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Gene: Otx1 (orthodenticle homeobox 1) Mus musculus
Symbol: Otx1
Name: orthodenticle homeobox 1
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including anterior/posterior pattern specification; brain development; and inner ear morphogenesis. Predicted to localize to the nucleus. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; nervous system; and sensory organ. Orthologous to human OTX1 (orthodenticle homeobox 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A730044F23Rik; homeobox protein OTX1; jv; orthodenticle homolog 1
Homo sapiens (human) : OTX1 (orthodenticle homeobox 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Otx1 (orthodenticle homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otx1 (orthodenticle homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OTX1 (orthodenticle homeobox 1)
Canis lupus familiaris (dog) : OTX1 (orthodenticle homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otx1 (orthodenticle homeobox 1)
Sus scrofa (pig) : OTX1 (orthodenticle homeobox 1)
Chlorocebus sabaeus (green monkey) : OTX1 (orthodenticle homeobox 1)
Heterocephalus glaber (naked mole-rat) : Otx1 (orthodenticle homeobox 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1121,994,764 - 22,002,897 (-)Ensembl
GRCm381121,994,764 - 22,001,651 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371121,894,767 - 21,901,654 (-)NCBIGRCm37mm9NCBIm37
MGSCv361121,894,767 - 21,901,654 (-)NCBImm8
Celera1124,135,716 - 24,142,604 (-)NCBICelera
Cytogenetic Map11 A3.2NCBI
cM Map1114.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Otx1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736237
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.