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Gene: Clcnkb (chloride channel, voltage-sensitive Kb) Mus musculus
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Symbol: Clcnkb
Name: chloride channel, voltage-sensitive Kb
RGD ID: 736096
Description: Predicted to have identical protein binding activity and voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to localize to integral component of plasma membrane. Is expressed in early conceptus; metanephros; and oocyte. Used to study Bartter disease and Bartter disease type 3. Human ortholog(s) of this gene implicated in Bartter disease type 3; Bartter disease type 4b; Gitelman syndrome; and hypertension. Orthologous to human CLCNKB (chloride voltage-gated channel Kb).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chloride channel K1-like; chloride channel Kb; chloride channel protein ClC-Kb; ClC-K; clC-K2; Clc-Ka; Clck; Clck2; CLCKB; Clcn; Clcnk1l; Clcnk2; putative basolateral cTAL chloride channel ClC-Ka; putative basolateral mTAL chloride channel ClC-Ka
Orthologs:
Homo sapiens (human) : CLCNKB (chloride voltage-gated channel Kb)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcnkb (chloride voltage-gated channel Kb)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLCNKB (chloride voltage-gated channel Kb)
Canis lupus familiaris (dog) : CLCNKA (chloride voltage-gated channel Ka)
Chlorocebus sabaeus (African green monkey) : CLCNKB (chloride voltage-gated channel Kb)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,131,668 - 141,143,440 (-)NCBI
GRCm384141,404,357 - 141,416,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,404,353 - 141,416,014 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,960,272 - 140,971,903 (-)NCBIGRCm37mm9NCBIm37
MGSCv364140,676,436 - 140,688,057 (-)NCBImm8
Celera4143,220,859 - 143,232,479 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Clcnkb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736096
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.