P2RX3 (purinergic receptor P2X 3) - Rat Genome Database
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Gene: P2RX3 (purinergic receptor P2X 3) Homo sapiens
Analyze
Symbol: P2RX3
Name: purinergic receptor P2X 3
RGD ID: 735321
HGNC Page HGNC
Description: Exhibits ATP binding activity; extracellularly ATP-gated cation channel activity; and purinergic nucleotide receptor activity. Involved in cellular response to ATP; inorganic cation transmembrane transport; and protein homotrimerization. Localizes to integral component of plasma membrane and receptor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP receptor; MGC129956; P2X purinoceptor 3; P2X receptor, subunit 3; P2X3; purinergic receptor P2X, ligand gated ion channel, 3; purinergic receptor P2X, ligand-gated ion channel, 3; purinergic receptor P2X3; purinoceptor P2X3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1157,338,352 - 57,372,396 (+)EnsemblGRCh38hg38GRCh38
GRCh381157,335,943 - 57,372,399 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371157,105,826 - 57,139,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,862,525 - 56,894,125 (+)NCBINCBI36hg18NCBI36
Build 341156,862,524 - 56,894,125NCBI
Celera1154,464,979 - 54,477,411 (+)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1153,454,728 - 53,486,434 (+)NCBIHuRef
CHM1_11156,971,953 - 57,003,678 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7566110   PMID:7566120   PMID:8889548   PMID:9016352   PMID:9221902   PMID:11069162   PMID:12270951   PMID:12477932   PMID:12885270   PMID:14520770   PMID:15331767   PMID:15475563  
PMID:17052768   PMID:17895406   PMID:18600577   PMID:18805451   PMID:19456993   PMID:19960242   PMID:20110693   PMID:20308565   PMID:20418063   PMID:20699225   PMID:21098022   PMID:21873635  
PMID:22052556   PMID:22160848   PMID:22378790   PMID:22498660   PMID:22963434   PMID:23382219   PMID:23917247   PMID:23959888   PMID:24223907   PMID:24764033   PMID:24868547   PMID:24989924  
PMID:25336328   PMID:25524252   PMID:25956567   PMID:25979768   PMID:25981553   PMID:25989750   PMID:26184350   PMID:26241848   PMID:26253104   PMID:26517690   PMID:26738991   PMID:26825305  
PMID:26920010   PMID:27129281   PMID:27312548   PMID:27377721   PMID:27379638   PMID:27626375   PMID:28323403   PMID:28639246   PMID:28639248   PMID:28669932   PMID:28728214   PMID:28734869  
PMID:28735873   PMID:28898282   PMID:29674445   PMID:29845934   PMID:31232692  


Genomics

Comparative Map Data
P2RX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1157,338,352 - 57,372,396 (+)EnsemblGRCh38hg38GRCh38
GRCh381157,335,943 - 57,372,399 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371157,105,826 - 57,139,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,862,525 - 56,894,125 (+)NCBINCBI36hg18NCBI36
Build 341156,862,524 - 56,894,125NCBI
Celera1154,464,979 - 54,477,411 (+)NCBI
Cytogenetic Map11q12.1NCBI
HuRef1153,454,728 - 53,486,434 (+)NCBIHuRef
CHM1_11156,971,953 - 57,003,678 (+)NCBICHM1_1
P2rx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,826,893 - 84,867,446 (-)NCBIGRCm39mm39
GRCm39 Ensembl284,828,927 - 84,867,806 (-)Ensembl
GRCm38284,996,549 - 85,037,108 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,998,583 - 85,037,462 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,836,709 - 84,875,991 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,797,391 - 84,836,673 (-)NCBImm8
Celera286,595,241 - 86,634,592 (-)NCBICelera
Cytogenetic Map2DNCBI
P2rx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2370,080,850 - 70,124,664 (-)NCBI
Rnor_6.0 Ensembl372,403,993 - 72,447,801 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0372,403,992 - 72,447,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0378,914,029 - 78,958,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,228,045 - 68,270,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1368,124,416 - 68,167,123 (-)NCBI
Celera369,431,850 - 69,475,670 (-)NCBICelera
Cytogenetic Map3q24NCBI
P2rx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,389,717 - 2,411,008 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,389,717 - 2,410,968 (+)NCBIChiLan1.0ChiLan1.0
P2RX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13160,070,860 - 160,104,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,070,875 - 160,106,120 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01152,579,190 - 52,614,329 (+)NCBIMhudiblu_PPA_v0panPan3
