VAMP2 (vesicle associated membrane protein 2) - Rat Genome Database

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Gene: VAMP2 (vesicle associated membrane protein 2) Homo sapiens
Analyze
Symbol: VAMP2
Name: vesicle associated membrane protein 2
RGD ID: 735448
HGNC Page HGNC:12643
Description: Enables syntaxin binding activity. Involved in eosinophil degranulation and vesicle fusion. Located in clathrin-coated vesicle and membrane. Part of SNARE complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: FLJ11460; NEDHAHM; SYB2; synaptobrevin 2; synaptobrevin-2; VAMP-2; vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,159,147 - 8,162,948 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,159,149 - 8,163,546 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,062,465 - 8,066,266 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,003,189 - 8,007,017 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,003,188 - 8,007,017NCBI
Celera178,089,806 - 8,093,640 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,957,475 - 7,960,724 (-)NCBIHuRef
CHM1_1178,071,269 - 8,075,097 (-)NCBICHM1_1
T2T-CHM13v2.0178,064,587 - 8,068,400 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
ammonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
buta-1,3-diene  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
capsaicin  (ISO)
carbon nanotube  (ISO)
cisplatin  (EXP)
clozapine  (ISO)
cobalt dichloride  (EXP)
D-gluconic acid  (ISO)
decabromodiphenyl ether  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
ethanol  (ISO)
FR900359  (EXP)
fulvestrant  (EXP)
gamma-tocopherol  (ISO)
haloperidol  (ISO)
hydrazines  (ISO)
hypochlorous acid  (ISO)
ivermectin  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
leflunomide  (EXP)
methylparaben  (EXP)
nicotinamide  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (ISO)
propiconazole  (ISO)
resveratrol  (EXP,ISO)
SB 431542  (EXP)
streptozocin  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (ISO)
tocopherol  (ISO)
trichloroethene  (ISO)
trimethylamine N-oxide  (ISO)
urethane  (EXP)
vinclozolin  (ISO)
vincristine  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Boone M and Deen PM, Pflugers Arch. 2008 Sep;456(6):1005-24. Epub 2008 Apr 23.
2. The GLUT4 code. Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins. Wang Z and Thurmond DC, J Cell Sci. 2009 Apr 1;122(Pt 7):893-903.
7. Insulin action on glucose transporters through molecular switches, tracks and tethers. Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15.
Additional References at PubMed
PMID:1976629   PMID:7499863   PMID:7553862   PMID:7622514   PMID:7835332   PMID:7961655   PMID:8011337   PMID:8071310   PMID:8125298   PMID:8760387   PMID:8770861   PMID:8973549  
PMID:8999968   PMID:9030619   PMID:9341137   PMID:9396746   PMID:9657962   PMID:9658161   PMID:9817754   PMID:9920726   PMID:10036234   PMID:10099709   PMID:10100611   PMID:10194441  
PMID:10336434   PMID:10370136   PMID:10449403   PMID:10481273   PMID:10662545   PMID:10713150   PMID:10820264   PMID:10965122   PMID:11031247   PMID:11101518   PMID:11252894   PMID:11278762  
PMID:11295657   PMID:11524423   PMID:11786915   PMID:11832227   PMID:11842301   PMID:11994746   PMID:12093152   PMID:12130530   PMID:12181340   PMID:12200427   PMID:12417022   PMID:12477932  
PMID:12485399   PMID:12517971   PMID:12730201   PMID:12750892   PMID:12773094   PMID:12828989   PMID:12832401   PMID:12847087   PMID:12853575   PMID:12855681   PMID:14702039   PMID:15217342  
PMID:15327778   PMID:15610015   PMID:16195891   PMID:16677249   PMID:17001002   PMID:17196367   PMID:17207965   PMID:17255364   PMID:17313651   PMID:17331077   PMID:17356306   PMID:18042464  
PMID:18182011   PMID:18253931   PMID:18511417   PMID:18511418   PMID:18512733   PMID:18628682   PMID:19478182   PMID:19543288   PMID:19546860   PMID:19557857   PMID:19822142   PMID:20416077  
PMID:20471030   PMID:20676083   PMID:20798282   PMID:21565611   PMID:21808019   PMID:21873635   PMID:22118466   PMID:22144578   PMID:22172278   PMID:22375059   PMID:22645275   PMID:22890573  
