Nlgn1 (neuroligin 1) - Rat Genome Database

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Gene: Nlgn1 (neuroligin 1) Mus musculus
Analyze
Symbol: Nlgn1
Name: neuroligin 1
RGD ID: 736454
MGI Page MGI
Description: Enables neurexin family protein binding activity. Involved in several processes, including positive regulation of transport; synapse organization; and synaptic vesicle cycle. Acts upstream of or within several processes, including positive regulation of synapse assembly; regulation of respiratory gaseous exchange by nervous system process; and synapse organization. Located in external side of plasma membrane and synapse. Is integral component of plasma membrane. Part of receptor complex. Is active in glutamatergic synapse. Is expressed in blood vessel and brain. Used to study autism spectrum disorder. Orthologous to human NLGN1 (neuroligin 1); INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; dextran sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330415N05Rik; BB179718; MGC107366; mKIAA1070; N; neuroligin-1; Nl; NL1; Nlg1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39325,475,972 - 26,387,504 (-)NCBIGRCm39mm39
GRCm39 Ensembl325,480,379 - 26,386,609 (-)Ensembl
GRCm38325,421,808 - 26,332,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl325,426,215 - 26,332,460 (-)EnsemblGRCm38mm10GRCm38
MGSCv37325,330,763 - 26,230,831 (-)NCBIGRCm37mm9NCBIm37
MGSCv36325,622,914 - 26,522,982 (-)NCBImm8
Celera325,414,194 - 26,317,921 (-)NCBICelera
Cytogenetic Map3A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
AMPA glutamate receptor clustering  (IDA,IMP,ISO)
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  (IDA,ISO)
cell adhesion  (IEA)
cellular response to calcium ion  (ISO)
chemical synaptic transmission  (IBA)
cytoskeletal matrix organization at active zone  (IMP,ISO)
establishment of protein localization  (IMP)
excitatory synapse assembly  (IDA,IMP)
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  (IDA)
inhibitory postsynaptic potential  (IMP)
long-term synaptic potentiation  (ISO)
modulation of chemical synaptic transmission  (IBA,IGI,ISO)
negative regulation of dendritic spine morphogenesis  (IMP,ISO)
nervous system development  (IDA,IMP,ISO)
neurexin clustering involved in presynaptic membrane assembly  (IDA)
neuron cell-cell adhesion  (IBA,IDA,ISO)
neuron projection arborization  (ISO)
neuron projection development  (ISO)
NMDA glutamate receptor clustering  (ISO)
positive regulation of circadian sleep/wake cycle, wakefulness  (IMP)
positive regulation of dendritic spine development  (IMP,ISO)
positive regulation of excitatory postsynaptic potential  (IDA,IMP,ISO)
positive regulation of filopodium assembly  (ISO)
positive regulation of intracellular signal transduction  (ISO)
positive regulation of presynaptic active zone assembly  (ISO)
positive regulation of protein localization to synapse  (ISO)
positive regulation of ruffle assembly  (ISO)
positive regulation of synapse assembly  (IDA,ISO)
positive regulation of synaptic transmission, GABAergic  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
positive regulation of synaptic vesicle clustering  (IDA)
positive regulation of synaptic vesicle endocytosis  (IMP,ISO)
positive regulation of synaptic vesicle exocytosis  (IMP,ISO)
postsynaptic density protein 95 clustering  (IDA,ISO)
postsynaptic membrane assembly  (IBA,IDA)
postsynaptic specialization assembly  (IDA,IMP)
presynaptic membrane assembly  (IBA,IDA,ISO)
protein localization to synapse  (IDA)
protein targeting  (ISO)
receptor localization to synapse  (IDA)
regulation of AMPA receptor activity  (ISO)
regulation of neuron differentiation  (IDA)
regulation of NMDA receptor activity  (IDA,IMP,ISO)
regulation of presynapse organization  (ISO)
regulation of respiratory gaseous exchange by nervous system process  (IGI)
retrograde trans-synaptic signaling by trans-synaptic protein complex  (ISO)
rhythmic process  (IEA)
synapse assembly  (IDA,ISO)
synapse organization  (IGI,ISO)
synaptic membrane adhesion  (IDA,IMP)
synaptic vesicle clustering  (IDA,ISO)
synaptic vesicle endocytosis  (IBA)
synaptic vesicle targeting  (IMP)
synaptic vesicle transport  (ISO)
terminal button organization  (IMP,ISO)

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10892652   PMID:11042159   PMID:11076861   PMID:11329178   PMID:12141453   PMID:12202822   PMID:12477932   PMID:12796785   PMID:15328020   PMID:15358863   PMID:15489334  
PMID:15620359   PMID:15681343   PMID:16141072   PMID:16141073   PMID:16186258   PMID:16602821   PMID:16794786   PMID:16919269   PMID:16982420   PMID:17360903   PMID:17582332   PMID:17897391  
PMID:18084303   PMID:18227507   PMID:18854036   PMID:19098102   PMID:19437420   PMID:19628693   PMID:19816407   PMID:19889999   PMID:19926856   PMID:19932134   PMID:20147539   PMID:20176955  
