Homer2 (homer scaffolding protein 2) - Rat Genome Database

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Gene: Homer2 (homer scaffolding protein 2) Mus musculus
Analyze
Symbol: Homer2
Name: homer scaffolding protein 2
RGD ID: 736904
MGI Page MGI
Description: Enables actin binding activity and synaptic receptor adaptor activity. Involved in sensory perception of sound. Acts upstream of or within behavioral response to cocaine; calcium-mediated signaling using intracellular calcium source; and regulation of G protein-coupled receptor signaling pathway. Located in apical part of cell; cytoplasm; and stereocilium tip. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including central nervous system; cranial nerve; jaw; sensory organ; and tongue. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 68. Orthologous to human HOMER2 (homer scaffold protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9330120H11Rik; AW539445; CP; CPD; Cup; cupidin; homer homolog 2; homer protein homolog 2; homer, neuronal immediate early gene, 2; homer-2; VASP/Ena-related gene up-regulated during seizure and LTP 2; Ves; Vesl-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,250,229 - 81,356,673 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,250,229 - 81,357,275 (-)EnsemblGRCm39 Ensembl
GRCm38781,600,481 - 81,706,925 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,600,481 - 81,707,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv37788,745,367 - 88,851,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36781,483,228 - 81,580,639 (-)NCBIMGSCv36mm8
Celera779,009,788 - 79,104,812 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2,4-trimethylbenzene  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
alachlor  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
CGP 52608  (ISO)
chlordecone  (EXP)
cisplatin  (ISO)
cocaine  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
genistein  (ISO)
glyphosate  (ISO)
GW 4064  (EXP)
Licochalcone B  (ISO)
maneb  (EXP)
N,N-diethyl-m-toluamide  (ISO)
ozone  (EXP)
paracetamol  (EXP)
paraquat  (EXP,ISO)
parathion  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (ISO)
phenylmercury acetate  (ISO)
phosgene  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
tamoxifen  (ISO)
tebuconazole  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
triclosan  (ISO)
undecane  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Xiao B, etal., Neuron 1998 Oct;21(4):707-16.
Additional References at PubMed
PMID:9808459   PMID:10349636   PMID:10493740   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11491285   PMID:12477932   PMID:12860966   PMID:15116392   PMID:15294147   PMID:15545022  
PMID:16011574   PMID:16011579   PMID:16049182   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16959763   PMID:17015433   PMID:17386922   PMID:17553998   PMID:17568396   PMID:18218901  
PMID:18287559   PMID:18387811   PMID:18603407   PMID:20807241   PMID:21267068   PMID:21873635   PMID:22561452   PMID:23076792   PMID:23658151   PMID:23911326   PMID:24427155   PMID:24530450  
PMID:25049230   PMID:25816005   PMID:25916683   PMID:26426435   PMID:27023172   PMID:27507650   PMID:28671696   PMID:28706196   PMID:28728878   PMID:29109058   PMID:31319381   PMID:32070057  
PMID:34118975   PMID:34321999   PMID:34788607   PMID:35008503   PMID:36604605   PMID:37758766  