PMID:22939629   PMID:22956769   PMID:23100443   PMID:23376485   PMID:23897890   PMID:24164654   PMID:24623722   PMID:24878716   PMID:25416956   PMID:25445064   PMID:25481410   PMID:26134228  
PMID:26186194   PMID:26344197   PMID:26412491   PMID:26496610   PMID:26617273   PMID:26635000   PMID:26638075   PMID:26639969   PMID:26794648   PMID:27247366   PMID:27345149   PMID:27458546  
PMID:27616736   PMID:27762274   PMID:27791468   PMID:27880917   PMID:28495859   PMID:28514442   PMID:29328362   PMID:29358308   PMID:29360461   PMID:29568061   PMID:29608598   PMID:29997244  
PMID:30194290   PMID:30217970   PMID:30582321   PMID:30639242   PMID:30721745   PMID:30929742   PMID:31110017   PMID:31638250   PMID:31686426   PMID:31732153   PMID:31871319   PMID:32194132  
PMID:32296183   PMID:32393512   PMID:32580088   PMID:32675412   PMID:32812023   PMID:32814053   PMID:33217562   PMID:33845483   PMID:33961781   PMID:34079125   PMID:34183050   PMID:34190041  
PMID:34432599   PMID:34709727   PMID:35068871   PMID:35271311   PMID:36215168   PMID:36380732   PMID:37380951   PMID:37898760   PMID:38117590  


Genomics

Comparative Map Data
VAMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,159,147 - 8,162,948 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,159,149 - 8,163,546 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,062,465 - 8,066,266 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,003,189 - 8,007,017 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,003,188 - 8,007,017NCBI
Celera178,089,806 - 8,093,640 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,957,475 - 7,960,724 (-)NCBIHuRef
CHM1_1178,071,269 - 8,075,097 (-)NCBICHM1_1
T2T-CHM13v2.0178,064,587 - 8,068,400 (-)NCBIT2T-CHM13v2.0
Vamp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,979,354 - 68,983,207 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,979,316 - 68,983,210 (+)EnsemblGRCm39 Ensembl
GRCm381169,088,528 - 69,092,381 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,088,490 - 69,092,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,902,030 - 68,905,883 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,904,723 - 68,908,576 (+)NCBIMGSCv36mm8
Celera1176,032,081 - 76,035,943 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.36NCBI
Vamp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,292,423 - 54,296,657 (+)NCBIGRCr8
mRatBN7.21053,793,581 - 53,797,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,793,923 - 53,797,809 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,455,722 - 58,459,585 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,944,320 - 57,948,183 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,452,495 - 53,456,350 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,675,171 - 55,679,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,675,575 - 55,679,450 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,418,231 - 55,422,465 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,848,264 - 55,852,132 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,861,886 - 55,865,753 (+)NCBI
Celera1052,959,486 - 52,963,354 (+)NCBICelera
Cytogenetic Map10q24NCBI
Vamp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,793,296 - 8,796,771 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,793,296 - 8,796,771 (+)NCBIChiLan1.0ChiLan1.0
VAMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,589,912 - 65,594,126 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,399,645 - 70,403,527 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,495,464 - 43,499,348 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11748,228,253 - 48,231,948 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1748,228,253 - 48,231,948 (+)Ensemblpanpan1.1panPan2
VAMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,975,372 - 32,977,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,111,535 - 33,114,048 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,078,395 - 33,080,876 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,077,052 - 33,080,884 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,045,188 - 33,047,701 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,000,996 - 33,003,510 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,180,938 - 33,183,450 (-)NCBIUU_Cfam_GSD_1.0
Vamp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,911,504 - 47,915,326 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,385,695 - 1,389,552 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,385,692 - 1,389,484 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VAMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,378,409 - 53,382,240 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,378,407 - 53,382,243 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,853,614 - 55,857,435 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VAMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,539,098 - 7,542,466 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605913,862,312 - 13,866,164 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vamp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,724,964 - 10,727,649 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,723,791 - 10,727,654 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in VAMP2
20 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17p13.1(chr17:6958978-8335684)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052457]|See cases [RCV000052457] Chr17:6958978..8335684 [GRCh38]
Chr17:6862297..8239002 [GRCh37]
Chr17:6803021..8179727 [NCBI36]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.1(chr17:7750804-10112969)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052460]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052460]|See cases [RCV000052460] Chr17:7750804..10112969 [GRCh38]
Chr17:7654122..10016286 [GRCh37]
Chr17:7594847..9957011 [NCBI36]
Chr17:17p13.1		 pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:6307904-8842949)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053407]|See cases [RCV000053407] Chr17:6307904..8842949 [GRCh38]
Chr17:6211224..8746266 [GRCh37]
Chr17:6151948..8686991 [NCBI36]
Chr17:17p13.2-13.1		 pathogenic
GRCh38/hg38 17p13.1(chr17:7478195-8435524)x1 copy number loss See cases [RCV000053426] Chr17:7478195..8435524 [GRCh38]
Chr17:7381514..8338842 [GRCh37]
Chr17:7322238..8279567 [NCBI36]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.197G>A (p.Arg66His) single nucleotide variant not provided [RCV003221560] Chr17:8161693 [GRCh38]
Chr17:8065011 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.2-12(chr17:5732953-12095349)x3 copy number gain See cases [RCV000134851] Chr17:5732953..12095349 [GRCh38]
Chr17:5636273..11998666 [GRCh37]
Chr17:5576997..11939391 [NCBI36]
Chr17:17p13.2-12		 pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3 copy number gain See cases [RCV000138531] Chr17:162016..12343901 [GRCh38]
Chr17:45835..12247218 [GRCh37]
Chr17:11807..12187943 [NCBI36]
Chr17:17p13.3-12		 pathogenic
GRCh38/hg38 17p13.1(chr17:7967712-8490279)x3 copy number gain See cases [RCV000141063] Chr17:7967712..8490279 [GRCh38]
Chr17:7871030..8393597 [GRCh37]
Chr17:7811755..8334322 [NCBI36]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3 copy number gain See cases [RCV000142236] Chr17:150732..14764202 [GRCh38]
Chr17:525..14667519 [GRCh37]
Chr17:525..14608244 [NCBI36]
Chr17:17p13.3-12		 pathogenic
NM_014232.3(VAMP2):c.217G>T (p.Gly73Trp) single nucleotide variant not provided [RCV001194648] Chr17:8161673 [GRCh38]
Chr17:8064991 [GRCh37]
Chr17:17p13.1		 likely pathogenic
NM_014232.3(VAMP2):c.167G>T (p.Arg56Leu) single nucleotide variant not provided [RCV001194650] Chr17:8161723 [GRCh38]
Chr17:8065041 [GRCh37]
Chr17:17p13.1		 likely pathogenic
NM_014232.3(VAMP2):c.337_341del (p.Tyr113fs) deletion not provided [RCV001194651] Chr17:8160865..8160869 [GRCh38]
Chr17:8064183..8064187 [GRCh37]
Chr17:17p13.1		 likely pathogenic
