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Gene: MYO1B (myosin IB) Homo sapiens
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Symbol: MYO1B
Name: myosin IB
Description: Exhibits ATP binding activity; actin filament binding activity; and microfilament motor activity. Involved in actin filament organization and post-Golgi vesicle-mediated transport. Localizes to several cellular components, including the actin filament; endosome; and perinuclear region of cytoplasm. Colocalizes with the trans-Golgi network membrane; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MMI-alpha; MMIa; MYH-1c; MYO1B variant protein; myosin I alpha; myosin-I alpha; myosin-Ib; myr1; unconventional myosin-Ib
Orthologs:
Mus musculus (house mouse) : Myo1b (myosin IB)  MGI  Alliance
Rattus norvegicus (Norway rat) : Myo1b (myosin Ib)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo1b (myosin IB)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO1B (myosin IB)
Canis lupus familiaris (dog) : MYO1B (myosin IB)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo1b (myosin IB)
Sus scrofa (pig) : MYO1B (myosin IB)
Chlorocebus sabaeus (African green monkey) : MYO1B (myosin IB)
Heterocephalus glaber (naked mole-rat) : Myo1b (myosin IB)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2191,245,185 - 191,425,389 (+)Ensembl
GRCh382191,245,400 - 191,425,386 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372192,110,107 - 192,290,115 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,818,375 - 191,998,287 (+)NCBINCBI36hg18NCBI36
Build 342191,935,635 - 192,115,548NCBI
Celera2185,704,728 - 185,884,766 (+)NCBI
Cytogenetic Map2q32.3NCBI
HuRef2183,969,542 - 184,149,826 (+)NCBIHuRef
CHM1_12192,115,938 - 192,295,960 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MYO1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735320
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.