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Gene: UPB1 (beta-ureidopropionase 1) Homo sapiens
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Symbol: UPB1
Name: beta-ureidopropionase 1
Description: Exhibits beta-ureidopropionase activity and protein homodimerization activity. Involved in beta-alanine biosynthetic process via 3-ureidopropionate; protein homotetramerization; and pyrimidine nucleoside catabolic process. Localizes to extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-alanine synthase; beta-ureidopropionase; BUP-1; BUP1; n-carbamoyl-beta-alanine amidohydrolase; ureidopropionase, beta
Orthologs:
Mus musculus (house mouse) : Upb1 (ureidopropionase, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Upb1 (beta-ureidopropionase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Upb1 (beta-ureidopropionase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : UPB1 (beta-ureidopropionase 1)
Canis lupus familiaris (dog) : UPB1 (beta-ureidopropionase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Upb1 (beta-ureidopropionase 1)
Sus scrofa (pig) : UPB1 (beta-ureidopropionase 1)
Chlorocebus sabaeus (African green monkey) : UPB1 (beta-ureidopropionase 1)
Heterocephalus glaber (naked mole-rat) : Upb1 (beta-ureidopropionase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2224,494,107 - 24,528,390 (+)EnsemblGRCh38hg38GRCh38
GRCh382224,495,060 - 24,528,681 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372224,863,344 - 24,922,553 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,221,251 - 23,252,553 (+)NCBINCBI36hg18NCBI36
Build 342223,215,804 - 23,247,106NCBI
Celera228,690,987 - 8,722,274 (+)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,840,918 - 7,872,203 (+)NCBIHuRef
CHM1_12224,849,971 - 24,881,302 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on UPB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734439
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.