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Gene: Nrxn2 (neurexin II) Mus musculus
Symbol: Nrxn2
Name: neurexin II
Description: Exhibits several functions, including calcium channel regulator activity; cell adhesion molecule binding activity; and neuroligin family protein binding activity. Involved in several processes, including neurotransmitter secretion; postsynapse assembly; and postsynaptic density protein 95 clustering. Localizes to the protein-containing complex. Used to study autism spectrum disorder. Is expressed in blood vessel; brain; and retina. Orthologous to human NRXN2 (neurexin 2); INTERACTS WITH 3-methylcholanthrene; 4,4'-sulfonyldiphenol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6430591O13Rik; mKIAA0921; neurexin II alpha; neurexin II beta; neurexin-2; neurexin-2-alpha; neurexin-2-beta
Homo sapiens (human) : NRXN2 (neurexin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nrxn2 (neurexin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrxn2 (neurexin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NRXN2 (neurexin 2)
Canis lupus familiaris (dog) : NRXN2 (neurexin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrxn2 (neurexin 2)
Sus scrofa (pig) : NRXN2 (neurexin 2)
Chlorocebus sabaeus (African green monkey) : NRXN2 (neurexin 2)
Heterocephalus glaber (naked mole-rat) : Nrxn2 (neurexin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl196,418,731 - 6,544,169 (+)Ensembl
GRCm38196,418,756 - 6,533,217 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,428,016 - 6,533,217 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,428,016 - 6,533,217 (+)NCBImm8
Celera196,291,755 - 6,405,941 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nrxn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735901
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.