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Gene: FGF1 (fibroblast growth factor 1) Homo sapiens
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Symbol: FGF1
Name: fibroblast growth factor 1
Description: Exhibits S100 protein binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including activation of protein kinase activity; positive regulation of biosynthetic process; and regulation of endothelial cell migration. Localizes to the cytosol; extracellular space; and nucleoplasm. Implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Biomarker of Alzheimer's disease; endometrial cancer; leiomyoma; ovarian cancer; and transitional cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acidic fibroblast growth factor; AFGF; beta-endothelial cell growth factor; ECGF; ECGF-beta; ECGFA; ECGFB; endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF-1; FGF-alpha; FGFA; fibroblast growth factor 1 (acidic); GLIO703; HBGF-1; HBGF1; heparin-binding growth factor 1
Orthologs:
Mus musculus (house mouse) : Fgf1 (fibroblast growth factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgf1 (fibroblast growth factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf1 (fibroblast growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF1 (fibroblast growth factor 1)
Canis lupus familiaris (dog) : FGF1 (fibroblast growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf1 (fibroblast growth factor 1)
Sus scrofa (pig) : FGF1 (fibroblast growth factor 1)
Chlorocebus sabaeus (green monkey) : FGF1 (fibroblast growth factor 1)
Heterocephalus glaber (naked mole-rat) : Fgf1 (fibroblast growth factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl5142,592,178 - 142,698,070 (-)Ensembl
GRCh385142,592,178 - 142,698,070 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375141,971,743 - 142,077,635 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365141,953,306 - 142,045,812 (-)NCBINCBI36hg18NCBI36
Build 345141,953,306 - 142,045,812NCBI
Celera5138,053,068 - 138,158,948 (-)NCBI
Cytogenetic Map5q31.3NCBI
HuRef5137,119,474 - 137,224,982 (-)NCBIHuRef
CHM1_15141,405,414 - 141,511,305 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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