DRD4 (dopamine receptor D4) - Rat Genome Database

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Gene: DRD4 (dopamine receptor D4) Homo sapiens
Analyze
Symbol: DRD4
Name: dopamine receptor D4
RGD ID: 736138
HGNC Page HGNC
Description: Enables several functions, including SH3 domain binding activity; catecholamine binding activity; and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including adenylate cyclase-inhibiting dopamine receptor signaling pathway; arachidonic acid secretion; and regulation of ion transmembrane transporter activity. Located in plasma membrane. Is integral component of plasma membrane. Implicated in several diseases, including Gilles de la Tourette syndrome; antisocial personality disorder; attention deficit hyperactivity disorder; conduct disorder; and dyslexia. Biomarker of Alzheimer's disease; attention deficit hyperactivity disorder; pervasive developmental disorder; and schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; dopamine D4 receptor; dopamine receptor 4; seven transmembrane helix receptor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11637,269 - 640,706 (+)EnsemblGRCh38hg38GRCh38
GRCh3811637,269 - 640,706 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711637,269 - 640,706 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611627,305 - 630,703 (+)NCBINCBI36hg18NCBI36
Build 3411627,304 - 630,703NCBI
Celera11702,422 - 705,821 (+)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11452,513 - 456,039 (+)NCBIHuRef
CHM1_111636,234 - 639,634 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-butaclamol  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3,7-dihydropurine-6-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acrylamide  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP)
clozapine  (EXP,ISO)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dieldrin  (ISO)
Dimethylphosphate  (EXP)
dopamine  (EXP,ISO)
dorsomorphin  (EXP)
fenvalerate  (ISO)
flavonoids  (ISO)
folic acid  (ISO)
fucoxanthin  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
haloperidol  (EXP,ISO)
hydralazine  (EXP)
ketoconazole  (ISO)
L-methionine  (ISO)
maneb  (ISO)
mercaptopurine  (ISO)
mercury atom  (ISO)
mercury dibromide  (EXP)
mercury(0)  (ISO)
methamphetamine  (EXP,ISO)
methylmercury chloride  (EXP)
methylphenidate  (EXP)
morphine  (ISO)
N-(1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide  (EXP)
naloxone  (ISO)
oxidopamine  (ISO)
paraquat  (ISO)
phenylmercury acetate  (EXP)
picrotoxin  (ISO)
progesterone  (ISO)
purine-6-thiol  (ISO)
pyridaben  (ISO)
quercetin  (ISO)
quinpirole  (ISO)
ropinirole  (EXP)
SB 431542  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium chloride  (ISO)
spiperone  (EXP,ISO)
temozolomide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-inhibiting dopamine receptor signaling pathway  (IDA,IMP,ISO)
adult locomotory behavior  (ISO,ISS)
arachidonic acid secretion  (IDA)
associative learning  (ISO)
behavioral fear response  (ISO,NAS)
behavioral response to cocaine  (ISO,ISS)
behavioral response to ethanol  (TAS)
cellular calcium ion homeostasis  (IC)
chemical synaptic transmission  (IBA)
circadian rhythm  (ISO)
dopamine metabolic process  (IC)
dopamine receptor signaling pathway  (IDA,ISO)
fear response  (ISO,ISS)
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  (IBA)
G protein-coupled serotonin receptor signaling pathway  (IEA)
inhibitory postsynaptic potential  (ISO,ISS)
negative regulation of protein secretion  (IDA)
negative regulation of synaptic transmission  (ISO)
negative regulation of vascular associated smooth muscle cell migration  (ISO)
negative regulation of vascular associated smooth muscle cell proliferation  (ISO)
