158,779,976 - 58,787,924 (+)NCBImm8
Celera1163,730,120 - 63,738,057 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

References

Additional References at PubMed
PMID:10349636   PMID:10894938   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:15489334   PMID:15618518   PMID:16141072   PMID:16141073   PMID:19358823   PMID:20559321  
PMID:21677750   PMID:21873635   PMID:22976837   PMID:25215946   PMID:31201419  


Genomics

Comparative Map Data
Trim17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,845,511 - 58,863,923 (+)NCBIGRCm39mm39
GRCm39 Ensembl1158,845,511 - 58,863,924 (+)Ensembl
GRCm381158,954,671 - 58,973,075 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,954,685 - 58,973,098 (+)EnsemblGRCm38mm10GRCm38
MGSCv371158,777,283 - 58,785,231 (+)NCBIGRCm37mm9NCBIm37
MGSCv361158,779,976 - 58,787,924 (+)NCBImm8
Celera1163,730,120 - 63,738,057 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
TRIM17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1228,407,935 - 228,416,861 (-)EnsemblGRCh38hg38GRCh38
GRCh381228,406,877 - 228,416,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371228,595,636 - 228,604,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,662,264 - 226,670,977 (-)NCBINCBI36hg18NCBI36
Build 341224,902,474 - 224,911,041NCBI
Celera1201,785,592 - 201,794,538 (-)NCBI
Cytogenetic Map1q42.13NCBI
HuRef1199,110,231 - 199,119,178 (-)NCBIHuRef
CHM1_11229,867,960 - 229,876,895 (-)NCBICHM1_1
Trim17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21043,743,111 - 43,750,929 (+)NCBI
Rnor_6.0 Ensembl1045,297,937 - 45,314,837 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01045,307,007 - 45,314,823 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01045,059,659 - 45,071,507 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,255,305 - 45,263,207 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,268,911 - 45,276,911 (+)NCBI
Celera1043,009,464 - 43,017,279 (+)NCBICelera
Cytogenetic Map10q22NCBI
Trim17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955581107,251 - 113,907 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955581107,251 - 113,907 (+)NCBIChiLan1.0ChiLan1.0
TRIM17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11209,020,002 - 209,029,967 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1209,020,655 - 209,029,965 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01203,808,933 - 203,818,936 (-)NCBIMhudiblu_PPA_v0panPan3
TRIM17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl14634,060 - 647,431 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.114633,767 - 639,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Trim17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493713521,149 - 28,188 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl251,725,007 - 51,732,041 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1251,726,854 - 51,732,075 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRIM17
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,312,737 - 1,322,058 (+)NCBI

Position Markers
D11Mit369  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,969,991 - 58,970,113UniSTSGRCm38
MGSCv371158,783,493 - 58,783,615UniSTSGRCm37
Celera1163,736,319 - 63,736,441UniSTS
Cytogenetic Map11B1.2-B1.3UniSTS
cM Map1131.5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1343
Count of miRNA genes:487
Interacting mature miRNAs:574
Transcripts:ENSMUST00000047697, ENSMUST00000075141
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000047697   ⟹   ENSMUSP00000037248
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1158,954,685 - 58,973,098 (+)Ensembl
RefSeq Acc Id: ENSMUST00000075141   ⟹   ENSMUSP00000074639
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1158,963,802 - 58,973,098 (+)Ensembl
RefSeq Acc Id: NM_031172   ⟹   NP_112449
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,854,607 - 58,863,901 (+)NCBI
GRCm381158,963,781 - 58,973,075 (+)NCBI
MGSCv371158,777,283 - 58,785,231 (+)RGD
Celera1163,730,120 - 63,738,057 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006533811   ⟹   XP_006533874
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,845,659 - 58,862,563 (+)NCBI
GRCm381158,954,833 - 58,971,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006533812   ⟹   XP_006533875
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,854,715 - 58,863,923 (+)NCBI
GRCm381158,963,891 - 58,971,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011249157   ⟹   XP_011247459
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,845,511 - 58,862,563 (+)NCBI
GRCm381158,954,671 - 58,971,737 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_112449   ⟸   NM_031172
- UniProtKB: Q7TPM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006533874   ⟸   XM_006533811
- Peptide Label: isoform X1
- UniProtKB: Q7TPM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006533875   ⟸   XM_006533812
- Peptide Label: isoform X1
- UniProtKB: Q7TPM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011247459   ⟸   XM_011249157
- Peptide Label: isoform X1
- UniProtKB: Q7TPM3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000037248   ⟸   ENSMUST00000047697
RefSeq Acc Id: ENSMUSP00000074639   ⟸   ENSMUST00000075141
Protein Domains
B box-type   B30.2/SPRY   RING-type

Promoters
RGD ID:6821091
Promoter ID:MM_KWN:7608
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000047697,   NM_206882
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361158,767,959 - 58,768,459 (-)MPROMDB
RGD ID:8674780
Promoter ID:EPDNEW_M15420
Type:multiple initiation site
Name:Trim17_1
Description:Mus musculus tripartite motif-containing 17 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15422  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381158,954,685 - 58,954,745EPDNEW
RGD ID:8674782
Promoter ID:EPDNEW_M15422
Type:initiation region
Name:Trim17_2
Description:Mus musculus tripartite motif-containing 17 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15420  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381158,963,797 - 58,963,857EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1861440 AgrOrtholog
Ensembl Genes ENSMUSG00000036964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000037248 UniProtKB/TrEMBL
  ENSMUSP00000074639 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000047697 UniProtKB/TrEMBL
  ENSMUST00000075141 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/Swiss-Prot
  B30.2/SPRY_sf UniProtKB/Swiss-Prot
  Butyrophylin_SPRY UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  PRY UniProtKB/Swiss-Prot
  SPRY_dom UniProtKB/Swiss-Prot
  TRIM17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIM17_PRY/SPRY UniProtKB/Swiss-Prot
  Znf-RING_LisH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56631 UniProtKB/Swiss-Prot
MGD MGI:1861440 ENTREZGENE
NCBI Gene 56631 ENTREZGENE
PANTHER PTHR24103:SF397 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SPRY UniProtKB/Swiss-Prot
  zf-B_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trim17 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot
PROSITE B302_SPRY UniProtKB/Swiss-Prot
  ZF_BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRY UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A2AB81_MOUSE UniProtKB/TrEMBL
  Q7TPM3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A2AB82 UniProtKB/Swiss-Prot
  Q99PP8 UniProtKB/Swiss-Prot