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Gene: Zic1 (zinc finger protein of the cerebellum 1) Mus musculus
Symbol: Zic1
Name: zinc finger protein of the cerebellum 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including adult walking behavior; central nervous system development; and positive regulation of protein import into nucleus. Localizes to the cytoplasm and nucleus. Used to study Dandy-Walker syndrome and Joubert syndrome. Human ortholog(s) of this gene implicated in Dandy-Walker syndrome and craniosynostosis. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; future brain; and metanephros. Orthologous to human ZIC1 (Zic family member 1); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: odd-paired homolog; ZIC; Zic family member 1 (odd-paired homolog, Drosophila); zinc finger protein ZIC 1; ZNF201
Homo sapiens (human) : ZIC1 (Zic family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Zic1 (Zic family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic1 (Zic family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC1 (Zic family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic1 (Zic family member 1)
Sus scrofa (pig) : ZIC1 (Zic family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38991,358,058 - 91,366,247 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37991,255,183 - 91,260,637 (-)NCBIGRCm37mm9NCBIm37
MGSCv36991,158,250 - 91,163,704 (-)NCBImm8
Celera990,951,458 - 90,958,970 (-)NCBICelera
Cytogenetic Map9 E3.2NCBI
cM Map948.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Zic1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735695
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.