negative regulation of voltage-gated calcium channel activity  (IDA)
olfactory learning  (ISO)
photoperiodism  (ISO)
positive regulation of dopamine uptake involved in synaptic transmission  (IC)
positive regulation of excitatory postsynaptic potential  (ISO)
positive regulation of kinase activity  (IDA)
positive regulation of MAP kinase activity  (IDA)
positive regulation of penile erection  (ISO)
positive regulation of sodium:proton antiporter activity  (IDA)
regulation of calcium-mediated signaling  (ISO)
regulation of circadian rhythm  (ISS)
regulation of dopamine metabolic process  (ISO,ISS)
regulation of neurotransmitter secretion  (ISO)
regulation of postsynaptic membrane neurotransmitter receptor levels  (ISO)
regulation of postsynaptic neurotransmitter receptor internalization  (IEA)
regulation of synaptic vesicle exocytosis  (ISO)
response to amphetamine  (ISO,ISS)
response to histamine  (IDA)
response to steroid hormone  (ISO)
retina development in camera-type eye  (ISO)
rhythmic process  (IEA)
short-term memory  (ISO)
social behavior  (NAS)
synaptic transmission, dopaminergic  (IEA,ISO)

References

References - curated
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Additional References at PubMed
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PMID:25660313   PMID:25679126   PMID:25687785   PMID:25736807   PMID:25804664   PMID:25840828   PMID:25854875   PMID:25869327   PMID:25956290   PMID:26006708   PMID:26037358   PMID:26189764  
PMID:26246555   PMID:26307064   PMID:26350252   PMID:26424426   PMID:26427473   PMID:26439067   PMID:26449981   PMID:26595468   PMID:26595480   PMID:26597879   PMID:26601911   PMID:26613685  
PMID:26665568   PMID:26680992   PMID:26688118   PMID:26717573   PMID:26782007   PMID:26897359   PMID:26902782   PMID:26950642   PMID:26990357   PMID:27045841   PMID:27077527   PMID:27155323  
PMID:27170266   PMID:27195896   PMID:27267123   PMID:27268567   PMID:27475724   PMID:27485706   PMID:27494520   PMID:27548745   PMID:27581946   PMID:27659709   PMID:27726127   PMID:27753212  
PMID:27786532   PMID:27815333   PMID:27821512   PMID:27905471   PMID:27992450   PMID:28097219   PMID:28103253   PMID:28138806   PMID:28176268   PMID:28234207   PMID:28258362   PMID:28282463  
PMID:28361337   PMID:28450726   PMID:28727140   PMID:28797200   PMID:28846959   PMID:28876518   PMID:28948080   PMID:29051383   PMID:29054088   PMID:29145734   PMID:29149620   PMID:29182037  
PMID:29221470   PMID:29294665   PMID:29395188   PMID:29455021   PMID:29564731   PMID:30009502   PMID:30035571   PMID:30099719   PMID:30248905   PMID:30260901   PMID:30364935   PMID:30367264  
PMID:30387076   PMID:30411855   PMID:30991630   PMID:31003069   PMID:31149768   PMID:31291235   PMID:31378722   PMID:31447121   PMID:31719518   PMID:31809838   PMID:31927071   PMID:32032490  
PMID:32075956   PMID:32183536   PMID:32589693   PMID:32751662   PMID:32814053   PMID:33530977   PMID:33544778  


Genomics

Comparative Map Data
DRD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11637,269 - 640,706 (+)EnsemblGRCh38hg38GRCh38
GRCh3811637,269 - 640,706 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711637,269 - 640,706 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611627,305 - 630,703 (+)NCBINCBI36hg18NCBI36
Build 3411627,304 - 630,703NCBI
Celera11702,422 - 705,821 (+)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11452,513 - 456,039 (+)NCBIHuRef
CHM1_111636,234 - 639,634 (+)NCBICHM1_1
Drd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,871,887 - 140,876,377 (+)NCBIGRCm39mm39
GRCm39 Ensembl7140,871,919 - 140,876,377 (+)Ensembl