P2RX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,773,930 - 38,801,217 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,772,529 - 38,802,057 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,319,548 - 38,346,782 (-)NCBI
ROS_Cfam_1.01839,455,279 - 39,482,558 (-)NCBI
UMICH_Zoey_3.11839,035,826 - 39,065,122 (-)NCBI
UNSW_CanFamBas_1.01838,609,330 - 38,638,605 (-)NCBI
UU_Cfam_GSD_1.01839,242,142 - 39,269,413 (-)NCBI
P2rx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_02440494715,002,140 - 15,032,591 (-)NCBI
SpeTri2.0NW_0049365815,116,276 - 5,146,378 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,585,926 - 13,617,769 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,584,913 - 13,619,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2213,347,685 - 13,381,122 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P2RX3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,872,124 - 15,906,452 (-)NCBI
P2rx3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248643,233,019 - 3,253,525 (-)NCBI

Position Markers
D11S4401  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371157,137,228 - 57,137,438UniSTSGRCh37
Build 361156,893,804 - 56,894,014RGDNCBI36
Cytogenetic Map11q12UniSTS
HuRef1153,486,112 - 53,486,322UniSTS
D11S2735  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371157,108,832 - 57,108,962UniSTSGRCh37
Build 361156,865,408 - 56,865,538RGDNCBI36
Celera1154,467,862 - 54,467,992RGD
Cytogenetic Map11q12UniSTS
HuRef1153,457,721 - 53,457,851UniSTS
D11S3743  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371157,111,567 - 57,111,668UniSTSGRCh37
Build 361156,868,143 - 56,868,244RGDNCBI36
Celera1154,470,595 - 54,470,696RGD
Cytogenetic Map11q12UniSTS
HuRef1153,460,453 - 53,460,554UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1030
Count of miRNA genes:620
Interacting mature miRNAs:681
Transcripts:ENST00000263314, ENST00000533436, ENST00000534820
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 18 1 211 6 1
Low 131 413 235 139 14 139 145 370 54 39 226 37 13 3
Below cutoff 1760 1110 1256 365 620 283 2316 1276 2580 157 665 1075 87 845 1530 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_002559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011545073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_949950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB016608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP000781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM677534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB462670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY032450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF511148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000263314   ⟹   ENSP00000263314
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1157,338,352 - 57,372,396 (+)Ensembl
RefSeq Acc Id: ENST00000533436
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1157,338,374 - 57,340,727 (+)Ensembl
RefSeq Acc Id: ENST00000534820   ⟹   ENSP00000434166
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1157,347,424 - 57,350,701 (+)Ensembl
RefSeq Acc Id: ENST00000616487   ⟹   ENSP00000484614
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1157,338,475 - 57,370,076 (+)Ensembl
RefSeq Acc Id: NM_002559   ⟹   NP_002550
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,338,352 - 57,372,396 (+)NCBI
GRCh371157,105,841 - 57,137,549 (+)ENTREZGENE
Build 361156,862,525 - 56,894,125 (+)NCBI Archive
HuRef1153,454,728 - 53,486,434 (+)ENTREZGENE
CHM1_11156,971,953 - 57,003,678 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545069   ⟹   XP_011543371
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,336,043 - 57,372,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545070   ⟹   XP_011543372
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,335,943 - 57,372,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545071   ⟹   XP_011543373
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,337,832 - 57,372,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545072   ⟹   XP_011543374
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,337,833 - 57,372,399 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011545073   ⟹   XP_011543375
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,346,660 - 57,372,399 (+)NCBI
Sequence:
RefSeq Acc Id: XR_949950
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,337,828 - 57,369,442 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002550   ⟸   NM_002559
