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Gene: Foxe1 (forkhead box E1) Mus musculus
Symbol: Foxe1
Name: forkhead box E1
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including animal organ development; roof of mouth development; and thyroid hormone generation. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; brain; branchial pouch endoderm; head surface ectoderm; and outflow tract. Used to study Bamforth-Lazarus syndrome and congenital hypothyroidism. Human ortholog(s) of this gene implicated in Bamforth-Lazarus syndrome and thyroid gland papillary carcinoma. Orthologous to human FOXE1 (forkhead box E1); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: forkhead box protein E1; thyroid transcription factor 2; Titf2; TTF-2
Homo sapiens (human) : FOXE1 (forkhead box E1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxe1 (forkhead box E1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxe1 (forkhead box E1)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXE1 (forkhead box E1)
Canis lupus familiaris (dog) : FOXE1 (forkhead box E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxe1 (forkhead box E1)
Sus scrofa (pig) : FOXE1 (forkhead box E1)
Chlorocebus sabaeus (African green monkey) : FOXE1 (forkhead box E1)
Heterocephalus glaber (naked mole-rat) : Foxe1 (forkhead box E1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl446,343,609 - 46,346,412 (+)EnsemblGRCm38mm10GRCm38
GRCm38446,343,644 - 46,345,774 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37446,357,066 - 46,358,181 (+)NCBIGRCm37mm9NCBIm37
MGSCv36446,365,294 - 46,366,409 (+)NCBImm8
Celera446,367,115 - 46,367,868 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Foxe1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735500
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.