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Gene: Acan (aggrecan) Mus musculus
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Symbol: Acan
Name: aggrecan
Description: Predicted to have calcium ion binding activity. Involved in several processes, including cartilage development; collagen fibril organization; and proteoglycan biosynthetic process. Localizes to several cellular components, including the GABA-ergic synapse; glutamatergic synapse; and perisynaptic extracellular matrix. Used to study achondroplasia. Is expressed in several structures, including brain; embryo mesenchyme; limb; sensory organ; and skeleton. Orthologous to human ACAN (aggrecan); INTERACTS WITH 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Agc; Agc1; aggrecan 1; aggrecan core protein; b2b183Clo; cartilage-specific proteoglycan core protein; cmd; CSPCP; Cspg1
Orthologs:
Homo sapiens (human) : ACAN (aggrecan)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acan (aggrecan)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acan (aggrecan)
Pan paniscus (bonobo/pygmy chimpanzee) : ACAN (aggrecan)
Canis lupus familiaris (dog) : ACAN (aggrecan)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acan (aggrecan)
Sus scrofa (pig) : ACAN (aggrecan)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl779,053,483 - 79,115,099 (+)Ensembl
GRCm38779,053,226 - 79,115,099 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37786,198,369 - 86,259,985 (+)NCBIGRCm37mm9NCBIm37
MGSCv36778,926,996 - 78,988,612 (+)NCBImm8
Celera776,452,812 - 76,514,796 (+)NCBICelera
Cytogenetic Map7 D2NCBI
cM Map744.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acan
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735902
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.