GRCm387141,291,974 - 141,296,464 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,292,006 - 141,296,464 (+)EnsemblGRCm38mm10GRCm38
MGSCv377148,477,905 - 148,480,900 (+)NCBIGRCm37mm9NCBIm37
MGSCv367141,143,326 - 141,146,321 (+)NCBImm8
Celera7141,085,754 - 141,088,749 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.6NCBI
Drd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21196,396,366 - 196,400,824 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1196,396,366 - 196,399,553 (+)Ensembl
Rnor_6.01214,278,296 - 214,282,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,278,296 - 214,281,483 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,195,844 - 221,200,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,485,597 - 201,488,784 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,636,931 - 201,640,119 (+)NCBI
Celera1194,030,237 - 194,033,424 (+)NCBICelera
RH 3.4 Map11437.21RGD
Cytogenetic Map1q41NCBI
Drd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,424,411 - 11,426,960 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,424,347 - 11,426,962 (-)NCBIChiLan1.0ChiLan1.0
DRD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111671,445 - 674,412 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v011640,401 - 646,775 (+)NCBIMhudiblu_PPA_v0panPan3
DRD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1825,378,476 - 25,381,179 (+)NCBI
ROS_Cfam_1.01826,314,100 - 26,316,803 (+)NCBI
UMICH_Zoey_3.11825,823,586 - 25,826,358 (+)NCBI
UNSW_CanFamBas_1.01825,468,566 - 25,471,386 (+)NCBI
UU_Cfam_GSD_1.01826,081,003 - 26,083,706 (+)NCBI
Drd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947468,387 - 471,254 (+)NCBI
SpeTri2.0NW_004936888468,334 - 471,254 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2398,766 - 401,432 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12398,766 - 401,539 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22272,619 - 275,757 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11454,018 - 459,582 (+)NCBI
Vero_WHO_p1.0NW_02366603897,516,746 - 97,520,656 (+)NCBI
Drd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476621,834,093 - 21,837,314 (-)NCBI

Position Markers
RH71428  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711640,546 - 640,685UniSTSGRCh37
Build 3611630,546 - 630,685RGDNCBI36
Celera11705,661 - 705,800RGD
Cytogenetic Map11p15.5UniSTS
HuRef11455,879 - 456,018UniSTS
GeneMap99-GB4 RH Map1118.88UniSTS
RH27290  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711640,312 - 640,727UniSTSGRCh37
Build 3611630,312 - 630,727RGDNCBI36
Celera11705,427 - 705,842RGD
Cytogenetic Map11p15.5UniSTS
HuRef11455,645 - 456,060UniSTS
GDB:196985  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711639,917 - 640,234UniSTSGRCh37
Build 3611629,917 - 630,234RGDNCBI36
Celera11705,032 - 705,349RGD
Cytogenetic Map11p15.5UniSTS
HuRef11455,250 - 455,567UniSTS
GDB:311107  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711636,883 - 637,591UniSTSGRCh37
Build 3611626,883 - 627,591RGDNCBI36
Celera11702,000 - 702,708RGD
Cytogenetic Map11p15.5UniSTS
HuRef11452,091 - 452,799UniSTS
GDB:374242  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711639,274 - 639,417UniSTSGRCh37
Build 3611629,274 - 629,417RGDNCBI36
Celera11704,389 - 704,532RGD
Cytogenetic Map11p15.5UniSTS
HuRef11454,480 - 454,623UniSTS
PMC117557P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711639,756 - 640,460UniSTSGRCh37
Build 3611629,756 - 630,460RGDNCBI36
Celera11704,871 - 705,575RGD
Cytogenetic Map11p15.5UniSTS
HuRef11455,089 - 455,793UniSTS
PMC130047P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711639,818 - 640,292UniSTSGRCh37
Build 3611629,818 - 630,292RGDNCBI36
Celera11704,933 - 705,407RGD
