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Gene: Scn10a (sodium channel, voltage-gated, type X, alpha) Mus musculus
Symbol: Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; ion channel binding (ortholog); INVOLVED IN cardiac conduction; regulation of atrial cardiac muscle cell membrane depolarization; sodium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal action potential; abnormal behavioral response to addictive substance; abnormal brain wave pattern; ASSOCIATED WITH atrial fibrillation (ortholog); Brugada syndrome (ortholog); Episodic Pain Syndrome, Familial, 2 (ortholog); FOUND IN axon; C-fiber; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; SNS; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; voltage gated sodium channel; voltage-gated sodium channel Nav1.8 variant a; voltage-gated sodium channel Nav1.8 variant b; voltage-gated sodium channel subunit alpha Nav1.8
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389119,608,456 - 119,719,322 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,517,584 - 119,603,478 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,457,165 - 119,543,058 (-)NCBImm8
Celera9120,082,157 - 120,189,198 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Scn10a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736179
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.