GRCh37/hg19 17p13.1(chr17:8020196-8157327)x3 copy number gain Breast ductal adenocarcinoma [RCV000207207] Chr17:8020196..8157327 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:8017865-8135384)x3 copy number gain Breast ductal adenocarcinoma [RCV000207039] Chr17:8017865..8135384 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7966164-8338622)x3 copy number gain See cases [RCV000447606] Chr17:7966164..8338622 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7241916-8692213)x1 copy number loss See cases [RCV000445992] Chr17:7241916..8692213 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7929776-9995862)x3 copy number gain See cases [RCV000447853] Chr17:7929776..9995862 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.1(chr17:7431013-9868179)x3 copy number gain See cases [RCV000511388] Chr17:7431013..9868179 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-12(chr17:525-15027737)x3 copy number gain See cases [RCV000511786] Chr17:525..15027737 [GRCh37]
Chr17:17p13.3-12		 pathogenic
NC_000017.11:g.(?_7669603)_(8382316_?)del deletion Diamond-Blackfan anemia [RCV000538057]|Dyskeratosis congenita [RCV001382188]|Li-Fraumeni syndrome [RCV003105948] Chr17:7669603..8382316 [GRCh38]
Chr17:7572921..8285634 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:6934163-8217978)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626431] Chr17:6934163..8217978 [GRCh37]
Chr17:17p13.1		 drug response
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-11186432)x3 copy number gain not provided [RCV000683866] Chr17:525..11186432 [GRCh37]
Chr17:17p13.3-12		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.1(chr17:8044101-8068763)x1 copy number loss not provided [RCV000739396] Chr17:8044101..8068763 [GRCh37]
Chr17:17p13.1		 benign
GRCh37/hg19 17p13.1(chr17:8044148-8076916)x1 copy number loss not provided [RCV000739397] Chr17:8044148..8076916 [GRCh37]
Chr17:17p13.1		 benign
GRCh37/hg19 17p13.1(chr17:8044148-8125042)x1 copy number loss not provided [RCV000739398] Chr17:8044148..8125042 [GRCh37]
Chr17:17p13.1		 benign
NC_000017.10:g.(?_6589506)_(8151374_?)dup duplication Common variable immunodeficiency [RCV001338841]|Dyskeratosis congenita [RCV001031775] Chr17:6589506..8151374 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.128_130del microsatellite Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV000999497]|Severe neurodevelopmental delay [RCV000824682] Chr17:8161760..8161762 [GRCh38]
Chr17:8065078..8065080 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3:c.128_130del AND NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA deletion NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND AUTISTIC FEATURES WITH OR WITHOUT HYPERKINETIC MOVEMENTS [RCV000999497]   pathogenic
NM_014232.3(VAMP2):c.132CAT[1] (p.Ile45del) microsatellite Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV000999498] Chr17:8161753..8161755 [GRCh38]
Chr17:8065071..8065073 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7676383-8350870)x3 copy number gain not provided [RCV000848522] Chr17:7676383..8350870 [GRCh37]
Chr17:17p13.1		 uncertain significance
NC_000017.11:g.(?_7669599)_(8382320_?)del deletion Li-Fraumeni syndrome [RCV000803922] Chr17:7669599..8382320 [GRCh38]
Chr17:7572917..8285638 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.230T>C (p.Phe77Ser) single nucleotide variant Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV000999496] Chr17:8161660 [GRCh38]
Chr17:8064978 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.166C>T (p.Arg56Ter) single nucleotide variant not provided [RCV001194647] Chr17:8161724 [GRCh38]
Chr17:8065042 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.223T>C (p.Ser75Pro) single nucleotide variant Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV000999494] Chr17:8161667 [GRCh38]
Chr17:8064985 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.233A>C (p.Glu78Ala) single nucleotide variant Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV000999495] Chr17:8161657 [GRCh38]
Chr17:8064975 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.1A>G (p.Met1Val) single nucleotide variant not provided [RCV001194649] Chr17:8162879 [GRCh38]
Chr17:8066197 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7937691-8247776)x3 copy number gain not provided [RCV001006868] Chr17:7937691..8247776 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.221C>T (p.Ala74Val) single nucleotide variant Inborn genetic diseases [RCV001265983]|Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV001310231] Chr17:8161669 [GRCh38]
