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Gene: CD38 (CD38 molecule) Homo sapiens
Symbol: CD38
Name: CD38 molecule
Description: Predicted to have NAD+ nucleosidase activity and phosphorus-oxygen lyase activity. Involved in several processes, including B cell receptor signaling pathway; positive regulation of B cell proliferation; and regulation of transcription, DNA-templated. Localizes to extracellular exosome. Implicated in type 1 diabetes mellitus and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADPRC 1; ADPRC1; cADPr hydrolase 1; cd38 antigen; CD38 antigen (p45); cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; NAD(+) nucleosidase; T10
Mus musculus (house mouse) : Cd38 (CD38 antigen)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd38 (CD38 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd38 (CD38 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD38 (CD38 molecule)
Canis lupus familiaris (dog) : CD38 (CD38 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd38 (CD38 molecule)
Sus scrofa (pig) : CD38 (CD38 molecule)
Chlorocebus sabaeus (African green monkey) : CD38 (CD38 molecule)
Heterocephalus glaber (naked mole-rat) : Cd38 (CD38 molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl415,778,275 - 15,853,232 (+)EnsemblGRCh38hg38GRCh38
GRCh38415,778,328 - 15,853,232 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37415,779,921 - 15,850,706 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,389,029 - 15,459,806 (+)NCBINCBI36hg18NCBI36
Build 34415,456,199 - 15,526,975NCBI
Celera416,244,567 - 16,315,338 (+)NCBI
Cytogenetic Map4p15.32NCBI
HuRef415,130,537 - 15,200,389 (+)NCBIHuRef
CHM1_1415,777,918 - 15,852,923 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CD38
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735841
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.