Trpv4 (transient receptor potential cation channel, subfamily V, member 4) - Rat Genome Database

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Gene: Trpv4 (transient receptor potential cation channel, subfamily V, member 4) Mus musculus
Analyze
Symbol: Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
RGD ID: 735797
MGI Page MGI
Description: Enables several functions, including SH2 domain binding activity; calcium channel activity; and osmosensor activity. Involved in several processes, including cellular hypotonic salinity response; positive regulation of MAPK cascade; and positive regulation of cytokine production. Acts upstream of or within several processes, including hyperosmotic salinity response; osmosensory signaling pathway; and vasopressin secretion. Located in adherens junction; cilium; and plasma membrane. Is expressed in several structures, including autopod; brain; respiratory system; sensory organ; and skeleton. Used to study autosomal dominant nonsyndromic deafness 25. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2C; motor neuron disease (multiple); osteochondrodysplasia (multiple); and osteonecrosis. Orthologous to human TRPV4 (transient receptor potential cation channel subfamily V member 4).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610033B08Rik; MGC150050; osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; OTR; OTRPC4; transient receptor potential cation channel subfamily V member 4; transient receptor potential protein 12; Trp; Trp12; trpv4 channel; V; vanilloid receptor-like channel 2; vanilloid receptor-like protein 2; vanilloid receptor-related osmotically-activated channel; VR; VR-OAC; VRL-2; VROAC
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,760,213 - 114,796,497 (-)NCBIGRCm39mm39
GRCm39 Ensembl5114,760,213 - 114,796,482 (-)Ensembl
GRCm385114,622,152 - 114,658,435 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,622,152 - 114,658,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,072,163 - 115,108,430 (-)NCBIGRCm37mm9NCBIm37
MGSCv365114,883,153 - 114,919,388 (-)NCBImm8
Celera5111,719,696 - 111,755,858 (-)NCBICelera
Cytogenetic Map5FNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aldehydo-D-glucosamine  (EXP)
ammonium chloride  (ISO)
arachidonic acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-D-glucosamine  (EXP)
bisphenol A  (EXP,ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
Cannabichromene  (EXP)
cannabidiol  (ISO)
Cannabidivarin  (ISO)
capsaicin  (ISO)
choline  (EXP)
chrysene  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dibenz[a,h]anthracene  (EXP)
diuron  (ISO)
ethanol  (ISO)
fipronil  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
furan  (ISO)
gadolinium atom  (ISO)
gentamycin  (ISO)
glycidol  (ISO)
icosanoid  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
indometacin  (ISO)
ionomycin  (ISO)
ketamine  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
prostaglandin E2  (EXP)
ruthenium red  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
serotonin  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium atom  (ISO)
streptozocin  (ISO)
tetraphene  (EXP)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
triptonide  (EXP)
troglitazone  (EXP)
vincristine  (ISO)
zalcitabine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton reorganization  (ISO)
actin filament organization  (IBA,ISO)
ATP export  (ISO)
ATP transport  (ISO)
blood vessel endothelial cell delamination  (ISO)
calcium ion import  (IDA,ISO)
calcium ion import across plasma membrane  (IBA)
calcium ion import into cytosol  (ISO)
calcium ion transmembrane transport  (ISO)
calcium ion transport  (ISO)
cartilage development involved in endochondral bone morphogenesis  (ISO)
cartilage homeostasis  (ISO)
cell-cell junction assembly  (IMP)
cellular calcium ion homeostasis  (IMP,ISO)
cellular hypotonic response  (IDA,ISO)
cellular hypotonic salinity response  (IMP)
cellular response to heat  (IMP)
cellular response to osmotic stress  (IMP)
cortical microtubule organization  (ISO)
diet induced thermogenesis  (IMP)
energy homeostasis  (IMP)
glucose homeostasis  (IMP)
hyperosmotic salinity response  (IMP)
hypotonic response  (ISO)
ion transport  (IEA)
microtubule polymerization  (ISO)
multicellular organismal water homeostasis  (ISO)
negative regulation of brown fat cell differentiation  (IMP)
negative regulation of cell volume  (ISO)
negative regulation of neuron projection development  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP)
osmosensory signaling pathway  (IBA,IDA,IMP)
positive regulation of chemokine (C-C motif) ligand 5 production  (IMP)
positive regulation of chemokine (C-X-C motif) ligand 1 production  (IMP)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IMP)
positive regulation of gene expression  (IMP)
positive regulation of inflammatory response  (IMP)
positive regulation of interleukin-6 production  (IMP)
positive regulation of intracellular protein transport  (ISO)
