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Gene: Kcnq2 (potassium voltage-gated channel, subfamily Q, member 2) Mus musculus
Symbol: Kcnq2
Name: potassium voltage-gated channel, subfamily Q, member 2
Description: Exhibits calmodulin binding activity and voltage-gated ion channel activity. Involved in membrane hyperpolarization and transmission of nerve impulse. Localizes to the cell surface; main axon; and voltage-gated potassium channel complex. Used to study benign neonatal seizures. Human ortholog(s) of this gene implicated in benign neonatal seizures and early infantile epileptic encephalopathy 7. Is expressed in several structures, including brain; gut; immune system; reproductive system; and white fat. Orthologous to human KCNQ2 (potassium voltage-gated channel subfamily Q member 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HNSPC; KQT-like 2; KQT2; Nmf134; potassium channel subunit alpha KvLQT2; potassium voltage-gated channel subfamily KQT member 2; voltage-gated potassium channel subunit Kv7.2
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382181,075,579 - 181,135,580 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372180,810,284 - 180,869,930 (-)NCBIGRCm37mm9NCBIm37
MGSCv362181,004,987 - 181,064,633 (-)NCBImm8
Celera2185,162,036 - 185,221,683 (-)NCBICelera
Cytogenetic Map2 H4NCBI
cM Map2103.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kcnq2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736658
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.