Cytogenetic Map11p15.5UniSTS
HuRef11455,151 - 455,625UniSTS
PMC130047P2  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11p15.5UniSTS
HuRef11451,887 - 452,170UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:677
Count of miRNA genes:536
Interacting mature miRNAs:600
Transcripts:ENST00000176183, ENST00000528733
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 37 17 94 5 15 5 75 25 162 3 157 30 1 1 10 20
Low 2297 1837 1464 476 892 352 3912 1566 3505 307 1257 1494 137 1124 2462 3
Below cutoff 97 1104 163 137 797 103 360 596 57 97 35 83 35 70 304 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_021241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB065765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB107017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB107018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB107019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF395264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP006284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY151038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM674709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU432112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ064953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L12397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L12398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S76942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S82917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S82918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000176183   ⟹   ENSP00000176183
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl11637,269 - 640,706 (+)Ensembl
RefSeq Acc Id: ENST00000528733
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl11639,057 - 639,793 (+)Ensembl
RefSeq Acc Id: NM_000797   ⟹   NP_000788
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811637,269 - 640,706 (+)NCBI
GRCh3711637,305 - 640,706 (+)ENTREZGENE
Build 3611627,305 - 630,703 (+)NCBI Archive
HuRef11452,513 - 456,039 (+)ENTREZGENE
CHM1_111636,234 - 639,634 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000788 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB33728 (Get FASTA)   NCBI Sequence Viewer  
  AAB46802 (Get FASTA)   NCBI Sequence Viewer  
  AAB46803 (Get FASTA)   NCBI Sequence Viewer  
  AAB59386 (Get FASTA)   NCBI Sequence Viewer  
  AAL35159 (Get FASTA)   NCBI Sequence Viewer  
  AAL35160 (Get FASTA)   NCBI Sequence Viewer  
  AAL35161 (Get FASTA)   NCBI Sequence Viewer  
  AAL35162 (Get FASTA)   NCBI Sequence Viewer  
  AAL35163 (Get FASTA)   NCBI Sequence Viewer  
  AAL35164 (Get FASTA)   NCBI Sequence Viewer  
  AAL35165 (Get FASTA)   NCBI Sequence Viewer  
  AAL35166 (Get FASTA)   NCBI Sequence Viewer  
  AAL35167 (Get FASTA)   NCBI Sequence Viewer  
  AAL35168 (Get FASTA)   NCBI Sequence Viewer  
  AAL35169 (Get FASTA)   NCBI Sequence Viewer  
  AAL35170 (Get FASTA)   NCBI Sequence Viewer  
  AAL35171 (Get FASTA)   NCBI Sequence Viewer  
  AAL35172 (Get FASTA)   NCBI Sequence Viewer  
  AAL35173 (Get FASTA)   NCBI Sequence Viewer  
  AAL35174 (Get FASTA)   NCBI Sequence Viewer  
  AAL35175 (Get FASTA)   NCBI Sequence Viewer  
  AAL35176 (Get FASTA)   NCBI Sequence Viewer  
  AAL35177 (Get FASTA)   NCBI Sequence Viewer  
  AAL35178 (Get FASTA)   NCBI Sequence Viewer  
  AAL35179 (Get FASTA)   NCBI Sequence Viewer  
  AAL35180 (Get FASTA)   NCBI Sequence Viewer  
  AAL35181 (Get FASTA)   NCBI Sequence Viewer  
  AAL35182 (Get FASTA)   NCBI Sequence Viewer  
  AAL35183 (Get FASTA)   NCBI Sequence Viewer  
  AAL35184 (Get FASTA)   NCBI Sequence Viewer  
  AAL35185 (Get FASTA)   NCBI Sequence Viewer  