positive regulation of JNK cascade  (IMP)
positive regulation of macrophage chemotaxis  (IMP)
positive regulation of macrophage inflammatory protein 1 alpha production  (IMP)
positive regulation of membrane hyperpolarization  (ISO)
positive regulation of microtubule depolymerization  (ISO)
positive regulation of monocyte chemotactic protein-1 production  (IMP)
positive regulation of P-type sodium:potassium-exchanging transporter activity  (ISO)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein tyrosine kinase activity  (ISO)
positive regulation of striated muscle contraction  (ISO)
positive regulation of vascular permeability  (IMP,ISO)
regulation of aerobic respiration  (IMP)
regulation of blood pressure  (ISO)
regulation of heart rate  (ISO)
regulation of p38MAPK cascade  (IMP)
regulation of response to osmotic stress  (IMP,ISO)
relaxation of vascular associated smooth muscle  (ISO)
response to fatty acid  (IMP)
response to insulin  (IMP)
response to lipopolysaccharide  (IMP)
response to osmotic stress  (IDA,IPI)
transmembrane transport  (IEA)
vasopressin secretion  (IMP)

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11025659   PMID:11042159   PMID:11076861   PMID:11094154   PMID:11827975   PMID:12093812   PMID:12354759   PMID:12477932   PMID:12538589   PMID:12692122  
PMID:12738791   PMID:12777254   PMID:12783886   PMID:12879072   PMID:14517216   PMID:14581612   PMID:14665413   PMID:14691263   PMID:14707014   PMID:15004014   PMID:15187078   PMID:15689568  
PMID:15858826   PMID:15925108   PMID:15952033   PMID:16141072   PMID:16141073   PMID:16179585   PMID:16407759   PMID:16460286   PMID:16571723   PMID:16597741   PMID:16602821   PMID:16627472  
PMID:16899456   PMID:16940152   PMID:16954339   PMID:17008604   PMID:17110928   PMID:17124270   PMID:17301165   PMID:17341586   PMID:17660328   PMID:17699550   PMID:17786199   PMID:17804410  
PMID:17932042   PMID:17948126   PMID:17962608   PMID:17967183   PMID:18024594   PMID:18174177   PMID:18234883   PMID:18264976   PMID:18305162   PMID:18323527   PMID:18325985   PMID:18343379  
PMID:18456412   PMID:18565335   PMID:18607942   PMID:18682435   PMID:18682499   PMID:18695040   PMID:18719094   PMID:18751967   PMID:18754773   PMID:18762026   PMID:19029406   PMID:19033444  
PMID:19164517   PMID:19188524   PMID:19272164   PMID:19322198   PMID:19439599   PMID:19531473   PMID:19617313   PMID:19617407   PMID:19834762   PMID:19839244   PMID:19966050   PMID:20015940  
PMID:20059953   PMID:20093626   PMID:20136846   PMID:20385965   PMID:20399209   PMID:20413591   PMID:20539005   PMID:20562229   PMID:20583100   PMID:20682256   PMID:20888819   PMID:20924600  
PMID:20956320   PMID:21166676   PMID:21262470   PMID:21262839   PMID:21267068   PMID:21540339   PMID:21562271   PMID:21586160   PMID:21606493   PMID:21677750   PMID:21705673   PMID:21763756  
PMID:21850238   PMID:21873635   PMID:21883699   PMID:21930300   PMID:21994383   PMID:22051675   PMID:22133806   PMID:22187434   PMID:22204737   PMID:22207590   PMID:22207724   PMID:22298783  
PMID:22300296   PMID:22442563   PMID:22492541   PMID:22556255   PMID:22785252   PMID:22814746   PMID:22865090   PMID:22882778   PMID:23021218   PMID:23086916   PMID:23136043   PMID:23147107  
PMID:23178209   PMID:23288842   PMID:23314072   PMID:23457335   PMID:23530219   PMID:23709216   PMID:23726674   PMID:23739180   PMID:23799042   PMID:23826708   PMID:23889563   PMID:23929777  
PMID:23977387   PMID:24084385   PMID:24155319   PMID:24509911   PMID:24737318   PMID:24744878   PMID:24759099   PMID:24762817   PMID:24789205   PMID:24838754   PMID:24952961   PMID:25005230  
PMID:25069877   PMID:25100078   PMID:25114176   PMID:25118282   PMID:25143588   PMID:25150065   PMID:25240613   PMID:25281928   PMID:25351988   PMID:25365224   PMID:25382142   PMID:25399955  
PMID:25411497   PMID:25421636   PMID:25501034   PMID:25535917   PMID:25572823   PMID:25604429   PMID:25637662   PMID:25681460   PMID:25739906   PMID:25752528   PMID:25761879   PMID:25867067  
PMID:26006045   PMID:26043006   PMID:26043075   PMID:26207981   PMID:26222277   PMID:26250433   PMID:26314785   PMID:26388427   PMID:26413835   PMID:26424736   PMID:26424896   PMID:26475857  
PMID:26597012   PMID:26702092   PMID:26760501   PMID:26763435   PMID:26792207   PMID:26961876   PMID:27006502   PMID:27029071   PMID:27180924   PMID:27247148   PMID:27252474   PMID:27291497  
PMID:27350729   PMID:27364478   PMID:27388701   PMID:27436359   PMID:27491796   PMID:27496898   PMID:27510430   PMID:27660267   PMID:27706112   PMID:27779758   PMID:27820600   PMID:27861175  
PMID:27889423   PMID:27908695   PMID:27913210   PMID:28030558   PMID:28060940   PMID:28073835   PMID:28135189   PMID:28143710   PMID:28158279   PMID:28187982   PMID:28249987   PMID:28274924  
PMID:28526784   PMID:28602913   PMID:28639721   PMID:28807414   PMID:28899928   PMID:28947806   PMID:29018170   PMID:29056552   PMID:29057902   PMID:29124201   PMID:29175331   PMID:29187363  
