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Gene: Slc5a7 (solute carrier family 5 (choline transporter), member 7) Mus musculus
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Symbol: Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
Description: Exhibits choline binding activity and choline transmembrane transporter activity. Involved in several processes, including acetylcholine biosynthetic process; chemical synaptic transmission; and choline transport. Localizes to the neuronal cell body and plasma membrane. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20 and distal hereditary motor neuronopathy type 7A. Is expressed in several structures, including central nervous system and diaphragm. Orthologous to human SLC5A7 (solute carrier family 5 member 7); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH [6]-Shogaol; cerium trichloride; chlorpyrifos.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CHT; CHT1; hemicholinium-3-sensitive choline transporter; high affinity choline transporter 1; solute carrier family 5 member 7
Orthologs:
Homo sapiens (human) : SLC5A7 (solute carrier family 5 member 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc5a7 (solute carrier family 5 member 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc5a7 (solute carrier family 5 member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC5A7 (solute carrier family 5 member 7)
Canis lupus familiaris (dog) : SLC5A7 (solute carrier family 5 member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc5a7 (solute carrier family 5 member 7)
Sus scrofa (pig) : SLC5A7 (solute carrier family 5 member 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381754,273,590 - 54,299,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371754,412,915 - 54,438,359 (-)NCBIGRCm37mm9NCBIm37
MGSCv361753,749,658 - 53,773,230 (-)NCBImm8
Celera1757,690,527 - 57,715,838 (-)NCBICelera
Cytogenetic Map17 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Slc5a7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736894
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.