Genomics

Comparative Map Data
Homer2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,250,229 - 81,356,673 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,250,229 - 81,357,275 (-)EnsemblGRCm39 Ensembl
GRCm38781,600,481 - 81,706,925 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl781,600,481 - 81,707,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv37788,745,367 - 88,851,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36781,483,228 - 81,580,639 (-)NCBIMGSCv36mm8
Celera779,009,788 - 79,104,812 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.71NCBI
HOMER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381582,834,661 - 82,986,157 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1582,836,946 - 82,986,153 (-)EnsemblGRCh38hg38GRCh38
GRCh371583,517,735 - 83,621,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361581,314,789 - 81,412,477 (-)NCBINCBI36Build 36hg18NCBI36
Build 341581,314,788 - 81,412,477NCBI
Celera1560,965,171 - 61,062,906 (+)NCBICelera
Cytogenetic Map15q25.2NCBI
HuRef1559,787,302 - 59,884,988 (-)NCBIHuRef
CHM1_11583,259,957 - 83,363,087 (-)NCBICHM1_1
T2T-CHM13v2.01580,701,241 - 80,850,554 (-)NCBIT2T-CHM13v2.0
Homer2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,968,207 - 145,069,022 (-)NCBIGRCr8
mRatBN7.21135,558,977 - 135,659,780 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,567,414 - 135,659,772 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,488,882 - 143,581,178 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01150,658,320 - 150,750,396 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,564,822 - 143,658,186 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01143,443,300 - 143,535,579 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1143,443,300 - 143,535,583 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01144,387,025 - 144,478,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,827,128 - 137,933,089 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,905,533 - 138,012,215 (-)NCBI
Celera1127,618,673 - 127,711,006 (-)NCBICelera
Cytogenetic Map1q31NCBI
Homer2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541613,741,161 - 13,818,060 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541613,671,115 - 13,828,413 (+)NCBIChiLan1.0ChiLan1.0
HOMER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21672,906,093 - 73,051,976 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11577,066,987 - 77,212,497 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01562,617,905 - 62,762,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11580,731,863 - 80,876,442 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1580,737,570 - 80,784,729 (-)Ensemblpanpan1.1panPan2
Homer2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640128,699,719 - 128,836,080 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648317,507,533 - 17,539,105 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648317,500,962 - 17,634,804 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOMER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl752,001,579 - 52,096,828 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1752,001,253 - 52,104,426 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2757,489,011 - 57,584,450 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOMER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1292,667,718 - 2,810,238 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl292,706,134 - 2,803,372 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605944,281,540 - 44,425,488 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Homer2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476818,635,283 - 18,721,984 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476818,626,353 - 18,751,279 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Homer2
3273 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7170
Count of miRNA genes:951
Interacting mature miRNAs:1408
Transcripts:ENSMUST00000026922, ENSMUST00000098326
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse

Markers in Region
AW539445  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,609,516 - 81,609,655UniSTSGRCm38
MGSCv37788,754,402 - 88,754,541UniSTSGRCm37
Celera779,018,827 - 79,018,966UniSTS
Cytogenetic Map7D3UniSTS
Whitehead/MRC_RH7761.48UniSTS
AB017136  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,610,072 - 81,610,182UniSTSGRCm38
MGSCv37788,754,958 - 88,755,068UniSTSGRCm37
Celera779,019,383 - 79,019,493UniSTS
Cytogenetic Map7D3UniSTS
Whitehead/MRC_RH7761.44UniSTS
Homer2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,609,783 - 81,610,021UniSTSGRCm38
Celera779,019,094 - 79,019,332UniSTS
Cytogenetic Map7D3UniSTS
cM Map745.71UniSTS
Homer2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38781,609,741 - 81,610,138UniSTSGRCm38
Celera779,019,052 - 79,019,449UniSTS
Cytogenetic Map7D3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001164087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA790874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB017136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC130538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG076134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ083069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV657327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026922   ⟹   ENSMUSP00000026922
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,259,478 - 81,356,692 (-)Ensembl
GRCm38.p6 Ensembl781,609,730 - 81,706,944 (-)Ensembl
RefSeq Acc Id: ENSMUST00000098326   ⟹   ENSMUSP00000095931
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,250,229 - 81,342,713 (-)Ensembl
GRCm38.p6 Ensembl781,600,481 - 81,692,965 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,268,456 - 81,356,534 (-)Ensembl
GRCm38.p6 Ensembl781,618,708 - 81,706,786 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207289
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,273,315 - 81,356,673 (-)Ensembl
GRCm38.p6 Ensembl781,623,567 - 81,706,925 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207371   ⟹   ENSMUSP00000147030
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,259,478 - 81,357,275 (-)Ensembl
GRCm38.p6 Ensembl781,609,730 - 81,707,527 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207983   ⟹   ENSMUSP00000146787
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,259,478 - 81,356,557 (-)Ensembl
GRCm38.p6 Ensembl781,609,730 - 81,706,809 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,264,100 - 81,268,653 (-)Ensembl
GRCm38.p6 Ensembl781,614,352 - 81,618,905 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,299,300 - 81,342,677 (-)Ensembl
GRCm38.p6 Ensembl781,649,552 - 81,692,929 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208937   ⟹   ENSMUSP00000146521
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,262,073 - 81,342,635 (-)Ensembl
GRCm38.p6 Ensembl781,612,325 - 81,692,887 (-)Ensembl
RefSeq Acc Id: NM_001164086   ⟹   NP_001157558
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,250,229 - 81,356,673 (-)NCBI
GRCm38781,600,481 - 81,706,925 (-)ENTREZGENE
MGSCv37788,745,367 - 88,851,811 (-)RGD
Celera779,009,788 - 79,104,812 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001164087   ⟹   NP_001157559
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,250,229 - 81,342,713 (-)NCBI
GRCm38781,600,481 - 81,692,965 (-)NCBI
MGSCv37788,745,367 - 88,851,811 (-)RGD
Celera779,009,788 - 79,104,812 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011983   ⟹   NP_036113
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,250,229 - 81,356,673 (-)NCBI
GRCm38781,600,481 - 81,706,925 (-)ENTREZGENE
MGSCv37788,745,367 - 88,851,811 (-)RGD
Celera779,009,788 - 79,104,812 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540909   ⟹   XP_006540972
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,250,229 - 81,342,672 (-)NCBI
GRCm38781,600,481 - 81,692,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242611   ⟹   XP_030098471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,250,229 - 81,338,332 (-)NCBI
GRCm38781,600,481 - 81,688,591 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_036113   ⟸   NM_011983
- Peptide Label: isoform 1
- UniProtKB: O89025 (UniProtKB/Swiss-Prot),   Q9Z0E4 (UniProtKB/Swiss-Prot),   Q9QWW1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157559   ⟸   NM_001164087
- Peptide Label: isoform 3
- UniProtKB: E9Q4F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157558   ⟸   NM_001164086
- Peptide Label: isoform 2
- UniProtKB: Q9QWW1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540972   ⟸   XM_006540909
- Peptide Label: isoform X1
- UniProtKB: E9Q4F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030098471   ⟸   XM_030242611
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000026922   ⟸   ENSMUST00000026922
RefSeq Acc Id: ENSMUSP00000146521   ⟸   ENSMUST00000208937
RefSeq Acc Id: ENSMUSP00000147030   ⟸   ENSMUST00000207371
RefSeq Acc Id: ENSMUSP00000146787   ⟸   ENSMUST00000207983
RefSeq Acc Id: ENSMUSP00000095931   ⟸   ENSMUST00000098326
Protein Domains
WH1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QWW1-F1-model_v2 AlphaFold Q9QWW1 1-354 view protein structure

