Cacng5 (calcium channel, voltage-dependent, gamma subunit 5) - Rat Genome Database
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Gene: Cacng5 (calcium channel, voltage-dependent, gamma subunit 5) Mus musculus
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Symbol: Cacng5
Name: calcium channel, voltage-dependent, gamma subunit 5
RGD ID: 734379
Description: Predicted to have channel regulator activity and voltage-gated calcium channel activity. Predicted to be involved in several processes, including positive regulation of glutamatergic synaptic transmission; protein localization to organelle; and regulation of neurotransmitter receptor activity. Predicted to localize to AMPA glutamate receptor complex; glutamatergic synapse; and postsynaptic membrane. Is expressed in central nervous system; peripheral nervous system ganglion; and retina. Orthologous to human CACNG5 (calcium voltage-gated channel auxiliary subunit gamma 5); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 1,2-dichloroethane; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: neuronal voltage-gated calcium channel gamma-5 subunit; TARP gamma-5; transmembrane AMPAR regulatory protein gamma-5; voltage dependent calcium channel gamma 5 subunit; voltage-dependent calcium channel gamma-5 subunit
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911107,765,431 - 107,805,881 (-)NCBI
GRCm3811107,874,604 - 107,915,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11107,874,605 - 107,915,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711107,735,919 - 107,772,676 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611107,690,695 - 107,727,452 (-)NCBImm8
Celera11119,610,080 - 119,648,160 (-)NCBICelera
Cytogenetic Map11E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11927536   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16702404   PMID:16985003  
PMID:17475805   PMID:18287559   PMID:21267068   PMID:21873635   PMID:24952961  


Genomics

Comparative Map Data
Cacng5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911107,765,431 - 107,805,881 (-)NCBI
GRCm3811107,874,604 - 107,915,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11107,874,605 - 107,915,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711107,735,919 - 107,772,676 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611107,690,695 - 107,727,452 (-)NCBImm8
Celera11119,610,080 - 119,648,160 (-)NCBICelera
Cytogenetic Map11E1NCBI
CACNG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1766,835,117 - 66,885,486 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1766,835,117 - 66,894,751 (+)EnsemblGRCh38hg38GRCh38
GRCh381766,835,117 - 66,894,751 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371764,831,235 - 64,881,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361762,303,913 - 62,311,819 (+)NCBINCBI36hg18NCBI36
Build 341762,303,912 - 62,311,561NCBI
Celera1761,446,119 - 61,454,026 (+)NCBI
Cytogenetic Map17q24.2NCBI
HuRef1760,262,608 - 60,270,613 (+)NCBIHuRef
CHM1_11764,937,383 - 64,945,388 (+)NCBICHM1_1
Cacng5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01096,122,240 - 96,166,606 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1096,123,397 - 96,131,880 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01095,853,195 - 95,894,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41097,300,594 - 97,309,023 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11097,314,963 - 97,323,393 (-)NCBI
Celera1091,494,396 - 91,501,201 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Cacng5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554786,110,146 - 6,155,034 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554786,110,440 - 6,152,677 (+)NCBIChiLan1.0ChiLan1.0
CACNG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11765,979,469 - 66,031,723 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1765,979,469 - 66,031,723 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01760,771,501 - 60,831,190 (+)NCBIMhudiblu_PPA_v0panPan3
CACNG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl913,578,805 - 13,615,233 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1913,575,902 - 13,587,818 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cacng5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365416,168,186 - 6,209,924 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1213,288,544 - 13,328,017 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11213,288,510 - 13,328,811 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21213,660,097 - 13,696,935 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNG5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1654,561,317 - 54,569,097 (-)Ensembl
ChlSab1.11654,561,040 - 54,612,026 (-)NCBI
Cacng5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248701,518,813 - 1,569,395 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1193048547112653728Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196285639108915558Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196919310122082543Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1197006867110713165Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198461783122082543Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198609643122082543Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199363361122082543Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100167277122082543Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100363360120996339Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101131764122082543Mouse
14700693Ppiq12_mprepulse inhibition QTL 12 (mouse)11101613994114581537Mouse
14700694Ppiq13_mprepulse inhibition QTL 13 (mouse)11101613994114581537Mouse
14700695Ppiq14_mprepulse inhibition QTL 14 (mouse)11101613994114581537Mouse
14700696Ppiq15_mprepulse inhibition QTL 15 (mouse)11101613994114581537Mouse
1300957Pbd1_mpeak bone density 1 (mouse)Not determined11102453297112493297Mouse
4141612Cia40_mcollagen induced arthritis 40 (mouse)Not determined11103383166115130618Mouse
4141702Hmtb6_mhemostasis and thrombosis rebleeding time 6 (mouse)Not determined107725518110629004Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1787
Count of miRNA genes:577
Interacting mature miRNAs:663
Transcripts:ENSMUST00000039071, ENSMUST00000106742
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000039071   ⟹   ENSMUSP00000047888
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11107,874,671 - 107,915,055 (-)Ensembl
RefSeq Acc Id: ENSMUST00000106742   ⟹   ENSMUSP00000102353
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11107,874,605 - 107,911,362 (-)Ensembl
RefSeq Acc Id: NM_001199301   ⟹   NP_001186230
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911107,765,431 - 107,805,881 (-)NCBI
GRCm3811107,874,605 - 107,915,055 (-)NCBI
Celera11119,610,080 - 119,651,874 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_080644   ⟹   NP_542375
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911107,765,431 - 107,802,188 (-)NCBI
GRCm3811107,874,605 - 107,911,362 (-)NCBI
MGSCv3711107,735,919 - 107,772,676 (-)RGD
Celera11119,610,080 - 119,651,874 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248720   ⟹   XP_011247022
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911107,765,497 - 107,772,378 (-)NCBI
GRCm3811107,874,604 - 107,881,544 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_542375   ⟸   NM_080644
- UniProtKB: Q8VHW4 (UniProtKB/Swiss-Prot),   Q544Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186230   ⟸   NM_001199301
- UniProtKB: Q8VHW4 (UniProtKB/Swiss-Prot),   Q544Q4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247022   ⟸   XM_011248720
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000102353   ⟸   ENSMUST00000106742
RefSeq Acc Id: ENSMUSP00000047888   ⟸   ENSMUST00000039071

Promoters
RGD ID:8677142
Promoter ID:EPDNEW_M16602
Type:initiation region
Name:Cacng5_1
Description:Mus musculus calcium channel, voltage-dependent, gamma subunit5 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811107,915,012 - 107,915,072EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2157946 AgrOrtholog
Ensembl Genes ENSMUSG00000040373 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000047888 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000102353 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000039071 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000106742 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro PMP22/EMP/MP20/Claudin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_g5su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCC_gsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:140723 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2157946 ENTREZGENE
NCBI Gene 140723 ENTREZGENE
PANTHER PTHR12107:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cacng5 PhenoGen
PRINTS VDCCGAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VDCCGAMMA5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.87663 ENTREZGENE
UniProt CCG5_MOUSE UniProtKB/Swiss-Prot
  Q544Q4 ENTREZGENE, UniProtKB/TrEMBL
  Q8R4I0_MOUSE UniProtKB/TrEMBL
  Q8VHW4 ENTREZGENE