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Gene: Pfkfb3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3) Mus musculus
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Symbol: Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Description: Predicted to have 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to localize to the cytosol and nucleoplasm. Used to study extrinsic cardiomyopathy. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and skeleton. Orthologous to human PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3); PARTICIPATES IN glycolysis pathway; hypoxia inducible factor pathway; fructose and mannose metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; E330010H22Rik; inducible 6-phosphofructo-2-kinase; iPFK-2; uPFK-2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl211,471,433 - 11,554,077 (-)Ensembl
GRCm38211,471,430 - 11,554,071 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37211,393,057 - 11,475,556 (-)NCBIGRCm37mm9NCBIm37
MGSCv36211,389,288 - 11,419,920 (-)NCBImm8
Celera211,389,848 - 11,473,089 (-)NCBICelera
Cytogenetic Map2 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pfkfb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735561
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.