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Gene: Acan (aggrecan) Mus musculus
Symbol: Acan
Name: aggrecan
Description: Predicted to have calcium ion binding activity. Involved in several processes, including cartilage development; collagen fibril organization; and proteoglycan biosynthetic process. Localizes to several cellular components, including the GABA-ergic synapse; glutamatergic synapse; and perisynaptic extracellular matrix. Used to study achondroplasia. Is expressed in several structures, including brain; embryo mesenchyme; limb; sensory organ; and skeleton. Orthologous to human ACAN (aggrecan); INTERACTS WITH 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Agc; Agc1; aggrecan 1; aggrecan core protein; b2b183Clo; cartilage-specific proteoglycan core protein; cmd; CSPCP; Cspg1
Homo sapiens (human) : ACAN (aggrecan)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acan (aggrecan)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acan (aggrecan)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAN (aggrecan)
Canis lupus familiaris (dog) : ACAN (aggrecan)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acan (aggrecan)
Sus scrofa (pig) : ACAN (aggrecan)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl779,053,483 - 79,115,099 (+)Ensembl
GRCm38779,053,226 - 79,115,099 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37786,198,369 - 86,259,985 (+)NCBIGRCm37mm9NCBIm37
MGSCv36778,926,996 - 78,988,612 (+)NCBImm8
Celera776,452,812 - 76,514,796 (+)NCBICelera
Cytogenetic Map7 D2NCBI
cM Map744.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Acan
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735902
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.