PMID:20534458   PMID:20573900   PMID:20869594   PMID:21267068   PMID:21356198   PMID:21788371   PMID:21873635   PMID:21940442   PMID:21953696   PMID:22542674   PMID:22860111   PMID:22960622  
PMID:22983708   PMID:23083741   PMID:23090496   PMID:23110172   PMID:23143522   PMID:23172145   PMID:23226954   PMID:23269831   PMID:23358245   PMID:23559421   PMID:23716671   PMID:23719805  
PMID:23791195   PMID:24083347   PMID:24336150   PMID:24441681   PMID:24448406   PMID:24613359   PMID:24860089   PMID:25149987   PMID:25592157   PMID:25595979   PMID:25713840   PMID:25839034  
PMID:26078884   PMID:26209464   PMID:26291161   PMID:26403076   PMID:26440732   PMID:26678009   PMID:26771491   PMID:26880202   PMID:26979420   PMID:27473321   PMID:27581450   PMID:27779093  
PMID:28283575   PMID:28297673   PMID:28607166   PMID:28706196   PMID:28841651   PMID:28864826   PMID:28939043   PMID:29100073   PMID:29278843   PMID:29724786   PMID:29742426   PMID:30046996  
PMID:30049666   PMID:30056576   PMID:30201312   PMID:30266599   PMID:30266896   PMID:30871858   PMID:31138690   PMID:31665629   PMID:32324534   PMID:32332783   PMID:32719346   PMID:32915137  
PMID:32921313  


Genomics

Comparative Map Data
Nlgn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39325,475,972 - 26,387,504 (-)NCBIGRCm39mm39
GRCm39 Ensembl325,480,379 - 26,386,609 (-)Ensembl
GRCm38325,421,808 - 26,332,866 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl325,426,215 - 26,332,460 (-)EnsemblGRCm38mm10GRCm38
MGSCv37325,330,763 - 26,230,831 (-)NCBIGRCm37mm9NCBIm37
MGSCv36325,622,914 - 26,522,982 (-)NCBImm8
Celera325,414,194 - 26,317,921 (-)NCBICelera
Cytogenetic Map3A3NCBI
NLGN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3173,396,284 - 174,286,644 (+)EnsemblGRCh38hg38GRCh38
GRCh383173,395,929 - 174,294,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373173,113,742 - 174,012,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363174,598,938 - 175,483,810 (+)NCBINCBI36hg18NCBI36
Build 343174,598,945 - 175,483,818NCBI
Celera3171,515,223 - 172,400,529 (+)NCBI
Cytogenetic Map3q26.31NCBI
HuRef3170,489,300 - 171,374,847 (+)NCBIHuRef
CHM1_13173,079,120 - 173,964,074 (+)NCBICHM1_1
Nlgn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22108,256,236 - 109,181,530 (-)NCBI
Rnor_6.0 Ensembl2111,057,291 - 111,793,326 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02111,057,291 - 111,973,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02130,770,580 - 131,688,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42111,189,470 - 111,948,145 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12111,133,661 - 111,893,471 (-)NCBI
Celera2103,515,760 - 104,229,754 (-)NCBICelera
Cytogenetic Map2q24NCBI
Nlgn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554203,549,021 - 4,167,493 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554203,360,745 - 4,171,587 (+)NCBIChiLan1.0ChiLan1.0
NLGN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13178,595,014 - 179,505,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3178,810,253 - 179,503,756 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03170,416,885 - 171,333,094 (+)NCBIMhudiblu_PPA_v0panPan3
NLGN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13437,397,772 - 38,203,634 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3437,572,629 - 38,203,177 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3446,409,660 - 47,225,945 (+)NCBI
ROS_Cfam_1.03437,484,369 - 38,313,800 (+)NCBI
UMICH_Zoey_3.13437,576,956 - 38,230,342 (+)NCBI
UNSW_CanFamBas_1.03437,390,518 - 38,201,245 (+)NCBI
UU_Cfam_GSD_1.03437,647,698 - 38,463,980 (+)NCBI
Nlgn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602104,390,734 - 105,051,988 (+)NCBI
SpeTri2.0NW_004936703951,935 - 1,415,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLGN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13112,036,053 - 112,725,618 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113111,851,007 - 112,727,202 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213120,802,484 - 121,025,494 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NLGN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11515,129,976 - 16,017,107 (-)NCBI
Vero_WHO_p1.0NW_02366606323,867,631 - 24,767,924 (-)NCBI
Nlgn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473051,451,546 - 52,300,413 (+)NCBI

Position Markers
BB392043  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38325,433,312 - 25,433,434UniSTSGRCm38
MGSCv37325,332,234 - 25,332,356UniSTSGRCm37
Celera325,415,665 - 25,415,787UniSTS
Cytogenetic Map3A3UniSTS
Whitehead/MRC_RH3293.86UniSTS
BB391041  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38325,432,368 - 25,432,462UniSTSGRCm38
MGSCv37325,331,290 - 25,331,384UniSTSGRCm37
Celera325,414,721 - 25,414,815UniSTS
Cytogenetic Map3A3UniSTS
Whitehead/MRC_RH3295.99UniSTS
RH127137  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38325,668,920 - 25,669,138UniSTSGRCm38
