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Gene: H1-0 (H1.0 linker histone) Homo sapiens
Symbol: H1-0
Name: H1.0 linker histone
Description: Exhibits chromatin DNA binding activity. Involved in chromatin silencing; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription regulatory region DNA binding activity. Localizes to several cellular components, including Golgi apparatus; nuclear lumen; and transcription repressor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H1 histone family member 0; H1 histone family, member 0; H1.0; H1.0, H1(0), H1-0; H10; H1F0; H1FV; histone H1'; histone H1(0); histone H1.0; MGC5241
Mus musculus (house mouse) : H1f0 (H1.0 linker histone)  MGI  Alliance
Rattus norvegicus (Norway rat) : H1f0 (H1 histone family, member 0)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010789 (histone H1.0)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100970460 (histone H1.0)
Canis lupus familiaris (dog) : H1-0 (H1.0 linker histone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970440 (histone H1.0)
Sus scrofa (pig) : LOC100510904 (histone H1.0)
Chlorocebus sabaeus (African green monkey) : H1F0 (H1 histone family member 0)
Heterocephalus glaber (naked mole-rat) : LOC101717518 (histone H1.0)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2237,805,093 - 37,807,436 (+)EnsemblGRCh38hg38GRCh38
GRCh382237,805,229 - 37,807,432 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372238,201,114 - 38,203,443 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,531,060 - 36,533,389 (+)NCBINCBI36hg18NCBI36
Build 342236,525,673 - 36,527,943NCBI
Celera2222,002,906 - 22,005,235 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2221,168,152 - 21,170,440 (+)NCBIHuRef
CHM1_12238,159,864 - 38,162,193 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on H1-0
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736127
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.