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Gene: Slc5a7 (solute carrier family 5 (choline transporter), member 7) Mus musculus
Symbol: Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
RGD ID: 736894
Description: Exhibits choline binding activity and choline transmembrane transporter activity. Involved in several processes, including acetylcholine biosynthetic process; chemical synaptic transmission; and choline transport. Localizes to neuronal cell body and plasma membrane. Is expressed in several structures, including central nervous system and diaphragm. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20 and distal hereditary motor neuronopathy type 7A. Orthologous to human SLC5A7 (solute carrier family 5 member 7); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH 4,4'-sulfonyldiphenol; [6]-Shogaol; cerium trichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CHT; CHT1; hemicholinium-3-sensitive choline transporter; high affinity choline transporter 1; solute carrier family 5 member 7
Homo sapiens (human) : SLC5A7 (solute carrier family 5 member 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Slc5a7 (solute carrier family 5 member 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc5a7 (solute carrier family 5 member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC5A7 (solute carrier family 5 member 7)
Canis lupus familiaris (dog) : SLC5A7 (solute carrier family 5 member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc5a7 (solute carrier family 5 member 7)
Sus scrofa (pig) : SLC5A7 (solute carrier family 5 member 7)
Chlorocebus sabaeus (African green monkey) : SLC5A7 (solute carrier family 5 member 7)
Heterocephalus glaber (naked mole-rat) : Slc5a7 (solute carrier family 5 member 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391754,580,618 - 54,606,071 (-)NCBI
GRCm381754,273,590 - 54,299,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1754,273,590 - 54,299,034 (-)EnsemblGRCm38mm10GRCm38
MGSCv371754,412,915 - 54,438,359 (-)NCBIGRCm37mm9NCBIm37
MGSCv361753,749,658 - 53,773,230 (-)NCBImm8
Celera1757,690,527 - 57,715,838 (-)NCBICelera
Cytogenetic Map17CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Slc5a7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736894
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.