PMID:29301784   PMID:29491434   PMID:29559678   PMID:29604963   PMID:29632308   PMID:29721987   PMID:29733975   PMID:29791836   PMID:29793978   PMID:29931225   PMID:29958798   PMID:29976627  
PMID:29985973   PMID:30084828   PMID:30143574   PMID:30153398   PMID:30207167   PMID:30365528   PMID:30367945   PMID:30401632   PMID:30413814   PMID:30450767   PMID:30508606   PMID:30629470  
PMID:30838874   PMID:30842533   PMID:31040368   PMID:31048895   PMID:31121133   PMID:31207191   PMID:31229503   PMID:31285329   PMID:31295806   PMID:31299321   PMID:31313950   PMID:31417159  
PMID:31487269   PMID:31597314   PMID:31603369   PMID:31641226   PMID:31693106   PMID:31693393   PMID:31719171   PMID:31760763   PMID:31770754   PMID:31791130   PMID:31836532   PMID:31851715  
PMID:31896814   PMID:31911949   PMID:31925567   PMID:31969384   PMID:31999644   PMID:32004565   PMID:32008372   PMID:32073873   PMID:32235694   PMID:32341518   PMID:32399392   PMID:32418267  
PMID:32435246   PMID:32477057   PMID:32493776   PMID:32535021   PMID:32542737   PMID:32555397   PMID:32647282   PMID:32734537   PMID:32736678   PMID:32801314   PMID:32931478   PMID:33051259  
PMID:33078410   PMID:33131246   PMID:33247229   PMID:33262217   PMID:33317522   PMID:33381111   PMID:33387462   PMID:33399853   PMID:33449852   PMID:33467654   PMID:33819485   PMID:33853948  
PMID:33859334   PMID:33879616   PMID:33884443   PMID:33888579   PMID:34116738   PMID:34490843   PMID:34663597   PMID:34673834   PMID:34804016   PMID:34884463  


Genomics

Comparative Map Data
Trpv4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,760,213 - 114,796,497 (-)NCBIGRCm39mm39
GRCm39 Ensembl5114,760,213 - 114,796,482 (-)Ensembl
GRCm385114,622,152 - 114,658,435 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,622,152 - 114,658,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv375115,072,163 - 115,108,430 (-)NCBIGRCm37mm9NCBIm37
MGSCv365114,883,153 - 114,919,388 (-)NCBImm8
Celera5111,719,696 - 111,755,858 (-)NCBICelera
Cytogenetic Map5FNCBI
TRPV4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12109,783,087 - 109,833,406 (-)EnsemblGRCh38hg38GRCh38
GRCh3812109,783,087 - 109,833,398 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712110,220,892 - 110,271,203 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,705,277 - 108,755,595 (-)NCBINCBI36hg18NCBI36
Celera12109,845,179 - 109,895,568 (-)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12107,237,035 - 107,287,147 (-)NCBIHuRef
CHM1_112110,188,702 - 110,239,020 (-)NCBICHM1_1
Trpv4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21241,938,533 - 41,977,517 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1241,938,560 - 41,977,517 (+)Ensembl
Rnor_6.01247,698,915 - 47,737,902 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,698,947 - 47,737,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01249,492,064 - 49,529,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,226,933 - 43,265,889 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11243,090,320 - 43,129,277 (+)NCBI
Celera1243,552,408 - 43,590,250 (+)NCBICelera
Cytogenetic Map12q16NCBI
Trpv4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554558,744,176 - 8,783,741 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554558,744,865 - 8,781,644 (+)NCBIChiLan1.0ChiLan1.0
TRPV4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112110,754,238 - 110,786,182 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,754,238 - 110,786,182 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012107,359,005 - 107,409,359 (-)NCBIMhudiblu_PPA_v0panPan3
TRPV4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,293,334 - 17,330,156 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,262,100 - 17,330,165 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2618,472,505 - 18,493,002 (-)NCBI
ROS_Cfam_1.02617,652,672 - 17,673,399 (+)NCBI
ROS_Cfam_1.0 Ensembl2617,652,672 - 17,673,984 (+)Ensembl
UMICH_Zoey_3.12618,683,516 - 18,704,163 (-)NCBI
UNSW_CanFamBas_1.02617,643,537 - 17,664,298 (+)NCBI
UU_Cfam_GSD_1.02617,660,529 - 17,681,097 (+)NCBI
Trpv4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,028,138 - 144,051,340 (+)NCBI
SpeTri2.0NW_0049367691,424,526 - 1,447,547 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPV4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,125,869 - 41,169,582 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,125,819 - 41,169,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21443,641,455 - 43,683,549 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRPV4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,020,972 - 105,072,660 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037140,046,822 - 140,098,634 (+)NCBIVero_WHO_p1.0
Trpv4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474710,675,625 - 10,685,351 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Trpv4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385114,626,743 - 114,626,859UniSTSGRCm38
MGSCv375115,076,752 - 115,076,868UniSTSGRCm37
Celera5111,725,022 - 111,725,138UniSTS
