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Gene: Scn10a (sodium channel, voltage-gated, type X, alpha) Mus musculus
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Symbol: Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; ion channel binding (ortholog); INVOLVED IN cardiac conduction; regulation of atrial cardiac muscle cell membrane depolarization; sodium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal action potential; abnormal behavioral response to addictive substance; abnormal brain wave pattern; ASSOCIATED WITH atrial fibrillation (ortholog); Brugada syndrome (ortholog); Episodic Pain Syndrome, Familial, 2 (ortholog); FOUND IN axon; C-fiber; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; SNS; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; voltage gated sodium channel; voltage-gated sodium channel Nav1.8 variant a; voltage-gated sodium channel Nav1.8 variant b; voltage-gated sodium channel subunit alpha Nav1.8
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389119,608,456 - 119,719,322 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,517,584 - 119,603,478 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,457,165 - 119,543,058 (-)NCBImm8
Celera9120,082,157 - 120,189,198 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Scn10a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736179
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.