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Gene: Foxe1 (forkhead box E1) Mus musculus
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Symbol: Foxe1
Name: forkhead box E1
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including animal organ development; roof of mouth development; and thyroid hormone generation. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; brain; branchial pouch endoderm; head surface ectoderm; and outflow tract. Used to study Bamforth-Lazarus syndrome and congenital hypothyroidism. Human ortholog(s) of this gene implicated in Bamforth-Lazarus syndrome and thyroid gland papillary carcinoma. Orthologous to human FOXE1 (forkhead box E1); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: forkhead box protein E1; thyroid transcription factor 2; Titf2; TTF-2
Orthologs:
Homo sapiens (human) : FOXE1 (forkhead box E1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxe1 (forkhead box E1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxe1 (forkhead box E1)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXE1 (forkhead box E1)
Canis lupus familiaris (dog) : FOXE1 (forkhead box E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxe1 (forkhead box E1)
Sus scrofa (pig) : FOXE1 (forkhead box E1)
Chlorocebus sabaeus (African green monkey) : FOXE1 (forkhead box E1)
Heterocephalus glaber (naked mole-rat) : Foxe1 (forkhead box E1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl446,343,609 - 46,346,412 (+)EnsemblGRCm38mm10GRCm38
GRCm38446,343,644 - 46,345,774 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37446,357,066 - 46,358,181 (+)NCBIGRCm37mm9NCBIm37
MGSCv36446,365,294 - 46,366,409 (+)NCBImm8
Celera446,367,115 - 46,367,868 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Foxe1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735500
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.