MGSCv37325,567,842 - 25,568,060UniSTSGRCm37
Celera325,645,066 - 25,645,284UniSTS
Cytogenetic Map3A3UniSTS
Whitehead/MRC_RH3297.67UniSTS
BB179718  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38326,332,139 - 26,332,279UniSTSGRCm38
MGSCv37326,231,061 - 26,231,201UniSTSGRCm37
Celera326,318,151 - 26,318,291UniSTS
Cytogenetic Map3A3UniSTS
Whitehead/MRC_RH3303.7UniSTS
12.MMHAP85FRD9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38326,029,390 - 26,029,508UniSTSGRCm38
MGSCv37325,928,312 - 25,928,430UniSTSGRCm37
Celera326,012,267 - 26,012,385UniSTS
Cytogenetic Map3A3UniSTS
Whitehead_YAC3 UniSTS
15.MMHAP14FLE3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38325,873,602 - 25,873,751UniSTSGRCm38
MGSCv37325,772,524 - 25,772,673UniSTSGRCm37
Celera325,849,845 - 25,849,994UniSTS
Cytogenetic Map3A3UniSTS
Whitehead_YAC3 UniSTS
21.MMHAP50FRG9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38326,088,309 - 26,088,390UniSTSGRCm38
MGSCv37325,987,231 - 25,987,312UniSTSGRCm37
Celera326,071,749 - 26,071,830UniSTS
Celera326,071,163 - 26,071,830UniSTS
Cytogenetic Map3A3UniSTS
Whitehead_YAC3 UniSTS
D3Mit92  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38326,182,244 - 26,182,486UniSTSGRCm38
MGSCv37326,081,166 - 26,081,408UniSTSGRCm37
Celera326,168,761 - 26,168,997UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.6UniSTS
Whitehead Genetic38.7UniSTS
D3Mit92.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38326,182,184 - 26,182,299UniSTSGRCm38
MGSCv37326,081,106 - 26,081,221UniSTSGRCm37
Celera326,168,701 - 26,168,816UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.6UniSTS
cM Map3 UniSTS
Whitehead_YAC3 UniSTS
UniSTS:224698  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38325,511,553 - 25,511,741UniSTSGRCm38
MGSCv37325,410,475 - 25,410,663UniSTSGRCm37
Celera325,493,485 - 25,493,673UniSTS
Cytogenetic Map3A3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301256Skmw1_mskeletal muscle weight 1 (mouse)Not determined3125721372Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3447125538471355Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31157630445576442Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1823401952234019Mouse
25671383Hrsq1_mhost response to SARS QTL 1, vascular cuffing (mouse)31838679026769492Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32012071354125954Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32471406831277954Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1291
Count of miRNA genes:333
Interacting mature miRNAs:424
Transcripts:ENSMUST00000075054, ENSMUST00000108308
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001357097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_138666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006535425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC100381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC107806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC108852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LXEJ02003451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000075054   ⟹   ENSMUSP00000074565
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl325,431,811 - 26,133,734 (-)Ensembl
RefSeq Acc Id: ENSMUST00000108308   ⟹   ENSMUSP00000103944
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl325,431,811 - 26,133,734 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191835   ⟹   ENSMUSP00000142086
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl325,433,431 - 26,153,307 (-)Ensembl
RefSeq Acc Id: ENSMUST00000192774
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl326,131,670 - 26,331,870 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193603   ⟹   ENSMUSP00000142200
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl325,426,215 - 26,332,460 (-)Ensembl
RefSeq Acc Id: NM_001163387   ⟹   NP_001156859
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,135 (-)NCBI
GRCm38325,421,808 - 26,153,986 (-)NCBI
MGSCv37325,330,763 - 26,230,831 (-)RGD
Celera325,414,194 - 26,317,921 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001357095   ⟹   NP_001344024
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,135 (-)NCBI
GRCm38325,421,808 - 26,153,986 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357096   ⟹   NP_001344025
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,135 (-)NCBI
GRCm38325,421,808 - 26,153,986 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357097   ⟹   NP_001344026
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,135 (-)NCBI
GRCm38325,421,808 - 26,153,986 (-)NCBI
Sequence:
RefSeq Acc Id: NM_138666   ⟹   NP_619607
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,386,058 (-)NCBI
GRCm38325,421,808 - 26,331,909 (-)NCBI
MGSCv37325,330,763 - 26,230,831 (-)RGD
Celera325,414,194 - 26,317,921 (-)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006535415   ⟹   XP_006535478
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,722 (-)NCBI
GRCm38325,421,808 - 26,154,573 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535416   ⟹   XP_006535479
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,196,783 (-)NCBI
GRCm38325,421,808 - 26,142,634 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535418   ⟹   XP_006535481
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535419   ⟹   XP_006535482
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,189,624 (-)NCBI
GRCm38325,421,808 - 26,135,475 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535420   ⟹   XP_006535483
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,208,133 (-)NCBI
GRCm38325,421,808 - 26,154,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535421   ⟹   XP_006535484
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535422   ⟹   XP_006535485
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535423   ⟹   XP_006535486
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535424   ⟹   XP_006535487
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006535425   ⟹   XP_006535488
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
GRCm38325,421,808 - 26,332,866 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030252466   ⟹   XP_030108326
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,504 (-)NCBI
GRCm38325,421,808 - 26,331,076 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162946   ⟹   XP_036018839
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,722 (-)NCBI
RefSeq Acc Id: XM_036162947   ⟹   XP_036018840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,208,722 (-)NCBI
RefSeq Acc Id: XM_036162948   ⟹   XP_036018841
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
RefSeq Acc Id: XM_036162949   ⟹   XP_036018842
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,208,133 (-)NCBI
RefSeq Acc Id: XM_036162950   ⟹   XP_036018843
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,189,538 (-)NCBI
RefSeq Acc Id: XM_036162951   ⟹   XP_036018844
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
RefSeq Acc Id: XM_036162952   ⟹   XP_036018845
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
RefSeq Acc Id: XM_036162953   ⟹   XP_036018846
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
RefSeq Acc Id: XM_036162954   ⟹   XP_036018847
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,977 - 26,387,015 (-)NCBI
RefSeq Acc Id: XM_036162955   ⟹   XP_036018848
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39325,475,972 - 26,188,201 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001156859 (Get FASTA)   NCBI Sequence Viewer  
  NP_001344024 (Get FASTA)   NCBI Sequence Viewer  
  NP_001344025 (Get FASTA)   NCBI Sequence Viewer  
  NP_001344026 (Get FASTA)   NCBI Sequence Viewer  
  NP_619607 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535478 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535479 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535481 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535482 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535483 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535484 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535485 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535486 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535487 (Get FASTA)   NCBI Sequence Viewer  
  XP_006535488 (Get FASTA)   NCBI Sequence Viewer  
  XP_030108326 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018839 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018840 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018841 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018842 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018843 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018844 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018845 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018846 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018847 (Get FASTA)   NCBI Sequence Viewer  
  XP_036018848 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH05523 (Get FASTA)   NCBI Sequence Viewer  
  AAH98461 (Get FASTA)   NCBI Sequence Viewer  
  BAC65715 (Get FASTA)   NCBI Sequence Viewer  
  BAE23583 (Get FASTA)   NCBI Sequence Viewer  
  BAE34679 (Get FASTA)   NCBI Sequence Viewer  
  BAE36885 (Get FASTA)   NCBI Sequence Viewer  
  Q99K10 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_619607   ⟸   NM_138666
- Peptide Label: isoform 1 precursor
- UniProtKB: Q99K10 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001156859   ⟸   NM_001163387
- Peptide Label: isoform 2
- UniProtKB: E9QK34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006535488   ⟸   XM_006535425
- Peptide Label: isoform X7
- UniProtKB: E9QK34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006535487   ⟸   XM_006535424
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006535486   ⟸   XM_006535423
