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Gene: Zic1 (zinc finger protein of the cerebellum 1) Mus musculus
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Symbol: Zic1
Name: zinc finger protein of the cerebellum 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including adult walking behavior; central nervous system development; and positive regulation of protein import into nucleus. Localizes to the cytoplasm and nucleus. Used to study Dandy-Walker syndrome and Joubert syndrome. Human ortholog(s) of this gene implicated in Dandy-Walker syndrome and craniosynostosis. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; future brain; and metanephros. Orthologous to human ZIC1 (Zic family member 1); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: odd-paired homolog; ZIC; Zic family member 1 (odd-paired homolog, Drosophila); zinc finger protein ZIC 1; ZNF201
Orthologs:
Homo sapiens (human) : ZIC1 (Zic family member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Zic1 (Zic family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic1 (Zic family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC1 (Zic family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic1 (Zic family member 1)
Sus scrofa (pig) : ZIC1 (Zic family member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38991,358,058 - 91,366,247 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37991,255,183 - 91,260,637 (-)NCBIGRCm37mm9NCBIm37
MGSCv36991,158,250 - 91,163,704 (-)NCBImm8
Celera990,951,458 - 90,958,970 (-)NCBICelera
Cytogenetic Map9 E3.2NCBI
cM Map948.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Zic1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735695
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.