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Gene: Clcn5 (chloride channel, voltage-sensitive 5) Mus musculus
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Symbol: Clcn5
Name: chloride channel, voltage-sensitive 5
Description: Predicted to have chloride ion binding activity; identical protein binding activity; and ion transmembrane transporter activity. Involved in endocytosis. Localizes to apical part of cell and endosome. Is expressed in heart and metanephros. Used to study Dent disease. Human ortholog(s) of this gene implicated in Dent disease; X-linked nephrolithiasis type I; X-linked recessive hypophosphatemic rickets; and low molecular weight proteinuria with hypercalciuric nephrocalcinosis. Orthologous to human CLCN5 (chloride voltage-gated channel 5); INTERACTS WITH 1,2-dimethylhydrazine; 1,4-dichlorobenzene; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430408K11Rik; chloride channel 4-1; chloride channel 5; chloride channel protein 5; chloride transporter ClC-5; ClC-5; Clc4-1; Clc5; Clcn4-1; D930009B12Rik; DXImx42e; H(+)/Cl(-) exchange transporter 5; Sfc13; T25545
Orthologs:
Homo sapiens (human) : CLCN5 (chloride voltage-gated channel 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clcn5 (chloride voltage-gated channel 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn5 (chloride voltage-gated channel 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN5 (chloride voltage-gated channel 5)
Canis lupus familiaris (dog) : CLCN5 (chloride voltage-gated channel 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn5 (chloride voltage-gated channel 5)
Sus scrofa (pig) : CLCN5 (chloride voltage-gated channel 5)
Chlorocebus sabaeus (African green monkey) : CLCN5 (chloride voltage-gated channel 5)
Heterocephalus glaber (naked mole-rat) : Clcn5 (chloride voltage-gated channel 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX7,153,810 - 7,319,358 (-)EnsemblGRCm38mm10GRCm38
GRCm38X7,153,810 - 7,319,358 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X6,735,945 - 6,765,840 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X6,316,432 - 6,345,645 (-)NCBImm8
CeleraX4,285,826 - 4,305,500 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Clcn5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735491
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.