Cytogenetic Map5FUniSTS
cM Map555.99UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526236236138457140Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554342835126924008Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)569900000132500000Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572700000140000000Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574300000132500000Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574300000132500000Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575154687119880564Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580701400114701400Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined580871790114871944Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582690609116690738Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582690609116690738Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587239005121239199Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587239005121239199Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587239005121239199Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587239005121239199Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587239005121239199Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589271017118725963Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589271017124100176Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589271017146851125Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590173096124173175Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590413140124413285Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590413140124413285Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592682300126682419Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595085348129085464Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595286714129286920Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595317683129317856Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595317683129317856Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595317683129317856Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596172519130172667Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined596883692130883925Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined596883692130883925Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined597871790116738565Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99801563126805880Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100527900134527900Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100527900134527900Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101194514135194514Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101725767135725963Mouse
14746986Manh58_mmandible shape 58 (mouse)5102308218136308218Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102806972136807131Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5102900000115400000Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104239005120573921Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104350872114963481Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104435822138557193Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104567876138567876Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107829235141829348Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107829235141829348Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107829235141829348Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108614643126805880Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109090176143090317Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109090176143090317Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109090758139133150Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109362284143362395Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110105240117955608Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113172519138557193Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5113883692129555542Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1539
Count of miRNA genes:463
Interacting mature miRNAs:538
Transcripts:ENSMUST00000071968, ENSMUST00000112217, ENSMUST00000112219, ENSMUST00000112222, ENSMUST00000112225, ENSMUST00000133019, ENSMUST00000141828
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071968   ⟹   ENSMUSP00000071859
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,213 - 114,796,482 (-)Ensembl
GRCm38.p6 Ensembl5114,622,152 - 114,658,421 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112217   ⟹   ENSMUSP00000107836
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,714 - 114,782,960 (-)Ensembl
GRCm38.p6 Ensembl5114,622,653 - 114,644,899 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112219   ⟹   ENSMUSP00000107838
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,714 - 114,782,960 (-)Ensembl
GRCm38.p6 Ensembl5114,622,653 - 114,644,899 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112222   ⟹   ENSMUSP00000107840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,714 - 114,782,960 (-)Ensembl