  AAL35186 (Get FASTA)   NCBI Sequence Viewer  
  AAL35187 (Get FASTA)   NCBI Sequence Viewer  
  AAL35188 (Get FASTA)   NCBI Sequence Viewer  
  AAL35189 (Get FASTA)   NCBI Sequence Viewer  
  AAL35190 (Get FASTA)   NCBI Sequence Viewer  
  AAL35191 (Get FASTA)   NCBI Sequence Viewer  
  AAL35192 (Get FASTA)   NCBI Sequence Viewer  
  AAL35193 (Get FASTA)   NCBI Sequence Viewer  
  AAL35194 (Get FASTA)   NCBI Sequence Viewer  
  AAL35195 (Get FASTA)   NCBI Sequence Viewer  
  AAL35196 (Get FASTA)   NCBI Sequence Viewer  
  AAL35197 (Get FASTA)   NCBI Sequence Viewer  
  AAL35198 (Get FASTA)   NCBI Sequence Viewer  
  AAL35199 (Get FASTA)   NCBI Sequence Viewer  
  AAL35200 (Get FASTA)   NCBI Sequence Viewer  
  AAL35201 (Get FASTA)   NCBI Sequence Viewer  
  AAL35202 (Get FASTA)   NCBI Sequence Viewer  
  AAL35203 (Get FASTA)   NCBI Sequence Viewer  
  AAL35204 (Get FASTA)   NCBI Sequence Viewer  
  AAL35205 (Get FASTA)   NCBI Sequence Viewer  
  AAL35206 (Get FASTA)   NCBI Sequence Viewer  
  AAL35207 (Get FASTA)   NCBI Sequence Viewer  
  AAL35208 (Get FASTA)   NCBI Sequence Viewer  
  AAL35209 (Get FASTA)   NCBI Sequence Viewer  
  AAL35210 (Get FASTA)   NCBI Sequence Viewer  
  AAL35211 (Get FASTA)   NCBI Sequence Viewer  
  AAL35212 (Get FASTA)   NCBI Sequence Viewer  
  AAL35213 (Get FASTA)   NCBI Sequence Viewer  
  AAL58637 (Get FASTA)   NCBI Sequence Viewer  
  AAN73253 (Get FASTA)   NCBI Sequence Viewer  
  AAN73255 (Get FASTA)   NCBI Sequence Viewer  
  AAN73256 (Get FASTA)   NCBI Sequence Viewer  
  AAN73257 (Get FASTA)   NCBI Sequence Viewer  
  AAN73258 (Get FASTA)   NCBI Sequence Viewer  
  AAN73259 (Get FASTA)   NCBI Sequence Viewer  
  AAN73260 (Get FASTA)   NCBI Sequence Viewer  
  AAN73261 (Get FASTA)   NCBI Sequence Viewer  
  AAN73262 (Get FASTA)   NCBI Sequence Viewer  
  AAN73263 (Get FASTA)   NCBI Sequence Viewer  
  AAN73264 (Get FASTA)   NCBI Sequence Viewer  
  ABY87911 (Get FASTA)   NCBI Sequence Viewer  
  AFU07590 (Get FASTA)   NCBI Sequence Viewer  
  BAC05985 (Get FASTA)   NCBI Sequence Viewer  
  BAD00718 (Get FASTA)   NCBI Sequence Viewer  
  BAD00719 (Get FASTA)   NCBI Sequence Viewer  
  BAD00720 (Get FASTA)   NCBI Sequence Viewer  
  EAX02369 (Get FASTA)   NCBI Sequence Viewer  
  P21917 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_000788   ⟸   NM_000797
- UniProtKB: P21917 (UniProtKB/Swiss-Prot),   A0A0G2JM26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000176183   ⟸   ENST00000176183
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:7219189
Promoter ID:EPDNEW_H15340
Type:initiation region
Name:DRD4_1
Description:dopamine receptor D4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811637,285 - 637,345EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_000797.4(DRD4):c.235_247del (p.Ala79fs) deletion Autonomic nervous system dysfunction [RCV000018254]|not provided [RCV001573700] Chr11:637537..637549 [GRCh38]
Chr11:637537..637549 [GRCh37]
Chr11:11p15.5
pathogenic|likely benign
NM_000797.4(DRD4):c.581T>G (p.Val194Gly) single nucleotide variant DOPAMINE RECEPTOR D4 POLYMORPHISM [RCV000018255] Chr11:639830 [GRCh38]
Chr11:639830 [GRCh37]
Chr11:11p15.5
benign
DRD4, 120-BP INS insertion Attention deficit-hyperactivity disorder, susceptibility to [RCV000018256] Chr11:11p15.5 risk factor
GRCh38/hg38 11p15.5-15.4(chr11:196966-3377077)x3 copy number gain See cases [RCV000050947] Chr11:196966..3377077 [GRCh38]
Chr11:196966..3398307 [GRCh37]
Chr11:186966..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-4435344)x3 copy number gain See cases [RCV000050927] Chr11:196966..4435344 [GRCh38]
Chr11:196966..4456574 [GRCh37]
