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Gene: Gnaz (guanine nucleotide binding protein, alpha z subunit) Mus musculus
Symbol: Gnaz
Name: guanine nucleotide binding protein, alpha z subunit
Description: Predicted to have G protein-coupled serotonin receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Localizes to the cell body and dendrite. Is expressed in brain; early conceptus; early tubule; ganglia; and gonad. Orthologous to human GNAZ (G protein subunit alpha z); PARTICIPATES IN endothelin signaling pathway; Hedgehog signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI847979; g(x) alpha chain; guanine nucleotide-binding protein G(z) subunit alpha; Gz; gz-alpha
Homo sapiens (human) : GNAZ (G protein subunit alpha z)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnaz (G protein subunit alpha z)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnaz (G protein subunit alpha z)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAZ (G protein subunit alpha z)
Canis lupus familiaris (dog) : GNAZ (G protein subunit alpha z)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnaz (G protein subunit alpha z)
Sus scrofa (pig) : GNAZ (G protein subunit alpha z)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381074,967,177 - 75,016,907 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371074,429,976 - 74,478,622 (+)NCBIGRCm37mm9NCBIm37
MGSCv361074,410,947 - 74,459,593 (+)NCBImm8
Celera1076,015,010 - 76,063,654 (+)NCBICelera
Cytogenetic Map10 C1NCBI
cM Map1038.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gnaz
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736020
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.