GRCm38.p6 Ensembl5114,622,653 - 114,644,899 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112225   ⟹   ENSMUSP00000107844
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,215 - 114,796,479 (-)Ensembl
GRCm38.p6 Ensembl5114,622,154 - 114,658,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133019
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,760,218 - 114,774,322 (-)Ensembl
GRCm38.p6 Ensembl5114,622,157 - 114,636,261 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141828
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,764,805 - 114,768,699 (-)Ensembl
GRCm38.p6 Ensembl5114,626,744 - 114,630,638 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212469
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,774,193 - 114,782,960 (-)Ensembl
GRCm38.p6 Ensembl5114,636,132 - 114,644,899 (-)Ensembl
RefSeq Acc Id: NM_022017   ⟹   NP_071300
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,760,215 - 114,796,482 (-)NCBI
GRCm385114,622,154 - 114,658,421 (-)NCBI
MGSCv375115,072,163 - 115,108,430 (-)RGD
Celera5111,719,696 - 111,755,858 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530432   ⟹   XP_006530495
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,760,213 - 114,796,496 (-)NCBI
GRCm385114,622,152 - 114,658,435 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248235   ⟹   XP_011246537
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,763,121 - 114,796,496 (-)NCBI
GRCm385114,625,060 - 114,658,435 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165405   ⟹   XP_036021298
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,766,875 - 114,796,497 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_071300   ⟸   NM_022017
- UniProtKB: Q9EPK8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006530495   ⟸   XM_006530432
- Peptide Label: isoform X1
- UniProtKB: Q9EPK8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011246537   ⟸   XM_011248235
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000071859   ⟸   ENSMUST00000071968
RefSeq Acc Id: ENSMUSP00000107838   ⟸   ENSMUST00000112219
RefSeq Acc Id: ENSMUSP00000107836   ⟸   ENSMUST00000112217
RefSeq Acc Id: ENSMUSP00000107840   ⟸   ENSMUST00000112222
RefSeq Acc Id: ENSMUSP00000107844   ⟸   ENSMUST00000112225
RefSeq Acc Id: XP_036021298   ⟸   XM_036165405
- Peptide Label: isoform X3
Protein Domains
Ion_trans

Promoters
RGD ID:6887684
Promoter ID:EPDNEW_M7293
Type:initiation region
Name:Trpv4_1
Description:Mus musculus transient receptor potential cation channel, subfamilyV, member 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385114,658,373 - 114,658,433EPDNEW
RGD ID:6838550
Promoter ID:MM_KWN:43558
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000034429
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,080,321 - 115,080,821 (-)MPROMDB
RGD ID:6838552
Promoter ID:MM_KWN:43559
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:UC008YZU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,085,771 - 115,086,322 (-)MPROMDB
RGD ID:6838548
Promoter ID:MM_KWN:43560
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000112217,   ENSMUST00000112219,   ENSMUST00000112222
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,095,171 - 115,095,671 (-)MPROMDB
RGD ID:6838551
Promoter ID:MM_KWN:43561
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000112225,   OTTMUST00000034430
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365115,107,921 - 115,108,421 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1926945 AgrOrtholog
Ensembl Genes ENSMUSG00000014158 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000071859 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000107836 UniProtKB/TrEMBL
  ENSMUSP00000107838 UniProtKB/TrEMBL
  ENSMUSP00000107840 UniProtKB/TrEMBL
  ENSMUSP00000107844 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000071968 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000112217 UniProtKB/TrEMBL
  ENSMUST00000112219 UniProtKB/TrEMBL
  ENSMUST00000112222 UniProtKB/TrEMBL
  ENSMUST00000112225 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV1-4_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRPV4_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:63873 UniProtKB/Swiss-Prot
MGD MGI:1926945 ENTREZGENE
NCBI Gene 63873 ENTREZGENE
PANTHER PTHR10582 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10582:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ank UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trpv4 PhenoGen
PRINTS TRPVRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VRL2RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z1H6_MOUSE UniProtKB/TrEMBL
  D3Z1H7_MOUSE UniProtKB/TrEMBL
  E9Q7L7_MOUSE UniProtKB/TrEMBL
  Q3TYG5_MOUSE UniProtKB/TrEMBL
  Q9EPK8 ENTREZGENE, UniProtKB/Swiss-Prot
  V9SH16_MOUSE UniProtKB/TrEMBL
UniProt Secondary A0JNY0 UniProtKB/Swiss-Prot
  Q91XR5 UniProtKB/Swiss-Prot
  Q9EQZ4 UniProtKB/Swiss-Prot
  Q9ERZ7 UniProtKB/Swiss-Prot
  Q9ES76 UniProtKB/Swiss-Prot