Chr17:8064987 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.334+12G>C single nucleotide variant Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV002243461]|not provided [RCV001779713] Chr17:8161461 [GRCh38]
Chr17:8064779 [GRCh37]
Chr17:17p13.1		 benign
NM_014232.3(VAMP2):c.38C>T (p.Pro13Leu) single nucleotide variant not provided [RCV001767816] Chr17:8162334 [GRCh38]
Chr17:8065652 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7020054-8086290) copy number loss not specified [RCV002052585] Chr17:7020054..8086290 [GRCh37]
Chr17:17p13.1		 pathogenic
GRCh37/hg19 17p13.1(chr17:7241916-8692213) copy number loss not specified [RCV002052586] Chr17:7241916..8692213 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.124-1G>C single nucleotide variant not provided [RCV001946052] Chr17:8161767 [GRCh38]
Chr17:8065085 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7929776-9995862) copy number gain not specified [RCV002052588] Chr17:7929776..9995862 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7593552-8225803) copy number gain not specified [RCV002052587] Chr17:7593552..8225803 [GRCh37]
Chr17:17p13.1		 uncertain significance
NC_000017.10:g.(?_7571752)_(8135555_?)del deletion Li-Fraumeni syndrome [RCV003107874] Chr17:7571752..8135555 [GRCh37]
Chr17:17p13.1		 pathogenic|uncertain significance
NC_000017.10:g.(?_7120455)_(8151423_?)del deletion Li-Fraumeni syndrome [RCV003111420] Chr17:7120455..8151423 [GRCh37]
Chr17:17p13.1		 pathogenic
NC_000017.10:g.(?_7571752)_(8285628_?)del deletion Li-Fraumeni syndrome [RCV003111422] Chr17:7571752..8285628 [GRCh37]
Chr17:17p13.1		 pathogenic
NM_014232.3(VAMP2):c.60del (p.Ala21fs) deletion Neurodevelopmental disorder [RCV002277692] Chr17:8162312 [GRCh38]
Chr17:8065630 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.1(chr17:7381537-8068400)x3 copy number gain not provided [RCV002474996] Chr17:7381537..8068400 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.37C>T (p.Pro13Ser) single nucleotide variant Inborn genetic diseases [RCV002912410] Chr17:8162335 [GRCh38]
Chr17:8065653 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.124-3C>T single nucleotide variant Inborn genetic diseases [RCV002717417]|VAMP2-related condition [RCV003936644] Chr17:8161769 [GRCh38]
Chr17:8065087 [GRCh37]
Chr17:17p13.1		 likely benign
NM_014232.3(VAMP2):c.13G>A (p.Ala5Thr) single nucleotide variant Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements [RCV003139260] Chr17:8162359 [GRCh38]
Chr17:8065677 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh38/hg38 17p13.3-12(chr17:165730-11404096)x3 copy number gain Chromosome 17p13.3 duplication syndrome [RCV003327726] Chr17:165730..11404096 [GRCh38]
Chr17:17p13.3-12		 pathogenic
NM_014232.3(VAMP2):c.256C>T (p.Arg86Cys) single nucleotide variant not provided [RCV003332731] Chr17:8161634 [GRCh38]
Chr17:8064952 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.8C>T (p.Ala3Val) single nucleotide variant Inborn genetic diseases [RCV003385696] Chr17:8162364 [GRCh38]
Chr17:8065682 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.328A>C (p.Ile110Leu) single nucleotide variant not provided [RCV003456971] Chr17:8161479 [GRCh38]
Chr17:8064797 [GRCh37]
Chr17:17p13.1		 uncertain significance
Single allele duplication not provided [RCV003448671] Chr17:7709286..8297901 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.294C>T (p.Ile98=) single nucleotide variant not provided [RCV003428132] Chr17:8161513 [GRCh38]
Chr17:8064831 [GRCh37]
Chr17:17p13.1		 likely benign
NM_014232.3(VAMP2):c.200C>T (p.Ala67Val) single nucleotide variant not provided [RCV003413145] Chr17:8161690 [GRCh38]
Chr17:8065008 [GRCh37]
Chr17:17p13.1		 uncertain significance
GRCh37/hg19 17p13.3-11.2(chr17:525-21510992)x3 copy number gain not specified [RCV003987215] Chr17:525..21510992 [GRCh37]
Chr17:17p13.3-11.2		 pathogenic
NM_014232.3(VAMP2):c.65C>T (p.Pro22Leu) single nucleotide variant VAMP2-related condition [RCV003901588] Chr17:8162307 [GRCh38]
Chr17:8065625 [GRCh37]
Chr17:17p13.1		 uncertain significance
NM_014232.3(VAMP2):c.183G>A (p.Ser61=) single nucleotide variant VAMP2-related condition [RCV003926868] Chr17:8161707 [GRCh38]
