Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of YKT6 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of YKT6 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of YKT6 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of YKT6 mRNA | CTD | PMID:15034205 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of YKT6 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of YKT6 mRNA | CTD | PMID:30047161 | acrylamide | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of YKT6 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | decreases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of YKT6 mRNA | CTD | PMID:15498508 | amitrole | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of YKT6 mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of YKT6 mRNA | CTD | PMID:16483693 | aristolochic acid A | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of YKT6 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic affects the methylation of YKT6 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic affects the methylation of YKT6 gene | CTD | PMID:25304211 | arsenous acid | decreases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of YKT6 protein | CTD | PMID:25419056 | arsenous acid | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to YKT6 protein] | CTD | PMID:26598702 | beauvericin | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein | CTD | PMID:32407736 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of YKT6 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of YKT6 mRNA | CTD | PMID:15034205 | bisphenol A | decreases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of YKT6 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of YKT6 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | multiple interactions | ISO | Ykt6 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of YKT6 gene | CTD | PMID:28505145 | Bisphenol B | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of YKT6 protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of YKT6 protein | CTD | PMID:34186270 | captan | increases expression | EXP | | 6480464 | Captan results in increased expression of YKT6 mRNA | CTD | PMID:31558096 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of YKT6 mRNA | CTD | PMID:25554681 | chlordecone | multiple interactions | EXP | | 6480464 | Chlordecone promotes the reaction [Biomarkers metabolite binds to YKT6 gene] | CTD | PMID:31084621 | cobalt dichloride | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of YKT6 mRNA | CTD | PMID:19376846 | copper(II) sulfate | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of YKT6 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of YKT6 mRNA | CTD | PMID:20106945 and PMID:25562108 | diarsenic trioxide | decreases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of YKT6 protein | CTD | PMID:25419056 | diarsenic trioxide | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to YKT6 protein] | CTD | PMID:26598702 | dorsomorphin | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of YKT6 mRNA | CTD | PMID:27188386 | enniatin | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | [beauvericin co-treated with enniatins] results in increased expression of YKT6 protein | CTD | PMID:32407736 | ethanol | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Ethanol results in increased expression of YKT6 mRNA | CTD | PMID:20655511 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of YKT6 mRNA | CTD | PMID:34813904 | flavonoids | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Flavonoids results in increased expression of YKT6 mRNA | CTD | PMID:18035473 | flutamide | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of YKT6 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of YKT6 mRNA | CTD | PMID:22206623 | folpet | increases expression | EXP | | 6480464 | folpet results in increased expression of YKT6 mRNA | CTD | PMID:31558096 | FR900359 | increases phosphorylation | ISO | YKT6 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of YKT6 protein | CTD | PMID:37730182 | furan | increases methylation | ISO | Ykt6 (Rattus norvegicus) | 6480464 | furan results in increased methylation of YKT6 gene | CTD | PMID:22079235 | genistein | multiple interactions | ISO | Ykt6 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Genistein] results in increased methylation of YKT6 gene | CTD | PMID:28505145 | gentamycin | decreases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of YKT6 mRNA | CTD | PMID:33387578 | glafenine | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Glafenine results in increased expression of YKT6 mRNA | CTD | PMID:24136188 | ivermectin | decreases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of YKT6 protein | CTD | PMID:32959892 | menadione | affects expression | ISO | YKT6 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of YKT6 mRNA | CTD | PMID:20044591 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of YKT6 mRNA | CTD | PMID:34813904 | methimazole | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of YKT6 mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of YKT6 mRNA | CTD | PMID:28001369 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of YKT6 protein | CTD | PMID:26558463 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of YKT6 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of YKT6 mRNA | CTD | PMID:22230336 and PMID:29067470 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of YKT6 mRNA | CTD | PMID:23892564 | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of YKT6 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of YKT6 protein | CTD | PMID:26178269 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of YKT6 mRNA | CTD | PMID:36331819 | phenylmercury acetate | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of YKT6 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of YKT6 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of YKT6 mRNA | CTD | PMID:23811191 | rotenone | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Rotenone results in increased expression of YKT6 mRNA | CTD | PMID:33512557 | rotenone | decreases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of YKT6 protein | CTD | PMID:35544339 | SB 431542 | multiple interactions | ISO | YKT6 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of YKT6 mRNA | CTD | PMID:27188386 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of YKT6 protein | CTD | PMID:28918527 | sulfadimethoxine | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of YKT6 mRNA | CTD | PMID:30047161 | tamibarotene | affects expression | ISO | YKT6 (Homo sapiens) | 6480464 | tamibarotene affects the expression of YKT6 mRNA | CTD | PMID:15498508 | testosterone enanthate | affects expression | ISO | YKT6 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of YKT6 mRNA | CTD | PMID:17440010 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of YKT6 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of YKT6 mRNA | CTD | PMID:33387578 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of YKT6 mRNA | CTD | PMID:27760801 | toluene | increases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Toluene results in increased expression of YKT6 mRNA | CTD | PMID:22166486 | toluene | decreases expression | ISO | Ykt6 (Rattus norvegicus) | 6480464 | Toluene results in decreased expression of YKT6 mRNA | CTD | PMID:22166486 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of YKT6 mRNA | CTD | PMID:19042947 | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of YKT6 mRNA | CTD | PMID:28973697 | trovafloxacin | increases expression | EXP | | 6480464 | trovafloxacin results in increased expression of YKT6 mRNA | CTD | PMID:35537566 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of YKT6 mRNA | CTD | PMID:17292431 | valproic acid | affects expression | ISO | YKT6 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of YKT6 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | YKT6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of YKT6 mRNA | CTD | PMID:23179753 and PMID:28001369 | zearalenone | multiple interactions | EXP | | 6480464 | [Zearalenone co-treated with CGA protein] results in increased expression of YKT6 protein | CTD | PMID:25058043 | |