Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CPLX1 (complexin 1) Homo sapiens
Analyze
Symbol: CPLX1
Name: complexin 1
Description: Predicted to have syntaxin-1 binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to localize to SNARE complex; neuronal cell body; and terminal bouton. Implicated in early infantile epileptic encephalopathy 63.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: complexin I; complexin-1; CPX I; CPX-I; CPX1; EIEE63; synaphin 2; synaphin-2
Orthologs:
Mus musculus (house mouse) : Cplx1 (complexin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cplx1 (complexin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cplx1 (complexin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CPLX1 (complexin 1)
Canis lupus familiaris (dog) : CPLX1 (complexin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cplx1 (complexin 1)
Sus scrofa (pig) : CPLX1 (complexin 1)
Chlorocebus sabaeus (African green monkey) : CPLX1 (complexin 1)
Heterocephalus glaber (naked mole-rat) : Cplx1 (complexin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4784,957 - 826,129 (-)EnsemblGRCh38hg38GRCh38
GRCh384784,957 - 826,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374778,745 - 819,945 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364768,745 - 809,945 (-)NCBINCBI36hg18NCBI36
Build 344768,575 - 809,775NCBI
Celera4715,373 - 756,500 (-)NCBI
Cytogenetic Map4p16.3NCBI
HuRef4749,326 - 788,854 (-)NCBIHuRef
CHM1_14775,692 - 816,930 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CPLX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735999
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.