Chr17:8065025 [GRCh37]
Chr17:17p13.1		 likely benign
NM_014232.3(VAMP2):c.309C>T (p.Cys103=) single nucleotide variant not provided [RCV003884194] Chr17:8161498 [GRCh38]
Chr17:8064816 [GRCh37]
Chr17:17p13.1		 likely benign
NM_014232.3(VAMP2):c.147C>T (p.Asn49=) single nucleotide variant VAMP2-related condition [RCV003971652] Chr17:8161743 [GRCh38]
Chr17:8065061 [GRCh37]
Chr17:17p13.1		 likely benign
NC_000017.10:g.(?_7123304)_(8193254_?)del deletion Very long chain acyl-CoA dehydrogenase deficiency [RCV003119081] Chr17:7123304..8193254 [GRCh37]
Chr17:17p13.1		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2714
Count of miRNA genes:978
Interacting mature miRNAs:1143
Transcripts:ENST00000316509, ENST00000404970, ENST00000481878, ENST00000488857
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH55329  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37178,063,791 - 8,063,891UniSTSGRCh37
Build 36178,004,516 - 8,004,616RGDNCBI36
Celera178,091,139 - 8,091,239RGD
Cytogenetic Map17p13.1UniSTS
HuRef177,958,813 - 7,958,913UniSTS
Whitehead-RH Map1763.7UniSTS
NCBI RH Map17151.6UniSTS
RH44899  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37178,065,605 - 8,065,796UniSTSGRCh37
Build 36178,006,330 - 8,006,521RGDNCBI36
Celera178,092,953 - 8,093,144RGD
Cytogenetic Map17p13.1UniSTS
HuRef177,960,627 - 7,960,818UniSTS
GeneMap99-GB4 RH Map1753.5UniSTS
WIAF-1699  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37178,062,561 - 8,062,724UniSTSGRCh37
Build 36178,003,286 - 8,003,449RGDNCBI36
Celera178,089,902 - 8,090,065RGD
Cytogenetic Map17p13.1UniSTS
HuRef177,957,571 - 7,957,734UniSTS
GeneMap99-GB4 RH Map1753.7UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 2
Medium 2428 2977 1700 599 1932 440 4352 2188 3730 414 1449 1611 174 1 1204 2787 5 2
Low 11 14 26 25 19 25 5 9 2 5 11 2 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000316509   ⟹   ENSP00000314214
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,159,149 - 8,162,948 (-)Ensembl
RefSeq Acc Id: ENST00000404970   ⟹   ENSP00000466995
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,160,406 - 8,163,546 (-)Ensembl
RefSeq Acc Id: ENST00000481878   ⟹   ENSP00000467399
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,161,319 - 8,162,948 (-)Ensembl
RefSeq Acc Id: ENST00000488857   ⟹   ENSP00000418572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,160,819 - 8,162,932 (-)Ensembl
RefSeq Acc Id: ENST00000711100   ⟹   ENSP00000518578
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl178,160,406 - 8,162,948 (-)Ensembl
RefSeq Acc Id: NM_001330125   ⟹   NP_001317054
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,159,147 - 8,162,876 (-)NCBI
T2T-CHM13v2.0178,064,587 - 8,068,328 (-)NCBI
Sequence:
RefSeq Acc Id: NM_014232   ⟹   NP_055047
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,159,149 - 8,162,948 (-)NCBI
GRCh37178,062,465 - 8,066,293 (-)ENTREZGENE
Build 36178,003,189 - 8,007,017 (-)NCBI Archive
HuRef177,957,475 - 7,960,724 (-)ENTREZGENE
CHM1_1178,071,269 - 8,075,097 (-)NCBI
T2T-CHM13v2.0178,064,589 - 8,068,400 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_055047   ⟸   NM_014232
- Peptide Label: isoform 1
- UniProtKB: P19065 (UniProtKB/Swiss-Prot),   Q9BUC2 (UniProtKB/Swiss-Prot),   P63027 (UniProtKB/Swiss-Prot),   J3QRU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001317054   ⟸   NM_001330125
- Peptide Label: isoform 2
- UniProtKB: F8WCA0 (UniProtKB/TrEMBL),   J3QRU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000467399   ⟸   ENST00000481878
RefSeq Acc Id: ENSP00000466995   ⟸   ENST00000404970
RefSeq Acc Id: ENSP00000314214   ⟸   ENST00000316509
RefSeq Acc Id: ENSP00000418572   ⟸   ENST00000488857
RefSeq Acc Id: ENSP00000518578   ⟸   ENST00000711100
Protein Domains
v-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63027-F1-model_v2 AlphaFold P63027 1-116 view protein structure

Promoters
RGD ID:6811385
Promoter ID:HG_ACW:33013
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:VAMP2ANDPER1.TAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 36177,998,171 - 7,998,671 (-)MPROMDB
RGD ID:6811384
Promoter ID:HG_ACW:33014
