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Gene: ARHGEF7 (Rho guanine nucleotide exchange factor 7) Homo sapiens
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Symbol: ARHGEF7
Name: Rho guanine nucleotide exchange factor 7
Description: Exhibits guanyl-nucleotide exchange factor activity and protein kinase binding activity. Involved in several processes, including Golgi organization; positive regulation of GTPase activity; and regulation of GTP binding activity. Localizes to neuron projection; neuronal cell body; and protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BETA-PIX; COOL-1; COOL1; DKFZp686C12170; DKFZp761K1021; guanine nucleotide exchange factor 7; KIAA0142; KIAA0412; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK-interacting exchange factor beta; PAK3; PIXB; Rho guanine nucleotide exchange factor (GEF) 7; SH3 domain-containing proline-rich protein
Orthologs:
Mus musculus (house mouse) : Arhgef7 (Rho guanine nucleotide exchange factor (GEF7))  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgef7 (Rho guanine nucleotide exchange factor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef7 (Rho guanine nucleotide exchange factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Canis lupus familiaris (dog) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef7 (Rho guanine nucleotide exchange factor 7)
Sus scrofa (pig) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Chlorocebus sabaeus (African green monkey) : ARHGEF7 (Rho guanine nucleotide exchange factor 7)
Heterocephalus glaber (naked mole-rat) : Arhgef7 (Rho guanine nucleotide exchange factor 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl13111,114,559 - 111,305,737 (+)EnsemblGRCh38hg38GRCh38
GRCh3813111,114,619 - 111,305,734 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713111,767,624 - 111,958,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613110,565,783 - 110,756,079 (+)NCBINCBI36hg18NCBI36
Build 3413110,565,782 - 110,745,543NCBI
Celera1392,614,729 - 92,805,032 (+)NCBI
Cytogenetic Map13q34NCBI
HuRef1392,335,232 - 92,556,608 (+)NCBIHuRef
CHM1_113111,734,907 - 111,925,520 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARHGEF7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736143
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.