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Gene: Scn11a (sodium channel, voltage-gated, type XI, alpha) Mus musculus
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Symbol: Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Description: Exhibits voltage-gated sodium channel activity. Involved in regulation of sensory perception of pain and sodium ion transport. Localizes to the C-fiber and plasma membrane. Used to study hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 7. Is expressed in several structures, including alimentary system; central nervous system; immune system; liver and biliary system; and reproductive system. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; pirinixic acid; potassium dichromate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: NaN; NaT; NaV1.9; NSS2; sensory neuron sodium channel 2; SNS2; sodium channel protein type 11 subunit alpha; sodium channel protein type XI subunit alpha; sodium channel, voltage-gated, type XI, alpha polypeptide; voltage-gated sodium channel Nav1.9 variant a; voltage-gated sodium channel Nav1.9 variant b; voltage-gated sodium channel Nav1.9 variant c; voltage-gated sodium channel NAV1.9b; voltage-gated sodium channel subunit alpha Nav1.9
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389119,753,763 - 119,825,456 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379119,662,881 - 119,734,574 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,602,461 - 119,672,558 (-)NCBImm8
Celera9120,223,700 - 120,294,696 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Scn11a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735313
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.