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Gene: Clcnkb (chloride channel, voltage-sensitive Kb) Mus musculus
Symbol: Clcnkb
Name: chloride channel, voltage-sensitive Kb
RGD ID: 736096
Description: Predicted to have identical protein binding activity and voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to localize to integral component of plasma membrane. Is expressed in early conceptus; metanephros; and oocyte. Used to study Bartter disease and Bartter disease type 3. Human ortholog(s) of this gene implicated in Bartter disease type 3; Bartter disease type 4b; Gitelman syndrome; and hypertension. Orthologous to human CLCNKB (chloride voltage-gated channel Kb).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chloride channel K1-like; chloride channel Kb; chloride channel protein ClC-Kb; ClC-K; clC-K2; Clc-Ka; Clck; Clck2; CLCKB; Clcn; Clcnk1l; Clcnk2; putative basolateral cTAL chloride channel ClC-Ka; putative basolateral mTAL chloride channel ClC-Ka
Homo sapiens (human) : CLCNKB (chloride voltage-gated channel Kb)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcnkb (chloride voltage-gated channel Kb)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLCNKB (chloride voltage-gated channel Kb)
Canis lupus familiaris (dog) : CLCNKA (chloride voltage-gated channel Ka)
Chlorocebus sabaeus (African green monkey) : CLCNKB (chloride voltage-gated channel Kb)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394141,131,668 - 141,143,440 (-)NCBI
GRCm384141,404,357 - 141,416,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,404,353 - 141,416,014 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,960,272 - 140,971,903 (-)NCBIGRCm37mm9NCBIm37
MGSCv364140,676,436 - 140,688,057 (-)NCBImm8
Celera4143,220,859 - 143,232,479 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Clcnkb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736096
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.