Chr11:186966..4413150 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:218365-3377077)x3 copy number gain See cases [RCV000053614] Chr11:218365..3377077 [GRCh38]
Chr11:218365..3398307 [GRCh37]
Chr11:208365..3354883 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196966-3624139)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053592]|See cases [RCV000053592] Chr11:196966..3624139 [GRCh38]
Chr11:196966..3645369 [GRCh37]
Chr11:186966..3601945 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
NM_000797.4(DRD4):c.1074_1075delinsGG (p.Cys358_Trp359delinsTrpGly) indel not provided [RCV000255881] Chr11:640417..640418 [GRCh38]
Chr11:640417..640418 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh38/hg38 11p15.5-15.1(chr11:446754-18904742)x3 copy number gain See cases [RCV000133997] Chr11:446754..18904742 [GRCh38]
Chr11:446754..18926289 [GRCh37]
Chr11:436754..18882865 [NCBI36]
Chr11:11p15.5-15.1
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:61793-10727969)x3 copy number gain See cases [RCV000139987] Chr11:61793..10727969 [GRCh38]
Chr11:61793..10749516 [GRCh37]
Chr11:51793..10706092 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5-15.4(chr11:196855-5321874)x3 copy number gain See cases [RCV000142890] Chr11:196855..5321874 [GRCh38]
Chr11:196855..5343104 [GRCh37]
Chr11:186855..5299680 [NCBI36]
Chr11:11p15.5-15.4
pathogenic
GRCh38/hg38 11p15.5(chr11:196855-2116185)x3 copy number gain See cases [RCV000142923] Chr11:196855..2116185 [GRCh38]
Chr11:196855..2137415 [GRCh37]
Chr11:186855..2093991 [NCBI36]
Chr11:11p15.5
pathogenic
GRCh37/hg19 11p15.5(chr11:532230-699463)x3 copy number gain See cases [RCV000240134] Chr11:532230..699463 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:193187-5291338)x3 copy number gain See cases [RCV000446036] Chr11:193187..5291338 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NM_000797.4(DRD4):c.1004C>G (p.Ala335Gly) single nucleotide variant not provided [RCV000513781] Chr11:640253 [GRCh38]
Chr11:640253 [GRCh37]
Chr11:11p15.5
benign
NM_000797.4(DRD4):c.860A>C (p.Gln287Pro) single nucleotide variant not provided [RCV001573477] Chr11:640109 [GRCh38]
Chr11:640109 [GRCh37]
Chr11:11p15.5
likely benign
GRCh37/hg19 11p15.5-15.4(chr11:230615-6644927)x3 copy number gain See cases [RCV000449417] Chr11:230615..6644927 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5(chr11:532230-699404)x3 copy number gain See cases [RCV000445988] Chr11:532230..699404 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3 copy number gain See cases [RCV000511561] Chr11:230615..37698540 [GRCh37]
Chr11:11p15.5-12
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-15.3(chr11:193146-12643136) copy number gain Russell-Silver syndrome [RCV000767567] Chr11:193146..12643136 [GRCh37]
Chr11:11p15.5-15.3
pathogenic
GRCh37/hg19 11p15.5-14.3(chr11:230615-25584362)x3 copy number gain See cases [RCV000512225] Chr11:230615..25584362 [GRCh37]
Chr11:11p15.5-14.3
pathogenic
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3 copy number gain See cases [RCV000512477] Chr11:230615..31995219 [GRCh37]
Chr11:11p15.5-13
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3 copy number gain not provided [RCV000683369] Chr11:230615..9704511 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.1(chr11:230615-17099213)x3 copy number gain not provided [RCV000683372] Chr11:230615..17099213 [GRCh37]
Chr11:11p15.5-15.1
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5(chr11:381754-821676)x3 copy number gain not provided [RCV000749876] Chr11:381754..821676 [GRCh37]
Chr11:11p15.5
benign
GRCh37/hg19 11p15.5(chr11:556531-927020)x3 copy number gain not provided [RCV000749890] Chr11:556531..927020 [GRCh37]
Chr11:11p15.5
benign
NC_000011.10:g.(?_532616)_(795026_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001031133] Chr11:532616..795026 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000797.4(DRD4):c.249C>T (p.Leu83=) single nucleotide variant not provided [RCV000929305] Chr11:637553 [GRCh38]
Chr11:637553 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.51G>A (p.Gly17=) single nucleotide variant not provided [RCV000914917] Chr11:637355 [GRCh38]
Chr11:637355 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.744A>C (p.Pro248=) single nucleotide variant not provided [RCV000950756] Chr11:639993 [GRCh38]
Chr11:639993 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.286-7C>T single nucleotide variant not provided [RCV000922172] Chr11:639426 [GRCh38]
Chr11:639426 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.1110G>A (p.Ala370=) single nucleotide variant not provided [RCV000922173] Chr11:640453 [GRCh38]
Chr11:640453 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.126G>A (p.Val42=) single nucleotide variant not provided [RCV000943227] Chr11:637430 [GRCh38]
Chr11:637430 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.222G>A (p.Val74=) single nucleotide variant not provided [RCV000886629] Chr11:637526 [GRCh38]
Chr11:637526 [GRCh37]
Chr11:11p15.5
benign
NM_000797.4(DRD4):c.1194C>T (p.Val398=) single nucleotide variant not provided [RCV000939486] Chr11:640537 [GRCh38]
Chr11:640537 [GRCh37]
Chr11:11p15.5
likely benign
NC_000011.9:g.(?_532616)_(2906985_?)dup duplication Neuronal ceroid lipofuscinosis [RCV001032557] Chr11:532616..2906985 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3 copy number gain not provided [RCV001006372] Chr11:235934..33826995 [GRCh37]
Chr11:11p15.5-13
pathogenic
NM_000797.4(DRD4):c.802G>T (p.Gly268Cys) single nucleotide variant not provided [RCV001573795] Chr11:640051 [GRCh38]
Chr11:640051 [GRCh37]
Chr11:11p15.5
likely benign
NM_000797.4(DRD4):c.31G>C (p.Gly11Arg) single nucleotide variant not provided [RCV000969857] Chr11:637335 [GRCh38]
Chr11:637335 [GRCh37]
Chr11:11p15.5
benign
NM_000797.4(DRD4):c.732T>C (p.Pro244=) single nucleotide variant not provided [RCV000955423] Chr11:639981 [GRCh38]
Chr11:639981 [GRCh37]
Chr11:11p15.5
likely benign
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5
uncertain significance
NM_000797.4(DRD4):c.889C>G (p.Pro297Ala) single nucleotide variant not provided [RCV001573294] Chr11:640138 [GRCh38]
Chr11:640138 [GRCh37]
Chr11:11p15.5
likely benign
GRCh37/hg19 11p15.5(chr11:230615-1150353)x3 copy number gain not provided [RCV001259592] Chr11:230615..1150353 [GRCh37]
Chr11:11p15.5
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:210300-8664358)x3 copy number gain Russell-Silver syndrome [RCV001263222] Chr11:210300..8664358 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
GRCh37/hg19 11p15.5-15.4(chr11:230615-4851537)x3 copy number gain See cases [RCV001263059] Chr11:230615..4851537 [GRCh37]
Chr11:11p15.5-15.4
pathogenic
NC_000011.9:g.(?_612625)_(2193840_?)dup duplication Autosomal recessive DOPA responsive dystonia [RCV001301561]|Immunodeficiency 39 [RCV001033372] Chr11:612625..2193840 [GRCh37]
Chr11:11p15.5
uncertain significance
NC_000011.9:g.(?_298501)_(4113028_?)dup duplication Early infantile epileptic encephalopathy with suppression bursts [RCV001316682] Chr11:298501..4113028 [GRCh37]
Chr11:11p15.5-15.4
uncertain significance
GRCh37/hg19 11p15.5-15.4(chr11:10701-5080415)x2 copy number gain See cases [RCV001310286] Chr11:10701..5080415 [GRCh37]
Chr11:11p15.5-15.4
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3025 AgrOrtholog
COSMIC DRD4 COSMIC
Ensembl Genes ENSG00000069696 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000276825 UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000176183 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000478431 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000176183 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000611962 UniProtKB/Swiss-Prot
GTEx ENSG00000069696 GTEx
  ENSG00000276825 GTEx
HGNC ID HGNC:3025 ENTREZGENE
Human Proteome Map DRD4 Human Proteome Map
InterPro Dopamine_D4_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dopamine_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:1815 UniProtKB/Swiss-Prot
NCBI Gene 1815 ENTREZGENE
OMIM 126452 OMIM
  143465 OMIM
PANTHER PTHR24248:SF143 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot
PharmGKB DRD4 RGD, PharmGKB
PRINTS DOPAMINED4R UniProtKB/Swiss-Prot
  DOPAMINER UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
UniProt A0A0G2JM26 ENTREZGENE
  A4LB49_HUMAN UniProtKB/TrEMBL
  A4LB54_HUMAN UniProtKB/TrEMBL
  A4LB56_HUMAN UniProtKB/TrEMBL
  A4LBB9_HUMAN UniProtKB/TrEMBL
  DRD4_HUMAN UniProtKB/Swiss-Prot
  F6K0T3_HUMAN UniProtKB/TrEMBL
  F6K0T7_HUMAN UniProtKB/TrEMBL
  F6K0T8_HUMAN UniProtKB/TrEMBL
  F6K0T9_HUMAN UniProtKB/TrEMBL
  F6K0U0_HUMAN UniProtKB/TrEMBL
  G5CTX6_HUMAN UniProtKB/TrEMBL
  G9HV62_HUMAN UniProtKB/TrEMBL
  G9HV63_HUMAN UniProtKB/TrEMBL
  G9HV64_HUMAN UniProtKB/TrEMBL
  G9HV65_HUMAN UniProtKB/TrEMBL
  K9MAQ3_HUMAN UniProtKB/TrEMBL
  K9MAQ4_HUMAN UniProtKB/TrEMBL
  K9MAQ5_HUMAN UniProtKB/TrEMBL
  K9MAU6_HUMAN UniProtKB/TrEMBL
  K9MAU8_HUMAN UniProtKB/TrEMBL
  K9MAZ0_HUMAN UniProtKB/TrEMBL
  K9MAZ1_HUMAN UniProtKB/TrEMBL
  K9MB44_HUMAN UniProtKB/TrEMBL
  K9MB45_HUMAN UniProtKB/TrEMBL
  K9MB71_HUMAN UniProtKB/TrEMBL
  K9MB72_HUMAN UniProtKB/TrEMBL
  P21917 ENTREZGENE
  Q0MTB8_HUMAN UniProtKB/TrEMBL
  Q0MTB9_HUMAN UniProtKB/TrEMBL
  Q76E76_HUMAN UniProtKB/TrEMBL
  Q8IZB1_HUMAN UniProtKB/TrEMBL
  Q8IZB2_HUMAN UniProtKB/TrEMBL
  Q8IZB3_HUMAN UniProtKB/TrEMBL
  Q8IZB4_HUMAN UniProtKB/TrEMBL
  Q8IZB5_HUMAN UniProtKB/TrEMBL
  Q8IZB6_HUMAN UniProtKB/TrEMBL
  Q8IZB7_HUMAN UniProtKB/TrEMBL
  Q8IZB8_HUMAN UniProtKB/TrEMBL
  Q8IZB9_HUMAN UniProtKB/TrEMBL
  Q8IZC0_HUMAN UniProtKB/TrEMBL
  Q8WTQ0_HUMAN UniProtKB/TrEMBL
  Q8WTQ5_HUMAN UniProtKB/TrEMBL
  Q8WTR3_HUMAN UniProtKB/TrEMBL
  Q8WTR5_HUMAN UniProtKB/TrEMBL
  Q8WTR9_HUMAN UniProtKB/TrEMBL
  Q8WTS5_HUMAN UniProtKB/TrEMBL
  Q8WTS7_HUMAN UniProtKB/TrEMBL
  Q8WTT3_HUMAN UniProtKB/TrEMBL
  Q8WTT6_HUMAN UniProtKB/TrEMBL
  Q8WTT7_HUMAN UniProtKB/TrEMBL
  Q8WXL5_HUMAN UniProtKB/TrEMBL
  Q8WXL6_HUMAN UniProtKB/TrEMBL
  Q8WXL7_HUMAN UniProtKB/TrEMBL
  Q8WXL8_HUMAN UniProtKB/TrEMBL
  Q8WXL9_HUMAN UniProtKB/TrEMBL
  Q8WXM0_HUMAN UniProtKB/TrEMBL
  Q8WXM1_HUMAN UniProtKB/TrEMBL
  Q8WXM3_HUMAN UniProtKB/TrEMBL
  Q8WXM4_HUMAN UniProtKB/TrEMBL
  Q8WXM5_HUMAN UniProtKB/TrEMBL
  Q8WXM6_HUMAN UniProtKB/TrEMBL
  Q8WXM7_HUMAN UniProtKB/TrEMBL
  Q8WXM8_HUMAN UniProtKB/TrEMBL
  Q8WXM9_HUMAN UniProtKB/TrEMBL
  Q8WXN0_HUMAN UniProtKB/TrEMBL
  Q8WXN1_HUMAN UniProtKB/TrEMBL
  Q8WXN2_HUMAN UniProtKB/TrEMBL
  Q8WXN3_HUMAN UniProtKB/TrEMBL
  Q8WXN4_HUMAN UniProtKB/TrEMBL
  Q8WXN5_HUMAN UniProtKB/TrEMBL
  Q8WXN6_HUMAN UniProtKB/TrEMBL
  Q8WXN7_HUMAN UniProtKB/TrEMBL
  Q8WXN8_HUMAN UniProtKB/TrEMBL
  Q8WXN9_HUMAN UniProtKB/TrEMBL
  Q8WXP0_HUMAN UniProtKB/TrEMBL
  Q8WXP1_HUMAN UniProtKB/TrEMBL
  Q8WXP2_HUMAN UniProtKB/TrEMBL
  Q8WXP3_HUMAN UniProtKB/TrEMBL
  Q8WXP4_HUMAN UniProtKB/TrEMBL
  Q8WXP5_HUMAN UniProtKB/TrEMBL
  Q8WXP6_HUMAN UniProtKB/TrEMBL
  Q8WXP7_HUMAN UniProtKB/TrEMBL
UniProt Secondary B0M0J7 UniProtKB/Swiss-Prot
  Q7Z7Q5 UniProtKB/Swiss-Prot
  Q8NGM5 UniProtKB/Swiss-Prot
  Q8WXM2 UniProtKB/TrEMBL