Galr1 (galanin receptor 1) - Rat Genome Database

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Gene: Galr1 (galanin receptor 1) Mus musculus
Analyze
Symbol: Galr1
Name: galanin receptor 1
RGD ID: 735655
MGI Page MGI
Description: Predicted to enable galanin receptor activity; neuropeptide binding activity; and peptide hormone binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; positive regulation of cortisol secretion; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within signal transduction. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in adrenal gland; alimentary system; male reproductive gland or organ; and nervous system. Orthologous to human GALR1 (galanin receptor 1); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ga; GAL1-R; galanin receptor type 1; Galnr1; GALR-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391882,410,621 - 82,424,902 (-)NCBIGRCm39mm39
GRCm39 Ensembl1882,410,505 - 82,424,902 (-)Ensembl
GRCm381882,392,496 - 82,406,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1882,392,380 - 82,406,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv371882,561,888 - 82,576,169 (-)NCBIGRCm37mm9NCBIm37
MGSCv361882,527,838 - 82,541,229 (-)NCBImm8
Celera1883,464,283 - 83,478,564 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1855.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:9271210   PMID:9337411   PMID:9367674   PMID:9832121   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11145992   PMID:11217851   PMID:12466851   PMID:12477932  
PMID:12487125   PMID:12533601   PMID:12605897   PMID:12605908   PMID:12700679   PMID:12842279   PMID:12887433   PMID:15016096   PMID:15240875   PMID:15249737   PMID:15281082   PMID:15350653  
PMID:15365683   PMID:15748163   PMID:15885916   PMID:15934937   PMID:15944013   PMID:15944015   PMID:15944016   PMID:15944033   PMID:16141072   PMID:16141073   PMID:16243364   PMID:16602821  
PMID:16987237   PMID:16998907   PMID:17223141   PMID:17439488   PMID:17543594   PMID:17627995   PMID:17974627   PMID:18363852   PMID:19127771   PMID:19272414   PMID:20197068   PMID:21150899  
PMID:21179451   PMID:21267068   PMID:21873635   PMID:21969124   PMID:22723691   PMID:23387435   PMID:23639882   PMID:24726665   PMID:24952961   PMID:25082697   PMID:25690510   PMID:26292267  
PMID:26324777   PMID:26661062   PMID:27223629   PMID:27568567   PMID:28413018   PMID:31953035  


Genomics

Comparative Map Data
Galr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391882,410,621 - 82,424,902 (-)NCBIGRCm39mm39
GRCm39 Ensembl1882,410,505 - 82,424,902 (-)Ensembl
GRCm381882,392,496 - 82,406,777 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1882,392,380 - 82,406,777 (-)EnsemblGRCm38mm10GRCm38
MGSCv371882,561,888 - 82,576,169 (-)NCBIGRCm37mm9NCBIm37
MGSCv361882,527,838 - 82,541,229 (-)NCBImm8
Celera1883,464,283 - 83,478,564 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1855.78NCBI
GALR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1877,249,848 - 77,277,900 (+)EnsemblGRCh38hg38GRCh38
GRCh381877,249,848 - 77,277,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371874,961,804 - 74,989,856 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361873,090,721 - 73,111,081 (+)NCBINCBI36hg18NCBI36
Build 341873,090,720 - 73,111,081NCBI
Celera1871,781,397 - 71,801,439 (+)NCBI
Cytogenetic Map18q23NCBI
HuRef1871,642,787 - 71,663,380 (+)NCBIHuRef
CHM1_11874,958,364 - 74,978,152 (+)NCBICHM1_1
Galr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21875,772,021 - 75,787,577 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1875,772,023 - 75,787,577 (-)Ensembl
Rnor_6.01879,243,009 - 79,258,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1879,243,009 - 79,258,570 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01878,302,017 - 78,317,578 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41878,858,892 - 78,874,451 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11878,941,425 - 78,947,496 (-)NCBI
Celera1874,409,272 - 74,424,831 (-)NCBICelera
RH 3.4 Map18809.9RGD
Cytogenetic Map18q12.3NCBI
Galr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540260,546,186 - 60,559,298 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540260,449,660 - 60,559,549 (+)NCBIChiLan1.0ChiLan1.0
GALR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11873,899,995 - 73,917,849 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1873,899,995 - 73,917,752 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01870,643,718 - 70,664,068 (+)NCBIMhudiblu_PPA_v0panPan3
GALR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112,750,117 - 2,785,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12,729,331 - 2,742,231 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12,729,331 - 2,742,231 (-)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha13,728,748 - 3,802,391 (-)NCBI
ROS_Cfam_1.012,528,062 - 2,601,762 (-)NCBI
UMICH_Zoey_3.112,573,436 - 2,647,073 (-)NCBI
UNSW_CanFamBas_1.012,523,851 - 2,597,515 (-)NCBI
UU_Cfam_GSD_1.012,694,052 - 2,767,702 (-)NCBI
Galr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494416,679,669 - 16,700,474 (-)NCBI
SpeTri2.0NW_0049366162,007,339 - 2,020,737 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GALR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,443,821 - 147,463,542 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11147,442,977 - 147,466,731 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21162,977,166 - 162,994,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GALR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1182,719,736 - 2,739,018 (-)NCBI
Vero_WHO_p1.0NW_02366606023,243,960 - 23,263,451 (+)NCBI
Galr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248063,331,025 - 3,347,774 (-)NCBI

