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Gene: CALM2 (calmodulin 2) Homo sapiens
Symbol: CALM2
Name: calmodulin 2
Description: Exhibits several functions, including N-terminal myristoylation domain binding activity; enzyme binding activity; and molecular function regulator. Involved in several processes, including positive regulation of hydrolase activity; regulation of heart contraction; and regulation of release of sequestered calcium ion into cytosol. Localizes to several cellular components, including calcium channel complex; microtubule cytoskeleton; and sarcomere. Implicated in long QT syndrome 15. Biomarker of major depressive disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CALM; CALM1; CALM3; CALML2; calmodulin; calmodulin 2 (phosphorylase kinase, delta); Calmodulin-1; calmodulin-2; Calmodulin-3; caM; CAM1; CAM3; CAMC; CAMII; CAMIII; FLJ99410; LP7057 protein; LQT15; PHKD; PHKD2; phosphorylase kinase delta; phosphorylase kinase subunit delta; prepro-calmodulin 2
Mus musculus (house mouse) : Calm2 (calmodulin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Calm2 (calmodulin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Calm2 (calmodulin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CALM2 (calmodulin 2)
Canis lupus familiaris (dog) : CALM2 (calmodulin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Calm2 (calmodulin 2)
Sus scrofa (pig) : CALM2 (calmodulin 2)
Chlorocebus sabaeus (African green monkey) : CALM2 (calmodulin 2)
Heterocephalus glaber (naked mole-rat) : Calm2 (calmodulin 2)
more info ...
Related Pseudogenes: CALM2P1   CALM2P2   CALM2P3   CALM2P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl247,160,083 - 47,176,921 (-)EnsemblGRCh38hg38GRCh38
GRCh38247,160,082 - 47,176,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37247,387,221 - 47,404,229 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36247,240,809 - 47,257,154 (-)NCBINCBI36hg18NCBI36
Build 34247,298,955 - 47,315,301NCBI
Celera247,226,054 - 47,242,551 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef247,124,359 - 47,140,853 (-)NCBIHuRef
CHM1_1247,317,465 - 47,334,257 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CALM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736342
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-04-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.