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:VAMP2ANDPER1.BAPR07,   VAMP2ANDPER1.MAPR07,   VAMP2ANDPER1.QAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 36178,000,266 - 8,000,942 (-)MPROMDB
RGD ID:6814632
Promoter ID:HG_XEF:3253
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:NM_001039486,   NM_001087474,   NM_200005,   NM_214630
Position:
Human AssemblyChrPosition (strand)Source
Build 36178,005,774 - 8,006,274 (-)MPROMDB
RGD ID:6794740
Promoter ID:HG_KWN:24945
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000316509,   ENST00000396305,   ENST00000396308,   OTTHUMT00000317119,   OTTHUMT00000317121,   OTTHUMT00000317122
Position:
Human AssemblyChrPosition (strand)Source
Build 36178,006,556 - 8,008,557 (-)MPROMDB
RGD ID:7233897
Promoter ID:EPDNEW_H22694
Type:initiation region
Name:VAMP2_5
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22695  EPDNEW_H22697  EPDNEW_H22696  EPDNEW_H22698  EPDNEW_H22699  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,159,330 - 8,159,390EPDNEW
RGD ID:7233899
Promoter ID:EPDNEW_H22695
Type:initiation region
Name:VAMP2_4
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22694  EPDNEW_H22697  EPDNEW_H22696  EPDNEW_H22698  EPDNEW_H22699  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,160,821 - 8,160,881EPDNEW
RGD ID:7233903
Promoter ID:EPDNEW_H22696
Type:initiation region
Name:VAMP2_7
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22694  EPDNEW_H22695  EPDNEW_H22697  EPDNEW_H22698  EPDNEW_H22699  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,160,954 - 8,161,014EPDNEW
RGD ID:7233901
Promoter ID:EPDNEW_H22697
Type:initiation region
Name:VAMP2_3
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22694  EPDNEW_H22695  EPDNEW_H22696  EPDNEW_H22698  EPDNEW_H22699  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,161,471 - 8,161,531EPDNEW
RGD ID:7233905
Promoter ID:EPDNEW_H22698
Type:initiation region
Name:VAMP2_6
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22694  EPDNEW_H22695  EPDNEW_H22697  EPDNEW_H22696  EPDNEW_H22699  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,162,322 - 8,162,382EPDNEW
RGD ID:7233907
Promoter ID:EPDNEW_H22699
Type:initiation region
Name:VAMP2_1
Description:vesicle associated membrane protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22694  EPDNEW_H22695  EPDNEW_H22697  EPDNEW_H22696  EPDNEW_H22698  EPDNEW_H22702  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38178,162,948 - 8,163,008EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12643 AgrOrtholog
COSMIC VAMP2 COSMIC
Ensembl Genes ENSG00000220205 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000316509 ENTREZGENE
  ENST00000316509.11 UniProtKB/Swiss-Prot
  ENST00000404970.3 UniProtKB/TrEMBL
  ENST00000481878.1 UniProtKB/TrEMBL
  ENST00000488857 ENTREZGENE
  ENST00000488857.5 UniProtKB/TrEMBL
  ENST00000711100.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000220205 GTEx
HGNC ID HGNC:12643 ENTREZGENE
Human Proteome Map VAMP2 Human Proteome Map
InterPro Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synaptobrevin/VAMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V_SNARE_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6844 UniProtKB/Swiss-Prot
NCBI Gene 6844 ENTREZGENE
OMIM 185881 OMIM
PANTHER PTHR45701 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45701:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37267 PharmGKB
PIRSF Synaptobrevin_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS SYNAPTOBREVN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SYNAPTOBREVIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0AA34QW14_HUMAN UniProtKB/TrEMBL
  F8WCA0 ENTREZGENE, UniProtKB/TrEMBL
  J3QRU4 ENTREZGENE, UniProtKB/TrEMBL
  K7ENK9_HUMAN UniProtKB/TrEMBL
  P19065 ENTREZGENE
  P63027 ENTREZGENE
  Q9BUC2 ENTREZGENE
  VAMP2_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary P19065 UniProtKB/Swiss-Prot
  Q9BUC2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-10 VAMP2  vesicle associated membrane protein 2  VAMP2  vesicle-associated membrane protein 2 (synaptobrevin 2)  Symbol and/or name change 5135510 APPROVED