Position Markers
Galr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381882,393,695 - 82,393,786UniSTSGRCm38
MGSCv371882,563,087 - 82,563,178UniSTSGRCm37
Celera1883,465,482 - 83,465,573UniSTS
Cytogenetic Map18E3-E4UniSTS
cM Map1855.0UniSTS
RH94734  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381882,393,788 - 82,393,912UniSTSGRCm38
MGSCv371882,563,180 - 82,563,304UniSTSGRCm37
Celera1883,465,575 - 83,465,699UniSTS
Cytogenetic Map18E3-E4UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357639Obsty4_mobesity 4 (mouse)Not determined183948686184620653Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185091908584919240Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185091908584919240Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185153522985535397Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185153522985535397Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185267220586672345Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185484280185496018Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185630000090300000Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185630000090300000Mouse
12880428V125Dq14_mvitamin D active form serum level QTL 14 (mouse)185730000090702639Mouse
1301353Lbw6_mlupus NZB x NZW 6 (mouse)Not determined185742926790702639Mouse
4141132Eae18_mexperimental allergic encephalomyelitis susceptibility 18 (mouse)Not determined5745748782586603Mouse
4140971Mbmq1_mmale body mass QTL 1 (mouse)Not determined5785721090702639Mouse
11039492Ltpr8a_mLeishmania tropica response 8a (mouse)185904702190702639Mouse
11039495Ltpr8c_mLeishmania tropica response 8c (mouse)185904702190702639Mouse
11049564Lmr29_mleishmaniasis resistance 29 (mouse)185904702190702639Mouse
1301103Pgia11_mproteoglycan induced arthritis 11 (mouse)Not determined185982648990702639Mouse
1302109Sluc28_msusceptibility to lung cancer 28 (mouse)Not determined185984762690702639Mouse
1558782Orgwq9_morgan weight QTL 9 (mouse)Not determined186113937682586603Mouse
1301798Hdlq31_mHDL QTL 31 (mouse)Not determined186712626490702639Mouse
10401904Sicd4_mseizure-induced cell death 4 (mouse)Not determined186967220585496018Mouse
15014786Mvlq2_mmacrovesicular liver lesion QTL 2 (mouse)187155126490702639Mouse
1302183Pas7_mpulmonary adenoma susceptibility 7 (mouse)Not determined187261252384126470Mouse
4142153Idd21.1_minsulin dependent diabetes susceptibility 21.1 (mouse)Not determined187442926784126470Mouse
4141757Sicd1_mseizure-induced cell death 1 (mouse)Not determined188013204989572790Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:372
Count of miRNA genes:256
Interacting mature miRNAs:303
Transcripts:ENSMUST00000065224
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000065224   ⟹   ENSMUSP00000066381
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1882,410,505 - 82,424,902 (-)Ensembl
GRCm38.p6 Ensembl1882,392,380 - 82,406,777 (-)Ensembl
RefSeq Acc Id: NM_008082   ⟹   NP_032108
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391882,410,621 - 82,424,902 (-)NCBI
GRCm381882,392,496 - 82,406,777 (-)ENTREZGENE
MGSCv371882,561,888 - 82,576,169 (-)RGD
Celera1883,464,283 - 83,478,564 (-)RGD
cM Map18 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032108 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB87748 (Get FASTA)   NCBI Sequence Viewer  
  CAA75237 (Get FASTA)   NCBI Sequence Viewer  
  EDL09388 (Get FASTA)   NCBI Sequence Viewer  
  EDL09389 (Get FASTA)   NCBI Sequence Viewer  
  P56479 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_032108   ⟸   NM_008082
- UniProtKB: P56479 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000066381   ⟸   ENSMUST00000065224

Promoters
RGD ID:6829239
Promoter ID:MM_KWN:25837
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_008082
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361882,575,001 - 82,575,501 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1096364 AgrOrtholog
Ensembl Genes ENSMUSG00000024553 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000066381 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000065224 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro GAL1_rcpt UniProtKB/Swiss-Prot
  Galanin_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report mmu:14427 UniProtKB/Swiss-Prot
MGD MGI:1096364 ENTREZGENE
NCBI Gene 14427 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Galr1 PhenoGen
PRINTS GALANIN1R UniProtKB/Swiss-Prot
  GALANINR UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
UniProt GALR1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE