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Gene: Hpgd (hydroxyprostaglandin dehydrogenase 15 (NAD)) Mus musculus
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Symbol: Hpgd
Name: hydroxyprostaglandin dehydrogenase 15 (NAD)
Description: Exhibits 15-hydroxyprostaglandin dehydrogenase (NAD+) activity. Involved in ductus arteriosus closure. Localizes to the basolateral plasma membrane. Human ortholog(s) of this gene implicated in colon carcinoma and primary hypertrophic osteoarthropathy. Is expressed in several structures, including alimentary system; choroid plexus; humerus cartilage condensation; nose; and urinary system. Orthologous to human HPGD (15-hydroxyprostaglandin dehydrogenase); INTERACTS WITH 1,1-dichloroethene; 15-dehydro-prostaglandin E2; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-hydroxyprostaglandin dehydrogenase [NAD+]; 15-PGDH; AV026552; MGC14001; PGDH; prostaglandin dehydrogenase 1
Orthologs:
Homo sapiens (human) : HPGD (15-hydroxyprostaglandin dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hpgd (15-hydroxyprostaglandin dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hpgd (15-hydroxyprostaglandin dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HPGD (15-hydroxyprostaglandin dehydrogenase)
Canis lupus familiaris (dog) : HPGD (15-hydroxyprostaglandin dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgd (15-hydroxyprostaglandin dehydrogenase)
Sus scrofa (pig) : HPGD (15-hydroxyprostaglandin dehydrogenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38856,294,552 - 56,321,046 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37858,773,349 - 58,799,843 (+)NCBIGRCm37mm9NCBIm37
MGSCv36859,186,738 - 59,212,816 (+)NCBImm8
Celera858,951,090 - 58,977,585 (+)NCBICelera
Cytogenetic Map8 B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hpgd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736887
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.