- UniProtKB: P56373 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011543372   ⟸   XM_011545070
- Peptide Label: isoform X1
- UniProtKB: P56373 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011543371   ⟸   XM_011545069
- Peptide Label: isoform X1
- UniProtKB: P56373 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011543373   ⟸   XM_011545071
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011543374   ⟸   XM_011545072
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011543375   ⟸   XM_011545073
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSP00000434166   ⟸   ENST00000534820
RefSeq Acc Id: ENSP00000484614   ⟸   ENST00000616487
RefSeq Acc Id: ENSP00000263314   ⟸   ENST00000263314

Promoters
RGD ID:7220313
Promoter ID:EPDNEW_H15902
Type:single initiation site
Name:P2RX3_1
Description:purinergic receptor P2X 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381157,338,353 - 57,338,413EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q12.1(chr11:57047366-57372313)x3 copy number gain See cases [RCV000138413] Chr11:57047366..57372313 [GRCh38]
Chr11:56814841..57139786 [GRCh37]
Chr11:56571417..56896362 [NCBI36]
Chr11:11q12.1
likely benign
GRCh38/hg38 11q11-12.1(chr11:55316535-57539457)x3 copy number gain See cases [RCV000141200] Chr11:55316535..57539457 [GRCh38]
Chr11:55084011..57306930 [GRCh37]
Chr11:54840587..57063506 [NCBI36]
Chr11:11q11-12.1
uncertain significance
GRCh38/hg38 11q11-12.1(chr11:55319519-58998777)x3 copy number gain See cases [RCV000142757] Chr11:55319519..58998777 [GRCh38]
Chr11:55086995..58766250 [GRCh37]
Chr11:54843571..58522826 [NCBI36]
Chr11:11q11-12.1
pathogenic
GRCh38/hg38 11q12.1(chr11:57372226-57936167)x3 copy number gain See cases [RCV000051908] Chr11:57372226..57936167 [GRCh38]
Chr11:57139699..57703639 [GRCh37]
Chr11:56896275..57460215 [NCBI36]
Chr11:11q12.1
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p11.12-q12.1(chr11:49313405-59008426)x3 copy number gain not provided [RCV000683370] Chr11:49313405..59008426 [GRCh37]
Chr11:11p11.12-q12.1
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_002559.5(P2RX3):c.1003-10C>A single nucleotide variant not provided [RCV000967203] Chr11:57369351 [GRCh38]
Chr11:57136824 [GRCh37]
Chr11:11q12.1
benign
Single allele duplication not provided [RCV000844966] Chr11:55033164..57518726 [GRCh37]
Chr11:11q11-12.1
not provided
NM_002559.5(P2RX3):c.9del (p.Asn2_Cys3insTer) deletion not provided [RCV000910671] Chr11:57338559 [GRCh38]
Chr11:57106033 [GRCh37]
Chr11:11q12.1
likely benign
NM_002559.5(P2RX3):c.434G>A (p.Arg145Gln) single nucleotide variant not provided [RCV000890123] Chr11:57348212 [GRCh38]
Chr11:57115686 [GRCh37]
Chr11:11q12.1
benign
Single allele variation Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8534 AgrOrtholog
COSMIC P2RX3 COSMIC
Ensembl Genes ENSG00000109991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000263314 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000434166 UniProtKB/TrEMBL
  ENSP00000484614 UniProtKB/TrEMBL
Ensembl Transcript ENST00000263314 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000534820 UniProtKB/TrEMBL
  ENST00000616487 UniProtKB/TrEMBL
Gene3D-CATH 2.60.490.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000109991 GTEx
HGNC ID HGNC:8534 ENTREZGENE
Human Proteome Map P2RX3 Human Proteome Map
InterPro P2X3_purnocptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P2X_extracellular_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P2X_purnocptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5024 UniProtKB/Swiss-Prot
NCBI Gene 5024 ENTREZGENE
OMIM 600843 OMIM
PANTHER PTHR10125:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA32863 PharmGKB
PIRSF P2X_purinoceptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS P2X3RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P2XRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE P2X_RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs P2X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087X210_HUMAN UniProtKB/TrEMBL
  H0YDR6_HUMAN UniProtKB/TrEMBL
  P2RX3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q6DK37 UniProtKB/Swiss-Prot
  Q9UQB6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 P2RX3  purinergic receptor P2X 3  P2RX3  purinergic receptor P2X, ligand gated ion channel, 3  Symbol and/or name change 5135510 APPROVED
2015-01-20 P2RX3  purinergic receptor P2X, ligand gated ion channel, 3  P2RX3  purinergic receptor P2X, ligand-gated ion channel, 3  Symbol and/or name change 5135510 APPROVED