Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit) Homo sapiens
Analyze
Symbol: CHRNA2
Name: cholinergic receptor nicotinic alpha 2 subunit
Description: Exhibits acetylcholine receptor activity and acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine binding activity and extracellular ligand-gated ion channel activity. Involved in signal transduction. Localizes to the acetylcholine-gated channel complex. Implicated in autosomal dominant nocturnal frontal lobe epilepsy 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acetylcholine receptor, nicotinic, alpha 2 (neuronal); cholinergic receptor, nicotinic alpha 2; cholinergic receptor, nicotinic, alpha 2 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal); neuronal acetylcholine receptor subunit alpha-2
Orthologs:
Mus musculus (house mouse) : Chrna2 (cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal))  MGI  Alliance
Rattus norvegicus (Norway rat) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Canis lupus familiaris (dog) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
Sus scrofa (pig) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit)
Heterocephalus glaber (naked mole-rat) : Chrna2 (cholinergic receptor nicotinic alpha 2 subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl827,459,756 - 27,479,883 (-)Ensembl
GRCh38827,459,756 - 27,479,285 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37827,317,278 - 27,336,813 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,373,195 - 27,392,730 (-)NCBINCBI36hg18NCBI36
Build 34827,374,181 - 27,392,675NCBI
Celera826,277,396 - 26,296,925 (-)NCBI
Cytogenetic Map8p21.2NCBI
HuRef825,862,340 - 25,881,872 (-)NCBIHuRef
CHM1_1827,519,147 - 27,538,678 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CHRNA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735907
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.