Promoters
RGD ID:8664631
Promoter ID:EPDNEW_M10347
Type:initiation region
Name:Homer2_1
Description:Mus musculus homer scaffolding protein 2 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38781,706,916 - 81,706,976EPDNEW
RGD ID:6842347
Promoter ID:MM_KWN:51352
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000026922,   NM_001164086,   UC009ICJ.1,   UC009ICK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36788,851,556 - 88,852,056 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1347354 AgrOrtholog
Ensembl Genes ENSMUSG00000025813 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026922 ENTREZGENE
  ENSMUST00000026922.15 UniProtKB/Swiss-Prot
  ENSMUST00000098326 ENTREZGENE
  ENSMUST00000098326.3 UniProtKB/TrEMBL
  ENSMUST00000207371.2 UniProtKB/TrEMBL
  ENSMUST00000207983 ENTREZGENE
  ENSMUST00000207983.2 UniProtKB/Swiss-Prot
  ENSMUST00000208937.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1700 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Homer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homer_EVH1 UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26557 UniProtKB/Swiss-Prot
MGD MGI:1347354 ENTREZGENE
NCBI Gene 26557 ENTREZGENE
PANTHER HOMER PROTEIN HOMOLOG 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10918 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Homer2 PhenoGen
PROSITE WH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WH1 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tropomyosin UniProtKB/TrEMBL
UniProt A0A140LHR9_MOUSE UniProtKB/TrEMBL
  A0A140LJ06_MOUSE UniProtKB/TrEMBL
  E9Q4F9 ENTREZGENE, UniProtKB/TrEMBL
  HOME2_MOUSE UniProtKB/Swiss-Prot
  O89025 ENTREZGENE
  Q8BGC8_MOUSE UniProtKB/TrEMBL
  Q8CFI9_MOUSE UniProtKB/TrEMBL
  Q9CTG4_MOUSE UniProtKB/TrEMBL
  Q9QWW1 ENTREZGENE
  Q9Z0E4 ENTREZGENE
UniProt Secondary O89025 UniProtKB/Swiss-Prot
  Q9Z0E4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Homer2  homer scaffolding protein 2    homer homolog 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED