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Gene: Scn11a (sodium channel, voltage-gated, type XI, alpha) Mus musculus
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Symbol: Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
RGD ID: 735313
Description: Exhibits voltage-gated sodium channel activity. Involved in regulation of sensory perception of pain and sodium ion transport. Localizes to C-fiber and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; immune system; liver and biliary system; and reproductive system. Used to study hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 3 and hereditary sensory and autonomic neuropathy type 7. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11); INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; pirinixic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: N; NaN; NaT; NaV1.9; NSS2; S; sensory neuron sodium channel 2; SNS2; sodium channel protein type 11 subunit alpha; sodium channel protein type XI subunit alpha; sodium channel, voltage-gated, type XI, alpha polypeptide; voltage-gated sodium channel Nav1.9 variant a; voltage-gated sodium channel Nav1.9 variant b; voltage-gated sodium channel Nav1.9 variant c; voltage-gated sodium channel NAV1.9b; voltage-gated sodium channel subunit alpha Nav1.9
Orthologs:
Homo sapiens (human) : SCN11A (sodium voltage-gated channel alpha subunit 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Scn11a (sodium voltage-gated channel alpha subunit 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn11a (sodium voltage-gated channel alpha subunit 11)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Canis lupus familiaris (dog) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn11a (sodium voltage-gated channel alpha subunit 11)
Sus scrofa (pig) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Chlorocebus sabaeus (African green monkey) : SCN11A (sodium voltage-gated channel alpha subunit 11)
Heterocephalus glaber (naked mole-rat) : Scn11a (sodium voltage-gated channel alpha subunit 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,582,829 - 119,654,522 (-)NCBI
GRCm389119,753,763 - 119,825,456 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,753,759 - 119,825,456 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,662,881 - 119,734,574 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,602,461 - 119,672,558 (-)NCBImm8
Celera9120,223,700 - 120,294,696 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Scn11a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735313
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.