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006535485   ⟸   XM_006535422
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006535484   ⟸   XM_006535421
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006535481   ⟸   XM_006535418
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006535478   ⟸   XM_006535415
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006535483   ⟸   XM_006535420
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006535479   ⟸   XM_006535416
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006535482   ⟸   XM_006535419
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030108326   ⟸   XM_030252466
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001344026   ⟸   NM_001357097
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001344025   ⟸   NM_001357096
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001344024   ⟸   NM_001357095
- Peptide Label: isoform 3
RefSeq Acc Id: ENSMUSP00000103944   ⟸   ENSMUST00000108308
RefSeq Acc Id: ENSMUSP00000142086   ⟸   ENSMUST00000191835
RefSeq Acc Id: ENSMUSP00000142200   ⟸   ENSMUST00000193603
RefSeq Acc Id: ENSMUSP00000074565   ⟸   ENSMUST00000075054
RefSeq Acc Id: XP_036018840   ⟸   XM_036162947
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036018839   ⟸   XM_036162946
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036018843   ⟸   XM_036162950
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036018848   ⟸   XM_036162955
- Peptide Label: isoform X9
RefSeq Acc Id: XP_036018846   ⟸   XM_036162953
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036018844   ⟸   XM_036162951
- Peptide Label: isoform X6
RefSeq Acc Id: XP_036018841   ⟸   XM_036162948
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036018847   ⟸   XM_036162954
- Peptide Label: isoform X8
RefSeq Acc Id: XP_036018845   ⟸   XM_036162952
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036018842   ⟸   XM_036162949
- Peptide Label: isoform X3
Protein Domains
COesterase

Promoters
RGD ID:6834156
Promoter ID:MM_KWN:33900
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000075054,   ENSMUST00000108308
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36326,032,426 - 26,032,926 (-)MPROMDB
RGD ID:6834158
Promoter ID:MM_KWN:33901
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_001163387
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36326,051,601 - 26,052,101 (-)MPROMDB
RGD ID:6880344
Promoter ID:EPDNEW_M3623
Type:single initiation site
Name:Nlgn1_2
Description:Mus musculus neuroligin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3624  EPDNEW_M3625  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38326,153,252 - 26,153,312EPDNEW
RGD ID:6880346
Promoter ID:EPDNEW_M3624
Type:single initiation site
Name:Nlgn1_3
Description:Mus musculus neuroligin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3623  EPDNEW_M3625  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38326,153,897 - 26,153,957EPDNEW
RGD ID:6834179
Promoter ID:MM_KWN:33902
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_138666,   UC008OTD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36326,230,326 - 26,230,826 (-)MPROMDB
RGD ID:6880348
Promoter ID:EPDNEW_M3625
Type:multiple initiation site
Name:Nlgn1_1
Description:Mus musculus neuroligin 1 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3623  EPDNEW_M3624  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38326,331,867 - 26,331,927EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2179435 AgrOrtholog
Ensembl Genes ENSMUSG00000063887 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000074565 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000103944 UniProtKB/TrEMBL
  ENSMUSP00000142086 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000142200 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000075054 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000108308 UniProtKB/TrEMBL
  ENSMUST00000191835 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000193603 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CarbesteraseB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carboxylesterase_B_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nlgn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLGN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:192167 UniProtKB/Swiss-Prot
MGD MGI:2179435 ENTREZGENE
NCBI Gene 192167 ENTREZGENE
PANTHER PTHR43903:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COesterase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nlgn1 PhenoGen
PRINTS NEUROLIGIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CARBOXYLESTERASE_B_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9QK34 ENTREZGENE, UniProtKB/TrEMBL
  NLGN1_MOUSE UniProtKB/Swiss-Prot
  Q3TRZ1_MOUSE UniProtKB/TrEMBL
  Q3TY84_MOUSE UniProtKB/TrEMBL
  Q3UUP2_MOUSE UniProtKB/TrEMBL
  Q4KMN5_MOUSE UniProtKB/TrEMBL
  Q99K10 ENTREZGENE