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Gene: Robo2 (roundabout guidance receptor 2) Mus musculus
Symbol: Robo2
Name: roundabout guidance receptor 2
Description: Predicted to have axon guidance receptor activity and identical protein binding activity. Involved in several processes, including circulatory system development; kidney development; and neuron development. Localizes to axolemma. Is expressed in several structures, including embryo mesenchyme; foot; nervous system; tooth; and urinary system. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human ROBO2 (roundabout guidance receptor 2); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2600013A04Rik; 9430089E08Rik; BB097918; D230004I22Rik; expressed sequence BB097918; mKIAA1568; roundabout homolog 2
Homo sapiens (human) : ROBO2 (roundabout guidance receptor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Robo2 (roundabout guidance receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Robo2 (roundabout guidance receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ROBO2 (roundabout guidance receptor 2)
Canis lupus familiaris (dog) : ROBO2 (roundabout guidance receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Robo2 (roundabout guidance receptor 2)
Sus scrofa (pig) : ROBO2 (roundabout guidance receptor 2)
Chlorocebus sabaeus (African green monkey) : ROBO2 (roundabout guidance receptor 2)
Heterocephalus glaber (naked mole-rat) : Robo2 (roundabout guidance receptor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1673,891,839 - 74,411,825 (-)EnsemblGRCm38mm10GRCm38
GRCm381673,891,976 - 75,447,443 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371673,892,551 - 74,411,157 (-)NCBIGRCm37mm9NCBIm37
MGSCv361673,802,886 - 74,293,900 (-)NCBImm8
Celera1674,137,198 - 74,644,299 (-)NCBICelera
Cytogenetic Map16C3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Robo2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736257
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.